產(chǎn)品中心Cell Resources
聯(lián)系我們CONTACT US
400-999-210024小時(shí)服務(wù)熱線
SK-Hep-1 (人肝竇內(nèi)皮細(xì)胞) (STR鑒定正確)
貨號(hào)：CL-0212
規(guī)格：1×10?cells/T25培養(yǎng)瓶
價(jià)格： ￥2000
生長培養(yǎng)基：MEM（含NEAA）＋10% FBS＋1% P/S
產(chǎn)品概述
| 名稱 | SK-Hep-1 (人肝竇內(nèi)皮細(xì)胞) (STR鑒定正確) |
| 別稱 | SK-Hep-1; SK HEP-1; SK HEP 01; SK-Hep1; Sk-Hep1; SK Hep1; SKHEP-1; SKHEP1; SKHep1; SK_HEP1 |
| 種屬 | 人 |
| 生長特性 | 貼壁細(xì)胞 |
| 細(xì)胞形態(tài) | 上皮細(xì)胞樣 |
| 凍存條件 | 凍存液：55% 基礎(chǔ)培養(yǎng)基+40%FBS+5%DMSO 溫度：液氮 |
| 培養(yǎng)方案A（默認(rèn)） |
生長培養(yǎng)基:
培養(yǎng)條件:
氣相：空氣，95%；CO2，5%, 溫度：37℃
|
| 推薦傳代比例 | 1:2-1:4 |
| 推薦換液頻率 | 2-3次/周 |
| 背景描述 | SK-HEP-1細(xì)胞已被鑒定為內(nèi)皮來源，最新研究表明該細(xì)胞系為肝竇內(nèi)皮細(xì)胞。SK-HEP-1細(xì)胞來源于52歲男性，染色體在亞三倍體范圍內(nèi)。在裸鼠中，SK-HEP-1細(xì)胞能形成與肝癌相一致的大細(xì)胞癌。 |
| 年齡（性別） | 男性；52歲 |
| 組織來源 | 肝，腹水 |
| 細(xì)胞類型 | 自發(fā)永生化細(xì)胞系 |
| 生物安全等級(jí) | BSL-1 |
| 倍增時(shí)間 | ~30 hours |
| 致瘤性 | Yes, in nude mice; forms large cell carcinoma consistent with hepatoma. |
| 保藏機(jī)構(gòu) | ATCC; HTB-52 DSMZ; ACC-141 ECACC; 91091816 |
STR鑒定
-
STR位點(diǎn)信息
Amelogenin X CSF1PO 11,12 D2S1338 20,23 D3S1358 16 D5S818 10,13 D7S820 8,11 D8S1179 13,14 D13S317 8,12 D16S539 12 D18S51 13,15 D19S433 12,15.2 D21S11 29,31 FGA 17 PentaD 13,14 PentaE 21 TH01 7,9 TPOX 9 vWA 14,17 D6S1043 11 D12S391 18,19 D2S441 12.3,14 -
STR鑒定圖
-
參考文獻(xiàn)
-
SGOL2 is a novel prognostic marker and fosters disease progression via a MAD2-mediated pathway in hepatocellular carcinoma(2022/11/15)
作者：Hu, Qingqing, Liu, Qiuhong, Zhao, Yalei, Zhang, Lingjian, Li, Lanjuan
期刊：Biomarker Research
DOI：10.1186/s40364-022-00422-z
影響因子 ：11.100
-
Neuropilin-1 aggravates liver cirrhosis by promoting angiogenesis via VEGFR2-dependent PI3K/Akt pathway in hepatic sinusoidal endothelial cells(2019/05/03)
作者：Le Wang, Yuemin Feng, Xiaoyu Xie
期刊：EBioMedicine
DOI：10.1016/j.ebiom.2019.04.050
影響因子 ：11.100
引用產(chǎn)品：CL-0212
-
Nanoparticle-Stabilized Emulsion Bioink for Digital Light Processing Based 3D Bioprinting of Porous Tissue Constructs(2022/03/04)
作者：Jie Tao, Shunyao Zhu, Nazi Zhou
期刊：Advanced Healthcare Materials
影響因子 ：11.092
-
ncRNAs-mediated high expression of TICRR promotes tumor cell proliferation and migration and is correlated with poor prognosis and tumor immune infiltration of hepatocellular carcinoma(2022/09/19)
作者：Kejie He, Yangfan Zhang, Laiying Liang
期刊：Molecular Therapy-Nucleic Acids
DOI：10.1016/j.omtn.2022.09.007
影響因子 ：8.800
-
Comprehensive analysis of ubiquitin‐specific protease 1 reveals its importance in hepatocellular carcinoma(2020/09/19)
作者：Yalei Zhao, Chen Xue, Zhongyang Xie
期刊：Cell Proliferation
影響因子 ：8.500
引用產(chǎn)品：CL-0212
-
