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TGFβ2/ TGFB2, Human, Recombinant
貨號(hào)：PCK092
價(jià)格：￥1780￥4980￥17480￥27980
規(guī)格：
10μg
- 10μg
- 50μg
- 500μg
- 1mg
產(chǎn)品概述
產(chǎn)品信息
| 別名 | Transforming Growth Factor beta-2; TGFB2; Polyergin; G-TSF; Glioblastoma-Derived T-cell suppressor factor; Cetermin; BSC-1 cell growth inhibitor; TGF-beta-2 |
| 物種 | Human |
| 表達(dá)宿主 | Human Cells |
| 序列信息 | Ala303-Ser414 |
| 檢索號(hào) | P61812 |
| 分子量 | 12.7 kDa |
| 表觀分子量 | 12 kDa |
| 生物活性 | Measured by its ability to inhibit the IL-4-dependent proliferation of TF-1 cells.The ED50 for this effect is 30-180pg/ml. |
產(chǎn)品特性
| 純度 | >95% as determined by reducing SDS-PAGE. |
| 內(nèi)毒素 | <1.0 EU per μg as determined by LAL test. |
| 保存 | Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months. |
| 運(yùn)輸 | Ambient temperature or ice pack. |
| 制劑 | Lyophilized from a 0.2 μm filtered solution of 4 mM HCl. |
| 復(fù)融 | Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
背景介紹
Transforming Growth Factor beta-2 (TGF-β2) is a secreted protein which belongs to the TGF-beta family. It is known as a cytokine that performs many cellular functions and has a vital role during embryonic development. The precursor is cleaved into mature TGF-beta-2 and LAP, which remains non-covalently linked to mature TGF-beta-2 rendering it inactive. It is an extracellular glycosylated Protein. It is known to suppress the effects of Interleukin dependent T-cell tumors. Defects in TGFB2 may be a cause of non-syndromic aortic disease (NSAD).
參考文獻(xiàn)
文獻(xiàn)列表
-
TGF-β2-induced NEAT1 regulates lens epithelial cell proliferation, migration and EMT by the miR-26a-5p/FANCE axis(2021/11/18)
作者：Xiaohui Yu, Shaoyi Liu, Chengfang Li
期刊：International Journal of Ophthalmology
影響因子 ：1.400
引用產(chǎn)品：PCK092
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