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  • SH-SY5Y [SHSY-5Y] (人神經(jīng)母細(xì)胞瘤細(xì)胞) (STR鑒定正確)
  • SH-SY5Y [SHSY-5Y] (人神經(jīng)母細(xì)胞瘤細(xì)胞) (STR鑒定正確)
  • SH-SY5Y [SHSY-5Y] (人神經(jīng)母細(xì)胞瘤細(xì)胞) (STR鑒定正確)
  • SH-SY5Y [SHSY-5Y] (人神經(jīng)母細(xì)胞瘤細(xì)胞) (STR鑒定正確)
  • SH-SY5Y [SHSY-5Y] (人神經(jīng)母細(xì)胞瘤細(xì)胞) (STR鑒定正確)
  • SH-SY5Y [SHSY-5Y] (人神經(jīng)母細(xì)胞瘤細(xì)胞) (STR鑒定正確)
  • SH-SY5Y [SHSY-5Y] (人神經(jīng)母細(xì)胞瘤細(xì)胞) (STR鑒定正確)

SH-SY5Y [SHSY-5Y] (人神經(jīng)母細(xì)胞瘤細(xì)胞) (STR鑒定正確)

貨號:CL-0208

規(guī)格:1×10?cells/T25培養(yǎng)瓶

價(jià)格: ¥1600

生長培養(yǎng)基:SH-SY5Y [SHSY-5Y] 細(xì)胞專用培養(yǎng)基

數(shù)量: - +

  • SH-SY5Y [SHSY-5Y] (人神經(jīng)母細(xì)胞瘤細(xì)胞) (STR鑒定正確)
  • SH-SY5Y [SHSY-5Y] (人神經(jīng)母細(xì)胞瘤細(xì)胞) (STR鑒定正確)
  • SH-SY5Y [SHSY-5Y] (人神經(jīng)母細(xì)胞瘤細(xì)胞) (STR鑒定正確)
  • SH-SY5Y [SHSY-5Y] (人神經(jīng)母細(xì)胞瘤細(xì)胞) (STR鑒定正確)
  • SH-SY5Y [SHSY-5Y] (人神經(jīng)母細(xì)胞瘤細(xì)胞) (STR鑒定正確)
  • SH-SY5Y [SHSY-5Y] (人神經(jīng)母細(xì)胞瘤細(xì)胞) (STR鑒定正確)
  • SH-SY5Y [SHSY-5Y] (人神經(jīng)母細(xì)胞瘤細(xì)胞) (STR鑒定正確)

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SH-SY5Y [SHSY-5Y] (人神經(jīng)母細(xì)胞瘤細(xì)胞) (STR鑒定正確) ¥1600

