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OSF-1, Human, Recombinant
一鍵復(fù)制產(chǎn)品信息

貨號(hào)：PCK297

價(jià)格：￥980￥￥￥

規(guī)格：

10μg

10μg

數(shù)量： - +

說(shuō)明書(shū)

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產(chǎn)品概述

產(chǎn)品信息

別名	PTN, Heparin Affin Regulatory Protein (HARP), Heparin-Binding Growth Factor-8 (HBGF-8), Osteoblast-Specif_x0002_ic Factor 1 (OSF-1)
物種	Human
表達(dá)宿主	E.coli
序列信息	MGKKEKPEKKVKKSDCGEWQWSVCVPTSGDCGLGTREGTRTGAECKQTMKTQRCKIPCNWKKQFGAECKYQFQAWGECDLNTALKTRTGSLKRALHNAECQKTVTISKPCGKLTKPKPQAESKKKKKEGKKQEKMLD with polyhistidine tag at the C-terminus.
檢索號(hào)	P21246.1
分子量	19.89 kDa
表觀分子量	18 kDa
標(biāo)簽	His-tag?at?the?C-terminus

產(chǎn)品特性

純度	>98% as determined by SDS-PAGE. Ni-NTA chromatography
內(nèi)毒素	<0.01 EU per 1 μg of the protein by the LAL method.
保存	Lyophilized protein should be stored at -5~-20°C for 1 year. Upon reconstitution, store at 2-8°C for up to 1 week. Further dilute in a buffer containing a carrier protein or stabilizer (e.g.0.1%BSA,10%FBS,5%HSA or 5% trehalose solution), protein aliquots should be stored at -5~-20°C or -80°C for 3-6 months.
運(yùn)輸	Ambient temperature or ice pack.
制劑	The protein was lyophilized from a 0.2 μm filtered solution containing 1X PBS, pH 7.4.
復(fù)融	It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 100 μg/mL.Do Not Vortex! Vigorous shaking may impair the biological activity of the protein.

背景介紹

Pleiotrophin (PTN) also known HBBM, HBGF-8, NEGF1, HARP or HB-GAM is a protein that in humans is encoded by the PTN gene. This protein is expressed in the central and peripheral nervous system and also in several non-neural tissues, notably lung, kidney, gut and bone. Pleiotrophin binds anaplastic lymphoma kinase (ALK) which induces MAPK pathway activation, an important step in the anti-apoptotic signaling of PTN and regulation of cell proliferation.