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產(chǎn)品概述
名稱 | CoC1/DDP (人卵巢癌細(xì)胞CoC1順鉑耐藥亞株) (STR鑒定正確) |
別稱 | COC1/DDP |
種屬 | 人 |
生長特性 | 懸浮細(xì)胞 |
細(xì)胞形態(tài) | 淋巴母細(xì)胞樣 |
凍存條件 | 凍存液:55% 基礎(chǔ)培養(yǎng)基+40% FBS+5% DMSO 溫度:液氮 |
培養(yǎng)方案A(默認(rèn)) |
培養(yǎng)條件:
氣相:空氣,95%;CO2,5%, 溫度:37℃
|
推薦傳代比例 | 1:2-1:4 |
推薦換液頻率 | 2-3次/周 |
背景描述 | COC1/DDP細(xì)胞是由陳惠楨教授等用藥物劑量增選法篩選獲得的COC1細(xì)胞耐藥亞株。COC1/DDP細(xì)胞對順鉑(DDP 1μg/mL)的耐受性是親本株(COC1細(xì)胞)的6.5倍;同時(shí),對卡鉑(CBD-CA)、絲裂霉素C(MMC)也具有不同程度的交叉耐受性。COC1/DDP細(xì)胞可用于卵巢腫瘤治療的體外試驗(yàn)研究。 |
年齡(性別) | 女性 |
組織來源 | 卵巢 |
細(xì)胞類型 | 腫瘤細(xì)胞 |
腫瘤類型 | 卵巢癌細(xì)胞 |
生物安全等級 | BSL-1 |
致瘤性 | Yes, forms tumors in nude mice. |
保藏機(jī)構(gòu) | CCTCC;GDC0058 |
STR鑒定
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STR位點(diǎn)信息
Amelogenin X CSF1PO 11 D2S1338 24 D3S1358 15 D5S818 12,13 D7S820 9,13,14 D8S1179 12,13 D13S317 11,12 D16S539 10,12,13 D18S51 12,18 D19S433 14,15 D21S11 30,32.2 FGA 23,24 PentaD 11 PentaE 5,14 TH01 6,7 TPOX 8 vWA 16,17,20 D6S1043 11,13 D12S391 18,22 D2S441 11,13,14 -
STR鑒定圖
參考文獻(xiàn)
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Oncogenic microRNA-181d binding to OGT contributes to resistance of ovarian cancer cells to cisplatin (2012-01-20)
作者:Wei Huang:1.Department of Gynaecology, Hunan Provincial People's Hospital, (The First Affiliated Hospital of Hunan Normal University), Changsha, 410000, P. R. China. ; Ling Chen:1.Department of Gynaecology, Hunan Provincial People's Hospital, (The First Affiliated Hospital of Hunan Normal University), Changsha, 410000, P. R. China. ; Kean Zhu:1.Department of Gynaecology, Hunan Provincial People's Hospital, (The First Affiliated Hospital of Hunan Normal University), Changsha, 410000, P. R. China. ; Donglian Wang:1.Department of Gynaecology, Hunan Provincial Maternal and Child Health Care Hospital, Changsha, 410008, P. R. China. [email protected]. ;
期刊:Oncogenic microRNA-181d binding to OGT contributes to resistance of ovarian cancer cells to cisplatin
DOI:10.1038/s41420-021-00715-6
影響因子 :7.0
引用產(chǎn)品: CoC1 細(xì)胞 , CoC1/DDP 細(xì)胞 , SK-OV-3 細(xì)胞
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