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產(chǎn)品概述
產(chǎn)品信息
名稱 SH-SY5Y [SHSY-5Y] (人神經(jīng)母細(xì)胞瘤細(xì)胞) (STR鑒定正確)
別稱 SHSY5Y; SHSY-5Y; SH-Sy5y; SK-SH-SY5Y; SY5Y
種屬
生長特性 貼壁細(xì)胞,極少量懸浮
細(xì)胞形態(tài) 上皮細(xì)胞樣
凍存條件 凍存液:90%FBS+10%DMSO 溫度:液氮
培養(yǎng)方案A(默認(rèn))
培養(yǎng)條件:
氣相:空氣,95%;CO2,5%, 溫度:37℃
推薦傳代比例 1:3-1:4
推薦換液頻率 2-3次/周
注意事項(xiàng) 1.該細(xì)胞容易聚團(tuán),傳代第二天輕微聚團(tuán)甚至漂浮為正?,F(xiàn)象,無需換液繼續(xù)培養(yǎng)2~3天后細(xì)胞可正常貼壁;2.細(xì)胞聚團(tuán)嚴(yán)重影響細(xì)胞生長后,可用胰酶消化細(xì)胞使之重新分散,傳代后少動(dòng)少換液,聚團(tuán)會(huì)有改善。
參考資料(來源文獻(xiàn))
背景描述 SH-SY5Y細(xì)胞是于1970年建自骨瘤轉(zhuǎn)移灶的神經(jīng)母細(xì)胞瘤SK-N-SH細(xì)胞系經(jīng)3次克隆后的亞系(SK-N-SH→SH-SY→SH-SY5→SH-SY5Y)。SH-SY5Y細(xì)胞顯示中等水平的多巴胺-β-羥基酶活性,SH-SY5Y細(xì)胞的飽和密度大于1×10^6/cm^2。
年齡(性別) 女性;4歲
組織來源 腦神經(jīng)母細(xì)胞瘤,轉(zhuǎn)移部位骨髓
細(xì)胞類型 腫瘤細(xì)胞
腫瘤類型 神經(jīng)母細(xì)胞瘤細(xì)胞
生物安全等級 BSL-1
倍增時(shí)間 ~48-72 hours
抗原表達(dá)情況 Blood Type A; Rh+
保藏機(jī)構(gòu) ATCC; CRL-2266 DSMZ; ACC-209 ECACC; 94030304
STR鑒定
  • STR位點(diǎn)信息
    Amelogenin X
    CSF1PO 11
    D2S1338 17,19
    D3S1358 15,16
    D5S818 12
    D7S820 7,10
    D8S1179 15
    D13S317 11
    D16S539 8,13
    D18S51 13,16
    D19S433 13,14
    D21S11 31,31.2
    FGA 23.2,24
    PentaD 10,12
    PentaE 7,11
    TH01 7,10
    TPOX 8,11
    vWA 14,18
    D6S1043 12,18
    D12S391 18,22
    D2S441 11,11.3
  • STR鑒定圖
參考文獻(xiàn)
文獻(xiàn)列表
  • Exosome Heterogeneity Affects the Distal “Barrier-Crossing” Trafficking of Exosome Encapsulated Quantum Dots(2024/02/23)

    作者:Di Wu, Hang Sun, Bingwei Yang

    期刊:ACS Nano

    DOI:10.1021/acsnano.3c09378

    影響因子 :17.100

    引用產(chǎn)品:CL-0208

  • An artificial protein modulator reprogramming neuronal protein functions(2024/03/06)

    作者:Peihua Lin, Bo Zhang, Hongli Yang

    期刊:Nature Communications

    DOI:10.1038/s41467-024-46308-6

    影響因子 :16.600

    引用產(chǎn)品:CL-0208

  • A one-two punch targeting reactive oxygen species and fibril for rescuing Alzheimer’s disease(2024/01/24)

    作者:Jiefei Wang, Shangguan Ping, Xiaoyu Chen

    期刊:Nature Communications

    DOI:10.1038/s41467-024-44737-x

    影響因子 :16.600

    引用產(chǎn)品:CL-0208

  • Specific anti-glioma targeted-delivery strategy of engineered small extracellular vesicles dual-functionalised by Angiopep-2 and TAT peptides(2022/08/06)

    作者:Zhanchi Zhu, Yuanxin Zhai, Ying Hao

    期刊:Journal of Extracellular Vesicles

    DOI:10.1002/jev2.12255

    影響因子 :16.000

    引用產(chǎn)品:CL-0005 CL-0016 CL-0103 CL-0208 CL-0238 CL-0598

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    作者:Wenbo Ji, Honglei Zhou, Wendanqi Liang

    期刊:Small

    DOI:10.1002/smll.202308574

    影響因子 :13.300

    引用產(chǎn)品:CL-0208

  • Thioredoxin-1 inhibits the activation of IRE1 by targeting Hsp90/p-Cdc37 chaperone complex in Parkinson disease(2023/07/10)

    作者:Xiansi Zeng, Wenshuo Geng, Yu Zhang

    期刊:AGEING RESEARCH REVIEWS

    DOI:10.1016/j.arr.2023.102000

    影響因子 :13.100

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  • Inhibition of miR-331-3p and miR-9-5p ameliorates Alzheimers disease by enhancing autophagy(2021/01/01)

    作者:Menglu Chen, Chungu Hong, Tao Yue

    期刊:Theranostics

    DOI:10.7150/thno.47408

    影響因子 :12.400

    引用產(chǎn)品:CL-0208

  • Bone marrow mesenchymal stem cells loaded into hydrogel/nanofiber composite scaffolds ameliorate ischemic brain injury(2023/01/28)

