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BCMA/ TNFRSF17 (C-Fc), Human, Recombinant
一鍵復(fù)制產(chǎn)品信息

貨號(hào)：PCK108

價(jià)格：￥980￥2580￥12480￥18680

規(guī)格：

10μg

10μg
50μg
500μg
1mg

數(shù)量： - +

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產(chǎn)品概述

產(chǎn)品信息

別名	Tumor necrosis factor Receptor superfamily member 17; TNFRSF17; B-cell maturation Protein; CD269
物種	Human
表達(dá)宿主	Human Cells
序列信息	Met1-Ala54
檢索號(hào)	Q02223
分子量	32.8kDa
表觀分子量	38-40kDa
生物活性	Loaded Mouse BAFF-mFc on AMC Biosensor, can bind Human BCMA-Fc with an affinity constant of 0.44 nM as determined in BLI assay.

產(chǎn)品特性

純度	>95% as determined by reducing SDS-PAGE.
內(nèi)毒素	<1.0 EU per μg as determined by LAL test.
保存	Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months.
運(yùn)輸	Ambient temperature or ice pack.
制劑	Lyophilized from a 0.2 μm filtered solution of PBS,pH 7.4.
復(fù)融	Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

背景介紹

B cell maturation Protein (BCMA) is a type III membrane Protein which belongs to the TNF Receptor superfamily (TNFRSF17). BCMA contains one extracellular cysteine rich domain, as well as TACI. Human BCMA is a 184 amino acid (aa) Protein consisting of a 54 aa extracellular domain, a 23 aa transmembrane domain, and a 107 aa intracellular domain. Mouse and human BCMA share 62% amino acid identity. BCMA is mainly expressed in immune organs and mature B cell lines. BCMA appears to be localized to the Golgi compartment. BCMA may play an important role in B cell development, function and regulation.