LAGE3 promoted cell proliferation, migration, and invasion and inhibited cell apoptosis of hepatocellular carcinoma by facilitating the JNK and ERK signaling pathway(2021/11/27)
作者：Ying Xing,Yang Liu，Zhong Qi
期刊：Cellular & Molecular Biology Letters
DOI：10.1186/s11658-021-00295-4
影響因子 ：8.300
-
5′-tiRNA-Gln inhibits hepatocellular carcinoma progression by repressing translation through the interaction with eukaryotic initiation factor 4A-I(2023/03/28)
作者：Chengdong Wu, Dekai Liu, Lufei Zhang
期刊：Frontiers of Medicine
影響因子 ：8.100
-
BCLAF1 binds SPOP to stabilize PD-L1 and promotes the development and immune escape of hepatocellular carcinoma(2024/02/10)
作者：Zongdong Yu, Xiang Wu, Jie Zhu
期刊：CELLULAR AND MOLECULAR LIFE SCIENCES
DOI：10.1007/s00018-024-05144-z
影響因子 ：8.000
引用產(chǎn)品：CL-0212
-
Identification and analysis of C17orf53 as a prognostic signature for hepatocellular carcinoma(2022/11/28)
作者：Yalei Zhao, Lingjian Zhang, Qingqing Hu, Danhua Zhu, Zhongyang Xie
期刊：COMPUTERS IN BIOLOGY AND MEDICINE
DOI：10.1016/j.compbiomed.2022.106348
影響因子 ：7.700
引用產(chǎn)品：CL-0212
-
Constructing a disulfidptosis-related prognostic signature of hepatocellular carcinoma based on single-cell sequencing and weighted co-expression network analysis(2024/05/17)
作者：Zelin Tian, Junbo Song, Jiang She
期刊：APOPTOSIS
DOI：10.1007/s10495-024-01968-z
影響因子 ：7.200
引用產(chǎn)品：CL-0212
-
Dual role of PID1 in regulating apoptosis induced by distinct anticancer-agents through AKT/Raf-1-dependent pathway in hepatocellular carcinoma(2023/04/28)
作者：Jian Yang, Senlin Li, Jialuo He
期刊：Cell Death Discovery
DOI：10.1038/s41420-023-01405-1
影響因子 ：7.000
-
Transfer RNA‐derived fragment 5′tRF‐Gly promotes the development of hepatocellular carcinoma by direct targeting of carcinoembryonic antigen‐related cell adhesion molecule 1(2022/08/16)
作者：Dekai Liu, Chengdong Wu, Jingjie Wang
期刊：CANCER SCIENCE
影響因子 ：6.518
引用產(chǎn)品：CL-0212
-
VEZF1, destabilized by STUB1, affects cellular growth and metastasis of hepatocellular carcinoma by transcriptionally regulating PAQR4(2022/10/14)
作者：Xiaobao Shi, Pengfei Zhao, Gang Zhao
期刊：Cancer Gene Therapy
DOI：10.1038/s41417-022-00540-8
影響因子 ：6.400
-
A triggered DNA nanomachine with enzyme-free for the rapid detection of telomerase activity in a one-step method(2024/02/27)
作者：Huajie Pang, Yanan Peng, Rui Zhang
期刊：ANALYTICA CHIMICA ACTA
影響因子 ：6.200
引用產(chǎn)品：CL-0212
-
Bufalin enhances the killing efficacy of NK cells against hepatocellular carcinoma by inhibiting MICA shedding(2021/10/19)
作者：Rao Fu, Fangjing Yu, Weiqi Wu
期刊：International Immunopharmacology
DOI：10.1016/j.intimp.2021.108195
影響因子 ：5.714
-
TRIM21 is critical in regulating hepatocellular carcinoma growth and response to therapy by altering the MST1/YAP pathway(2024/03/12)
