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IL-12B/ IL-12 p40, Human, Recombinant
一鍵復(fù)制產(chǎn)品信息

貨號(hào)：PCK172

價(jià)格：￥1380￥3680￥17480￥25680

規(guī)格：

10μg

10μg
50μg
500μg
1mg

數(shù)量： - +

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產(chǎn)品概述

產(chǎn)品信息

別名	Interleukin-12 subunit beta; IL-12B; Cytotoxic lymphocyte maturation factor 40 kDa subunit; CLMF p40; IL-12 subunit p40; NK cell stimulatory factor chain 2; NKSF2; IL12B; NKSF2
物種	Human
表達(dá)宿主	Human Cells
序列信息	?Ile23-Ser328
檢索號(hào)	P29460
分子量	34.6 kDa
表觀分子量	40-47 kDa

產(chǎn)品特性

純度	>95% as determined by reducing SDS-PAGE.
內(nèi)毒素	<1.0 EU per μg as determined by LAL test.
保存	Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months.
運(yùn)輸	Ambient temperature or ice pack.
制劑	Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
復(fù)融	Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

背景介紹

Interleukin-12 subunit beta (IL-12B) belongs to the type I Cytokine Receptor family. It contains 1 fibronectin type-III domain and 1 Ig-like C2-type domain. IL-12B is a Cytokine that acts on T and natural killer cells, and has a broad array of biological activities. IL-12 is a disulfide-linked heterodimer composed of the 40 kD Cytokine Receptor encoded by IL12B and a 35 kD subunit encoded by IL12A. IL12 is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. It has been found to be important for sustaining a sufficient number of memory/ effector Th1 cells to mediate long-term protection to an intracellular pathogen.