產品中心Cell Resources
聯(lián)系我們CONTACT US
400-999-210024小時服務熱線
產品概述
產品信息
| 別名 | PDGFBB; PDGF-BB |
| 物種 | Human |
| 表達宿主 | E.coli |
| 序列信息 | Ser82-Thr190 |
| 檢索號 | P01127 |
| 分子量 | 12.42 kDa |
| 表觀分子量 | 14 kDa |
| 生物活性 | Measured in a cell proliferation assay using BALB/c 3T3 cells. The ED50 for this effect is 5-20 ng/ml. |
產品特性
| 純度 | >95% as determined by reducing SDS-PAGE. |
| 內毒素 | <1.0 EU per μg as determined by LAL test. |
| 保存 | Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months. |
| 運輸 | Ambient temperature or ice pack. |
| 制劑 | Lyophilized from a 0.2 μm filtered solution of 20mM NaAc-HAc, pH 4.5. |
| 復融 | Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
背景介紹
Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/ VEGF Growth Factor family. Platelet-Derived Growth Factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-Derived Growth Factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma.Binding of PDGFB to its Receptor elicits a variety of cellular responses. In addition, PDGFB is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound.
FAQs
Q：{{item.question}}
A：
暫無數(shù)據(jù)
產品資料
注：百度瀏覽器無法支持掃一掃功能，請輸入識別碼，獲取相應產品資料
識別碼示意圖
