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Flt-3L/ Flt3LG (C-6His), Human, Recombinant
貨號：PCK090
價格：￥1380￥3680￥17480￥25680
規(guī)格：
10μg
- 10μg
- 50μg
- 500μg
- 1mg
產(chǎn)品概述
產(chǎn)品信息
| 別名 | Fms-related Tyrosine Kinase 3 Ligand; Flt3 Ligand; Flt3L; SL Cytokine; FLT3LG |
| 物種 | Human |
| 表達宿主 | Human Cells |
| 序列信息 | Thr27-Pro184 |
| 檢索號 | P49771 |
| 分子量 | 19 kDa |
| 表觀分子量 | 24-32 kDa |
| 標簽 | C-6His |
| 生物活性 | Immobilized Human FLT3LG (C-6His) 5 μg/ml (100 μl/well) can bind Human FLT3 (C-Fc). The EC50 of Human FLT3 (C-Fc) is not higher than 10 ng/ml. |
產(chǎn)品特性
| 純度 | >95% as determined by reducing SDS-PAGE. |
| 內(nèi)毒素 | <1.0 EU per μg as determined by LAL test. |
| 保存 | Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months. |
| 運輸 | Ambient temperature or ice pack. |
| 制劑 | Lyophilized from a 0.2 μm filtered solution of 20mM Tris, 150mM NaCl, pH 8.0. |
| 復融 | Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
背景介紹
Fms-Related Tyrosine Kinase 3 Ligand (FLT3LG) is a hematopoietic four helical bundle Cytokine. Mature human Flt-3 Ligand consists of a extracellular domain (ECD) with a Cytokine-like domain and a juxtamembrane tether region, a transmembrane segment, and a cytoplasmic tail. Human and mouse Flt-3 Ligand show cross-species activity. Flt-3 Ligand is expressed as a noncovalently-linked dimer by T cells and bone marrow and thymic fibroblasts.It is structurally homologous to stem cell factor (SCF) and colony stimulating facor 1 (CSF-1). In synergy with other Growth Factors, Flt3 Ligand stimulates the proliferation and differentiation of various blood cell progenitors by activiation of Flt 3 Receptor.
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