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AML12 (小鼠正常肝細(xì)胞) (STR鑒定正確)
貨號(hào)：CL-0602
規(guī)格：1×10?cells/T25培養(yǎng)瓶
價(jià)格： ￥1600
生長(zhǎng)培養(yǎng)基：DMEM/F12＋10% FBS＋0.5% ITS-G（100×）＋40ng/ml Dexamethasone＋1% P/S
產(chǎn)品概述
| 名稱 | AML12 (小鼠正常肝細(xì)胞) (STR鑒定正確) |
| 別稱 | AML-12; AML 12; Alpha Mouse Liver 12 |
| 種屬 | 小鼠 |
| 生長(zhǎng)特性 | 貼壁細(xì)胞 |
| 細(xì)胞形態(tài) | 上皮細(xì)胞樣 |
| 凍存條件 | 凍存液：55% 基礎(chǔ)培養(yǎng)基+40%FBS+5%DMSO 溫度：液氮 |
| 培養(yǎng)方案A（默認(rèn)） |
生長(zhǎng)培養(yǎng)基:
培養(yǎng)條件:
氣相：空氣，95%；CO2，5%, 溫度：37℃
|
| 推薦傳代比例 | 1:4-1:6 |
| 推薦換液頻率 | 2-3次/周 |
| 背景描述 | The AML12 (alpha mouse liver 12) cell line was established from hepatocytes from a mouse (CD1 strain, line MT42) transgenic for human TGF alpha. |
| 年齡（性別） | 雄性；3月齡 |
| 組織來(lái)源 | 肝臟 |
| 細(xì)胞類型 | 自發(fā)永生化細(xì)胞 |
| 生物安全等級(jí) | BSL-1 |
| 倍增時(shí)間 | ~37 hours |
| 致瘤性 | NO |
| 基因表達(dá)情況 | albumin; human transforming growth factor alpha (TGF alpha); mouse TGF alpha. |
| 保藏機(jī)構(gòu) | ATCC; CRL-2254 BCRC; 60326 BCRJ; 0354 |
STR鑒定
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STR位點(diǎn)信息
18-3 21 6-7 12 5-5 14,15 X-1 26 1-2 13 7-1 29 8-1 14,15 1-1 11 19-2 13 15-3 21.3 12-1 19 6-4 16 4-2 20.3 3-2 12 2-1 9 13-1 15.1,15.2
11-2 18,19 17-2 14,15 -
STR鑒定圖
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參考文獻(xiàn)
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DOI：10.1038/s41467-023-40327-5
影響因子 ：16.600
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Dietary Selenium Alleviated Mouse Liver Oxidative Stress and NAFLD Induced by Obesity by Regulating the KEAP1/NRF2 Pathway(2022/02/10)
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Qizhu Anticancer Prescription enhances immunosurveillance of liver cancer cells by regulating p21-dependent secretory phenotypes(2024/05/31)
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影響因子 ：5.400
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Identification and validation of cuproptosis-related molecular clusters in non-alcoholic fatty liver disease(2024/01/03)
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METTL3 Modulates TXNIP Expression to Affect the Activation of NLRP3 Inflammasome in Hepatic Cells Under Oxygen–Glucose Deprivation/Reperfusion Injury(2024/01/18)
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影響因子 ：4.900
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6-Gingerol attenuates hepatic ischemia/reperfusion injury through regulating MKP5-mediated P38/JNK pathway(2024/04/02)
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作者：Huiying Shang, Xian Liu, Jinchao Pan
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DOI：10.1038/s41598-023-50454-0
影響因子 ：4.600
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Heme oxygenase 1 alleviates nonalcoholic steatohepatitis by suppressing hepatic ferroptosis(2023/07/08)
作者：Xiwei Yuan, Lu Li, Ying Zhang
期刊：Lipids in Health and Disease
DOI：10.1186/s12944-023-01855-7
影響因子 ：4.500
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Catalpol inhibits hepatic stellate cell activation by reducing the formation and changing the contents of hepatocyte-derived extracellular vesicles(2022/12/12)
作者：Zhengyuan Xie, Hengwei Cao, Qing Wang
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DOI：10.1007/s12079-022-00716-9
影響因子 ：4.100
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BNIP3 in hypoxia-induced mitophagy: novel insights and promising target for non-alcoholic fatty liver disease(2024/01/11)
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期刊：INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
DOI：10.1016/j.biocel.2024.106517
影響因子 ：4.000
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Oral administration of kynurenic acid delays the onset of type 2 diabetes in Goto-Kakizaki rats(2023/06/27)
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DOI：10.1016/j.heliyon.2023.e17733
