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產品概述
Dulbecco's 改良培養(yǎng)基--DMEM（Dulbecco's Modified Eagle Medium）是在MEM培養(yǎng)基的基礎上研制的，與MEM培養(yǎng)基相比，氨基酸的含量增加了2倍，維生素增加了4倍，同時還增加了非必須氨基酸、微量鐵離子以及丙酮酸鈉。DMEM培養(yǎng)基最初設計葡萄糖含量為1000mg/L（低糖型），后來又發(fā)展出葡萄糖含量為4500mg/L（高糖型），現(xiàn)已廣泛應用于各種細胞的培養(yǎng)，不含葡萄糖的DMEM培養(yǎng)基可以根據(jù)研究需要，隨意調節(jié)葡萄糖的濃度，方便快捷。
本產品含有多類細胞培養(yǎng)所需的氨基酸、維生素、無機鹽等多種成分，但不含蛋白質、脂類或任何生長因子，故此產品需搭配血清或無血清添加物使用。
成分說明
形態(tài) | 液體 |
濃度 | 1× |
規(guī)格 | 500mL |
PH | 7.2～7.4 |
L-谷氨酰胺 | 4mM |
NaHCO3 | 3700mg/L |
D-葡萄糖 | 無 |
丙酮酸鈉 | 1mM |
HEPES緩沖劑 | 無 |
酚紅指示劑 | 15mg/L |
儲存條件 | 2～8℃，避光 |
運輸條件 | 常溫 |
有效期 | 18個月 |
注意事項
1、本產品經過濾除菌，使用時應注意無菌操作，避免污染；
2、為保持本產品的最佳使用效果，請勿進行凍融處理；
3、本產品僅用于科研或進一步研究使用，不用于診斷和治療。
參考文獻
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Panax notoginseng saponins stimulates the differentiation and neurite development of C17.2 neural stem cells against OGD/R injuries via mTOR signaling(2024/02/21)
作者：Jiale Gao, Mingjiang Yao, Yehao Zhang
期刊：BIOMEDICINE & PHARMACOTHERAPY
DOI：10.1016/j.biopha.2024.116260
影響因子 ：7.500
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Polyphenolic Oligomer-Derived Multienzyme Activity for Treatment of Ischemic Stroke through ROS Scavenging and Blood-Brain Barrier Restoration(2024/01/24)
作者：Wei Meng, Zhifang Ma, Hongbo Ye
期刊：Journal of Materials Chemistry B
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Prenylated flavonoid fractions from Glycyrrhiza glabra alleviate insulin resistance in HepG2 cells by regulating the ERK/IRS-1 and PI3K/Akt signaling pathways(2024/01/24)
作者：Defeng Li, Jinling Fan, Lin Du
期刊：ARCHIVES OF PHARMACAL RESEARCH
DOI：10.1007/s12272-024-01485-2
影響因子 ：6.700
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Long non-coding RNA UCA1 relieves cardiomyocytes H9c2 injury aroused by oxygen-glucose deprivation via declining miR-122(2019/08/21)
作者：Zaiwei Zhang, Hu Li, Zhiyuan Cui
期刊：Artificial Cells Nanomedicine and Biotechnology
DOI：10.1080/21691401.2019.1652630
影響因子 ：5.800
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ALMS1-IT1: A Key Player in the Novel Disulfidptosis-Related LncRNA Prognostic Signature for Head and Neck Squamous Cell Carcinoma(2024/02/23)
作者：Xinyi Sun, Mian Xiao, Min Fu
期刊：Biomolecules
影響因子 ：5.500
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Inhibition of PDE1-B by Vinpocetine Regulates Microglial Exosomes and Polarization Through Enhancing Autophagic Flux for Neuroprotection Against Ischemic Stroke(2021/02/04)
作者：Jiankun Zang, Yousheng Wu, Xuanlin Su
期刊：Frontiers in Cell and Developmental Biology
影響因子 ：5.500
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Neutral polysaccharide from Gastrodia elata alleviates cerebral ischemia–reperfusion injury by inhibiting ferroptosis-mediated neuroinflammation via the NRF2/HO-1 signaling pathway(2023/09/26)
作者：Yonggang Zhang, Peng Ye, Hua Zhu
期刊：CNS Neuroscience & Therapeutics
影響因子 ：5.500
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TFE3-SLC36A1 axis promotes resistance to glucose starvation in kidney cancer cells(2024/04/08)
作者：Suli Lv, Zongbiao Zhang, Zhenyong Li
期刊：JOURNAL OF BIOLOGICAL CHEMISTRY
影響因子 ：4.800
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Pharmacological preconditioning by TERT inhibitor BIBR1532 confers neuronal ischemic tolerance through TERT-mediated transcriptional reprogramming(2021/10/09)
作者：Xuemin Xie, Mingxi Li, Mengyao Zhou
期刊：Journal Of Neurochemistry
影響因子 ：4.700
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Modified Citrus Pectin Alleviates Cerebral Ischemia/Reperfusion Injury by Inhibiting NLRP3 Inflammasome Activation via TLR4/NF-?B Signaling Pathway in Microglia(2022/09/17)
作者：Yu Cui, Nannan Zhang, Dan Wang
期刊：Journal of Inflammation Research
影響因子 ：4.631
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Oxysophoridine protects against cerebral ischemia/reperfusion injury via inhibition of TLR4/p38MAPK?mediated ferroptosis(2023/01/04)
作者：Jing Zhao, Mingming Ma, Lei Li
期刊：Molecular Medicine Reports
影響因子 ：3.400
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作者：Ran Chen, Hua Zhu, Zhihui Wang
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影響因子 ：3.300
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MiR-140-5p upregulation suppressed β-glycerophosphate-induced vascular smooth muscle cell calcification via targeting TLR4(2022/03/11)
作者：Fan Zhang,Jingxing Li,Chengxiong Gu
期刊：Immunopharmacology And Immunotoxicology
DOI：10.1080/08923973.2022.2043896
影響因子 ：3.300
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Fructose aggravates copper-deficiency-induced cardiac remodeling by inhibiting SERCA2a(2024/01/25)
作者：Yi Xu, Qiuxia Xu, Zhirui Zheng
期刊：JOURNAL OF PHARMACY AND PHARMACOLOGY
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作者：Xinyu Wang, Chao Yan, Chaoyun Wang
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Exosome-shuttled MYCBPAP from bone marrow mesenchymal stem cells regulates synaptic remodeling and ameliorates ischemic stroke in rats(2023/07/07)
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DOI：10.1016/j.jchemneu.2023.102309
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Inhibition of perilipin 2 attenuates cerebral ischemia/reperfusion injury by blocking NLRP3 inflammasome activation both in vivo and in vitro(2023/04/03)
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DOI：10.1007/s11626-023-00759-1
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期刊：NEUROREPORT
DOI：10.1097/WNR.0000000000001848
影響因子 ：1.700
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