作者：Bo Shu, Yingxia Zhou, Guoqiong Lei
期刊：CANCER SCIENCE
影響因子 ：5.700
引用產(chǎn)品：CL-0212
-
Celecoxib reduces hepatic vascular resistance in portal hypertension by amelioration of endothelial oxidative stress(2021/10/05)
作者：Yang Tai, Chong Zhao, Linhao Zhang
期刊：Journal Of Cellular And Molecular Medicine
影響因子 ：5.300
引用產(chǎn)品：CL-0212
-
PI3K δ inhibitor PI-3065 induces apoptosis in hepatocellular carcinoma cells by targeting survivin(2023/01/06)
作者：Yuze Wei, Weiwei Ke, Zaiming Lu
期刊：CHEMICO-BIOLOGICAL INTERACTIONS
影響因子 ：5.100
-
Daphnetin inhibits the survival of hepatocellular carcinoma cells through regulating Wnt/β-catenin signaling pathway(2022/02/07)
作者：Chaohui Liu, Jiansheng Pan, Hongyu Liu
期刊：Drug Development Research
影響因子 ：5.004
-
Improving the antitumor efficiency against hepatocellular carcinoma by harmine-loaded liposomes with mitochondria targeting and legumain response(2022/08/01)
作者：Ipargul Hafiz, Zhezhe Li, Zhaozhi Wang
期刊：JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
DOI：10.1016/j.jddst.2022.103623
影響因子 ：5.000
引用產(chǎn)品：CL-0212
-
Pan-cancer analysis of 60S Ribosomal Protein L7-Like 1 (RPL7L1) and validation in liver hepatocellular carcinoma(2023/12/01)
作者：Kejie He, Guoyu Gong, E Liang
期刊：Translational Oncology
DOI：10.1016/j.tranon.2023.101844
影響因子 ：5.000
引用產(chǎn)品：CL-0212
-
Multimodal Theranostic Nanoparticles for Necrosis Targeting, Fluorescence/SPECT Imaging, and Radiotherapy of Residual Tumors after Hepatocellular Carcinoma Ablation(2024/03/07)
作者：Han Bao, Ning Wang, Song Chen
期刊：MOLECULAR PHARMACEUTICS
DOI：10.1021/acs.molpharmaceut.3c01081
影響因子 ：4.900
引用產(chǎn)品：CL-0212
-
The P53-P21-RB1 pathway promotes BRD4 degradation in liver cancer through USP1(2024/02/01)
作者：Neng Li, Erlei Zhang, Zhenyong Li
期刊：JOURNAL OF BIOLOGICAL CHEMISTRY
影響因子 ：4.800
引用產(chǎn)品：CL-0212
-
Tumor purity–associated genes influence hepatocellular carcinoma prognosis and tumor microenvironment(2023/06/26)
作者：Yan Zhao, Xu Xu, Yue Wang
期刊：Frontiers in Oncology
影響因子 ：4.700
-
System analysis based on the lysosome-related genes identifies HPS4 as a novel therapy target for liver hepatocellular carcinoma(2023/09/13)
作者：Kejie He, Zhiqiang Nie
期刊：Frontiers in Oncology
影響因子 ：4.700
-
Circ_0007429/miR-637/TRIM71/Ago2 axis participates in the regulation of proliferation, migration, invasion, apoptosis, and aerobic glycolysis of HCC(2023/03/15)
作者：Lilan Fan, Panpan Xia, Jing Wang
期刊：MOLECULAR CARCINOGENESIS
DOI：10.1002/mc.23526
影響因子 ：4.600
-
Humanized disulfide-stabilized diabody against fibroblast growth factor-2 inhibits PD-L1 expression and epithelial-mesenchymal transition in hepatoma cells through STAT3(2023/07/25)
