當(dāng)前位置：首頁(yè) >> 產(chǎn)品中心 >> 輔助試劑 >> 細(xì)胞因子 >> Human

產(chǎn)品中心Cell Resources

聯(lián)系我們CONTACT US

400-999-210024小時(shí)服務(wù)熱線
[email protected]銷(xiāo)售郵箱

Wnt-3a, Human, Recombinant（待上架）
一鍵復(fù)制產(chǎn)品信息

貨號(hào)：PCK370

價(jià)格：￥108031802468036680

規(guī)格：

10μg

10μg
50μg
500μg
1mg

數(shù)量： - +

說(shuō)明書(shū)

在線咨詢

產(chǎn)品概述

產(chǎn)品信息

別名	MGC119418; MGC119419; MGC119420
物種	Human
表達(dá)宿主	HEK-293
序列信息	MAPLGYFLLLCSLKQALGSYPIWWSLAVGPQYSSLGSQPILCASIPGLVPKQLRFCRNYVEIMPSVAEGIKIGIQECQHQFRGRRWNCTTVHDSLAIFGPVLDKATRESAFVHAIASAGVAFAVTRSCAEGTAAICGCSSRHQGSPGKGWKWGGCSEDIEFGGMVSREFADARENRPDARSAMNRHNNEAGRQAIASHMHLKCKCHGLSGSCEVKTCWWSQPDFRAIGDFLKDKYDSASEMVVEKHRESR
檢索號(hào)	P56704
分子量	105.7 kDa
生物活性	Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (PubMed:20093360, PubMed:21244856, PubMed:24841207, PubMed:26902720). Required for normal embryonic mesoderm development and formation of caudal somites. Required for normal morphogenesis of the developing neural tube (By similarity). Mediates self-renewal of the stem cells at the bottom on intestinal crypts (in vitro) (PubMed:26902720).

產(chǎn)品特性

純度	>95% as determined by SDS-PAGE. Ni-NTA chromatography.
內(nèi)毒素	<0.1 EU per 1 μg of the protein by the LAL method.
保存	Lyophilized protein should be stored at -5~-20°C for 1 year. Upon reconstitution,store at 2-8°C for up to 1 week. Further dilute in a buffer containing a carrier protein or stabilizer (e.g.0.1% BSA, 10% FBS, 5% HSA or 5% trehalose solution), protein aliquots should be stored at -5~-20°C or -80°C for 3-6 months.
運(yùn)輸	Ambient temperature or ice pack.
制劑	The protein was lyophilized from a 0.2 μm filtered solution containing 1×PBS, pH8.0.
復(fù)融	It is recommended to reconstitute the lyophilized protein in sterile water to aconcentration not less than 100 μg/mL. Do Not Vortex! Vigorous shaking may impair the biological activity of the protein.

背景介紹

Wnt-3a is one of 19 vertebrate members of the Wingless-type MMTV integration site (Wnt) family of highly conserved cysteine-rich secreted glycoproteins important for normal developmental processes.Required for normal embryonic mesoderm development and formation of caudal somites. Required for normal morphogenesis of the developing neural tube (By similarity). Mediates self-renewal of the stem cells at the bottom on intestinal crypts (in vitro).