    作者:Yanhong Pei, Lifei Huang, Tong Wang

    期刊:Materials Today Advances

    DOI:10.1016/j.mtadv.2023.100349

    影響因子 :10.000

    引用產(chǎn)品:CL-0208 CM-0208 CM-0675

  • A novel mitochondria-targeting DHODH inhibitor induces robust ferroptosis and alleviates immune suppression(2024/02/27)

    作者:Yongrui Hai, Renming Fan, Ting Zhao

    期刊:PHARMACOLOGICAL RESEARCH

    DOI:10.1016/j.phrs.2024.107115

    影響因子 :9.300

    引用產(chǎn)品:CL-0208

  • MAPKAPK2, a potential dynamic network biomarker of α-synuclein prior to its aggregation in PD patients(2023/03/16)

    作者:Zhenggang Zhong, Jiabao Li, Jiayuan Zhong

    期刊:npj Parkinsons Disease

    DOI:10.1038/s41531-023-00479-z

    影響因子 :8.700

    引用產(chǎn)品:CL-0208

  • Controllable mitochondrial aggregation and fusion by a programmable DNA binder(2023/07/06)

    作者:Longyi Zhu, Yiting Shen, Shengyuan Deng

    期刊:Chemical Science

    DOI:10.1039/D2SC07095B

    影響因子 :8.400

    引用產(chǎn)品:CL-0007 CL-0208

  • Modified acid polysaccharide derived from Salvia przewalskii with excellent wound healing and enhanced bioactivity(2024/01/30)

    作者:Kui Zhao, Cheng Qian, Luming Qi

    期刊:INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

    DOI:10.1016/j.ijbiomac.2024.129803

    影響因子 :8.200

    引用產(chǎn)品:CL-0208

  • Salvia miltiorrhiza Bge. processed with porcine cardiac blood inhibited GLRX5-mediated ferroptosis alleviating cerebral ischemia-reperfusion injury(2024/04/26)

    作者:Shikang Zhou, Ziqi Wang, Ting Wang

    期刊:PHYTOMEDICINE

    DOI:10.1016/j.phymed.2024.155622

    影響因子 :7.900

    引用產(chǎn)品:CL-0208

  • NTRK1-mediated protection against manganese-induced neurotoxicity and cell apoptosis via IGF2 in SH-SY5Y cells(2023/11/18)

    作者:Caixia Zhang, Bo Jiao, Xueqin Cao

    期刊:BIOMEDICINE & PHARMACOTHERAPY

    DOI:10.1016/j.biopha.2023.115889

    影響因子 :7.500

    引用產(chǎn)品:CL-0208

  • NIR-II light-activated two-photon squaric acid dye with Type I photodynamics for antitumor therapy(2022/10/24)

    作者:Kexin Wang, Yunjian Xu, Zhenjiang Chen

    期刊:Nanophotonics

    DOI:10.1515/nanoph-2022-0482

    影響因子 :7.500

    引用產(chǎn)品:CL-0208 PM150210

  • Nanosensor-Driven Detection of Neuron-Derived Exosomal Aβ42 with Graphene Electrolyte-Gated Transistor for Alzheimer’s Disease Diagnosis(2023/03/21)

    作者:Jiahao Li, Wei Ni, Dan Jin

    期刊:Analytical Chemistry

    DOI:10.1021/acs.analchem.2c05751

    影響因子 :7.400

    引用產(chǎn)品:CL-0208 CM-0208

  • Combined exposure to manganese and iron decreases oxidative stress-induced nerve damage by increasing Nrf2/HO-1/NQO1 expression(2023/12/20)

    作者:Yuanyuan Fang, Mengjun Teng, Jianchao Peng

    期刊:ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

    DOI:10.1016/j.ecoenv.2023.115853

    影響因子 :6.800

    引用產(chǎn)品:CL-0208

  • Cyfluthrin exposure during pregnancy causes neurotoxicity in offspring—Ca2+ overload via IP3R-GRP75-VDAC1 pathway(2024/03/15)