作者：Huamin Sun, Xinran Song, Cunjie Li
期刊：IUBMB LIFE
DOI：10.1002/iub.2766
影響因子 ：4.600
-
Antipsychotic agent pimozide promotes reversible proliferative suppression by inducing cellular quiescence in liver cancer(2019/07/11)
作者：Jiajie Chen, Lina Zhang, Nan Cai
期刊：Oncology Reports
影響因子 ：4.200
引用產(chǎn)品：CL-0212
-
miR-10b-5p promotes tumor growth by regulating cell metabolism in liver cancer via targeting SLC38A2(2024/02/23)
作者：Mingzhi Xia, Jie Chen, Yingyun Hu
期刊：CANCER BIOLOGY & THERAPY
DOI：10.1080/15384047.2024.2315651
影響因子 ：3.600
引用產(chǎn)品：CL-0212
-
PAQR4 promotes the development of hepatocellular carcinoma by activating PI3K/AKT pathway(2021/10/30)
作者：Gang Zhao, Xiaobao Shi, Zhanbo Sun
期刊：Acta Biochimica Et Biophysica Sinica
影響因子 ：3.511
-
Long noncoding RNA HAND2-AS1 reduced the viability of hepatocellular carcinoma via targeting microRNA-300/SOCS5 axis(2020/03/12)
作者：Huaqiang Bi, Zhonghui Li, Hui Zhang
期刊：Hepatobiliary & Pancreatic Diseases International
DOI：10.1016/j.hbpd.2020.02.011.
影響因子 ：3.300
-
Lysine demethylase 5C epigenetically reduces transcription of ITIH1 that results in augmented progression of liver hepatocellular carcinoma(2022/01/25)
作者：Xu Qian, Zhongming Bao, Dan Yao
期刊：Kaohsiung Journal of Medical Sciences
影響因子 ：3.300
-
Identify GADD45G as a potential target of 4-methoxydalbergione in treatment of liver cancer: bioinformatics analysis and in vivo experiment(2023/10/13)
作者：Liping Zeng, Yuqi Qin, Xiaomin Lu
期刊：World Journal of Surgical Oncology
DOI：10.1186/s12957-023-03214-3
影響因子 ：3.200
引用產(chǎn)品：CL-0212
-
ZNF131 facilitates the growth of hepatocellular carcinoma by acting as a transcriptional activator of SMC4 expression(2024/01/11)
作者：Meng Jin, Yang Mi, Fazhan Li
期刊：BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
DOI：10.1016/j.bbrc.2024.149515
影響因子 ：3.100
引用產(chǎn)品：CL-0212
-
NFYAv1 is a Tumor-Promoting Transcript Associated with Poor Prognosis of Hepatocellular Carcinoma(2023/01/21)
作者：Zigang Li, Chengshan You, Jun Huang
期刊：MEDICAL SCIENCE MONITOR
影響因子 ：3.100
-
Prognostic and Immune Infiltration Analysis of Transaldolase 1 (TALDO1) in Hepatocellular Carcinoma(2023/12/31)
作者：Kedan Cen, Caide Lu
期刊：International Journal of General Medicine
影響因子 ：2.300
引用產(chǎn)品：CL-0212
-
Long non-coding RNA AK058003, as a precursor of miR-15a, interacts with HuR to inhibit the expression of Υ-synuclein in hepatocellular carcinoma cells(2016/12/27)
作者：Xiaoqin He, Yongfa Zheng, Yuefeng Zhang
期刊：Oncotarget
影響因子 ：0.000
FAQs
Q：{{item.question}}
A：
產(chǎn)品資料
識(shí)別碼示意圖
![CCRF-CEM [CCRF CEM] (人急性淋巴細(xì)胞白血病T淋巴細(xì)胞) (STR鑒定正確)](/Public/upfile/pic/xbx/CL-0058-1.jpg)
.png "梅文強(qiáng)")
