產(chǎn)品中心Cell Resources
聯(lián)系我們CONTACT US
400-999-210024小時服務(wù)熱線
SCF/ c-Kit (C-6His), Rat, Recombinant
貨號：PCK020
價格：￥1200￥2980￥12680￥18680
規(guī)格：
10μg
- 10μg
- 50μg
- 500μg
- 1mg
產(chǎn)品概述
產(chǎn)品信息
| 別名 | Kit Ligand; Hematopoietic Growth Factor KL; Mast cell Growth Factor; MGF; Steel factor; Stem cell factor; SCF |
| 物種 | Rat |
| 表達宿主 | E.coli |
| 序列信息 | Gln26-Ala189 |
| 檢索號 | P21581 |
| 分子量 | 19.3 kDa |
| 表觀分子量 | 18 kDa |
| 標簽 | C-6His |
產(chǎn)品特性
| 純度 | >95% as determined by reducing SDS-PAGE. |
| 內(nèi)毒素 | <1.0 EU per μg as determined by LAL test. |
| 保存 | Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months. |
| 運輸 | Ambient temperature or ice pack. |
| 制劑 | Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
| 復(fù)融 | Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled waterPlease aliquot the reconstituted solution to minimize freeze-thaw cycles. |
背景介紹
Stem cell factor (SCF), is the Ligand for the Receptor-type Protein-tyrosine kinase KIT. It plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/ SCF binding can activate several signaling pathways. It also promotes phosphorylation of PIK3R1, which is the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1. KITLG/ SCF and KIT also transmit signals via GRB2 and activation of RAS, RAF1 and the MAP kinases MAPK1/ ERK2 and/ or MAPK3/ ERK1. KITLG/ SCF and KIT promote activation of STAT family members STAT1, STAT3 and STAT5.
FAQs
Q：{{item.question}}
A：
暫無數(shù)據(jù)
產(chǎn)品資料
注：百度瀏覽器無法支持掃一掃功能，請輸入識別碼，獲取相應(yīng)產(chǎn)品資料
識別碼示意圖