影響因子 ：4.000
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Octreotide ameliorates hepatic ischemia-reperfusion injury through SNHG12/TAF15-mediated Sirt1 stabilization and YAP1 transcription(2022/03/18)
作者：Shuangfa Zou, Yanhua Peng, Chumei Zheng
期刊：Toxicology And Applied Pharmacology
DOI：10.1016/j.taap.2022.115975
影響因子 ：3.800
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Suppression of SIRT1/FXR signaling pathway contributes to oleanolic acid-induced liver injury(2023/04/05)
作者：Songjie Liao, Xiaolong Fu, Jianxiang Huang
期刊：TOXICOLOGY AND APPLIED PHARMACOLOGY
DOI：10.1016/j.taap.2023.116509
影響因子 ：3.800
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SIRT5 alleviates hepatic ischemia and reperfusion injury by diminishing oxidative stress and inflammation via elevating SOD1 and IDH2 expression(2022/08/19)
作者：Daofeng Zheng, Qiwen zeng, Diao He
期刊：EXPERIMENTAL CELL RESEARCH
DOI：10.1016/j.yexcr.2022.113319
影響因子 ：3.700
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Sevoflurane blocks KLF5-mediated transcriptional activation of ITGB2 to inhibit macrophage infiltration in hepatic ischemia/reperfusion injury(2024/05/14)
作者：Ye Li, Weinian Gao, Shuyan Lei
期刊：JOURNAL OF GENE MEDICINE
DOI：10.1002/jgm.3692
影響因子 ：3.500
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Low?dose ionizing radiation attenuates high glucose?induced hepatic apoptosis and immune factor release via modulation of a miR?155?SOCS1 axis(2023/07/24)
作者：Hongqiong Fan, Shanshan Liu, Benzheng Jiao
期刊：Molecular Medicine Reports
影響因子 ：3.400
-
Running title: AMPK contributes to liver injury(2023/02/27)
作者：Jianxiang Huang, Songjie Liao, Xiaolong Fu
期刊：JOURNAL OF APPLIED TOXICOLOGY
DOI：10.1002/jat.4456
影響因子 ：3.300
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Inhibition of ROS/caspase-3/GSDME-mediated pyroptosis alleviates high glucose-induced injury in AML-12 cells(2024/05/08)
作者：Xinrui Wang, Shengying Ye, Linge Tong
期刊：TOXICOLOGY IN VITRO
影響因子 ：3.200
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Circadian rhythm disorders elevate macrophages cytokines release and promote multiple tissues/organs dysfunction in mice(2022/03/02)
作者：Zhen Sun, Lihua Li, Zhixin Yan
期刊：Physiol Behav
DOI：10.1016/j.physbeh.2022.113772
影響因子 ：2.900
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The augment effects of magnesium hydride on the lipid lowering effect of atorvastatin: an in vivo and in vitro investigation(2024/03/28)
作者：Wanqiu Chen, Yinyin Zhang, Gen Miao
期刊：Medical Gas Research
DOI：10.4103/mgr.MEDGASRES-D-23-00047
影響因子 ：2.900
引用產(chǎn)品：CL-0602
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Basic fibroblast growth factor protects against liver ischemia-reperfusion injury via the Nrf2/Hippo signaling pathway(2022/09/08)
作者：Xixi Chen, Gaozan Tong, Saizhen Chen
期刊：TISSUE & CELL
DOI：10.1016/j.tice.2022.101921
影響因子 ：2.600
引用產(chǎn)品：CL-0602
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Ganoderic acid A attenuated hepatic impairment by down-regulating the intracellular JAK2-STAT3 signaling pathway in induced mushroom poisoning(2024/01/15)
作者：Chenggen Xiao, Guoqing Huang, Xiaoxia Cao
期刊：American Journal of Translational Research
DOI：PMID:38322557
影響因子 ：2.200
引用產(chǎn)品：CL-0602
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HMG-CoA reductase inhibitor from the endophytic fungus Colletotrichum Capsici(2023/11/28)
作者：Yuanyuan Lu, Qianqian Xu, Liangfang Pang
期刊：NATURAL PRODUCT RESEARCH
DOI：10.1080/14786419.2023.2289085
影響因子 ：2.200
引用產(chǎn)品：CL-0602
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In vitro and in vivo metabolic profiling of PD105, a PI3Kδ inhibitor, using UHPLC-Q-Exactive Plus-MS(2023/03/06)
作者：Panhong Wei, Minghai Tang, Ziyan Ma
期刊：XENOBIOTICA
DOI：10.1080/00498254.2023.2188070
影響因子 ：1.800
引用產(chǎn)品：CL-0602
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