    作者:Haoxuan Gao, Mi Tian, Xiaozhe Geng

    期刊:ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

    DOI:10.1016/j.ecoenv.2024.116218

    影響因子 :6.800

    引用產(chǎn)品:CL-0208

  • Organic extracts in PM2.5 are the major triggers to induce ferroptosis in SH-SY5Y cells(2022/12/09)

    作者:CanCan Guo, Yi Lyu, ShuangShuang Xia

    期刊:ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

    DOI:10.1016/j.ecoenv.2022.114350

    影響因子 :6.800

    引用產(chǎn)品:164210 164210-50 CL-0208 PM151220

  • LncRNA TUG1 compromised neuronal mitophagy in cerebral ischemia/reperfusion injury by targeting sirtuin 1(2022/03/28)

    作者:LongXing Xue, SongFeng Chen, Shi-Xing Xue

    期刊:Cell Biology And Toxicology

    DOI:10.1007/s10565-022-09700-w

    影響因子 :6.100

    引用產(chǎn)品:CL-0208

  • Exendin-4 and linagliptin attenuate neuroinflammation in a mouse model of Parkinson’s disease(2022/11/09)

    作者:Haiyang Yu, Tong Sun, Zhen Wang

    期刊:Neural Regeneration Research

    DOI:10.4103/1673-5374.360242

    影響因子 :6.058

    引用產(chǎn)品:CL-0208

  • Chebulic Acid Prevents Hypoxia Insult via Nrf2/ARE Pathway in Ischemic Stroke(2022/12/19)

    作者:Rong Zhou, Kuan Lin, Changlong Leng

    期刊:Nutrients

    DOI:10.3390/nu14245390

    影響因子 :5.900

    引用產(chǎn)品:CL-0208

  • Vitamin K2 Modulates Mitochondrial Dysfunction Induced by 6-Hydroxydopamine in SH-SY5Y Cells via Mitochondrial Quality-Control Loop(2022/04/04)

    作者:Hengfang Tang, Zhiming Zheng, Han Wang

    期刊:Nutrients

    DOI:10.3390/nu14071504

    影響因子 :5.900

    引用產(chǎn)品:CL-0208

  • RVG29 Peptide-Modified Exosomes Loaded with Mir-133b Mediate the RhoA-ROCK Pathway to Improve Motor and Neurological Symptoms in Parkinson’s Disease(2024/04/05)

    作者:Peng Jiang, Yu Xiao, Xinmei Hu

    期刊:ACS Biomaterials Science & Engineering

    DOI:10.1021/acsbiomaterials.3c01622

    影響因子 :5.800

    引用產(chǎn)品:CL-0208

  • bub1 as a potential oncogene and a prognostic biomarker for neuroblastoma(2022/09/27)

    作者:Jingjing Song, Chao Ni, Xubin Dong

    期刊:Frontiers in Oncology

    DOI:10.3389/fonc.2022.988415

    影響因子 :5.738

    引用產(chǎn)品:CL-0208

  • Chemical Hypoxia Induces Pyroptosis in Neuronal Cells by Caspase-Dependent Gasdermin Activation(2024/02/11)

    作者:Chan Ho Park, Jun Young Park, Won Gil Cho

    期刊:INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

    DOI:10.3390/ijms25042185

    影響因子 :5.600

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  • The Relationship between Iron and LRRK2 in a 6-OHDA-Induced Parkinson’s Disease Model(2023/02/13)

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    期刊:INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

    DOI:10.3390/ijms24043709

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  • α-Synuclein Induces Neuroinflammation Injury through the IL6ST-AS/STAT3/HIF-1α Axis(2023/01/11)

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    期刊:INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

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    作者:Shuaiguang Li, Huarong Shao, Peixue Ling

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    DOI:10.3389/fphar.2024.1366683

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  • Cholestane-3β,5α,6β-triol Induces Multiple Cell Death in A549 Cells via ER Stress and Autophagy Activation(2024/04/13)

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    期刊:Bioengineered

    DOI:10.1080/21655979.2022.2042999

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