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產(chǎn)品概述
| 名稱 | CAL-62 (人甲狀腺癌細胞(未分化)) (STR鑒定正確) |
| 別稱 | Cal-62; CAL 62; Cal 62; CAL62; Centre Antoine Lacassagne-62 |
| 種屬 | 人 |
| 生長特性 | 貼壁細胞 |
| 細胞形態(tài) | 上皮細胞樣 |
| 凍存條件 | 凍存液：55% 基礎培養(yǎng)基+40%FBS+5%DMSO 溫度：液氮 |
| 培養(yǎng)方案A（默認） |
培養(yǎng)條件:
氣相：空氣，95%；CO2，5%, 溫度：37℃
|
| 推薦傳代比例 | 1:3-1:6 |
| 推薦換液頻率 | 2-3次/周 |
| 背景描述 | Established from the thyroid gland (right lobe) of a 70-year-old woman with thyroid anaplastic carcinoma in 1988; described as being tumorigenic in heterotransplanted nude mice |
| 年齡（性別） | 女性；70歲 |
| 組織來源 | 甲狀腺癌 |
| 細胞類型 | 腫瘤細胞 |
| 腫瘤類型 | 甲狀腺癌細胞 |
| 生物安全等級 | BSL-1 |
| 倍增時間 | ~24 hours (DSMZ) |
| 保藏機構(gòu) | DSMZ; ACC-448 |
STR鑒定
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STR位點信息
Amelogenin X CSF1PO 9,12 D2S1338 19,23 D3S1358 16 D5S818 9,12 D7S820 10 D8S1179 13 D13S317 12 D16S539 12,13 D18S51 16 D19S433 14 D21S11 32.2 FGA 19 PentaD 13 PentaE 5,10 TH01 7,9 TPOX 8,9 vWA 16 D6S1043 12 D12S391 22 D2S441 11 -
STR鑒定圖
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參考文獻
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RBX1 regulates PKM alternative splicing to facilitate anaplastic thyroid carcinoma metastasis and aerobic glycolysis by destroying the SMAR1/HDAC6 complex(2023/02/21)
作者：Xu Debin, Yu Jichun, Yang Yuting, Du Yunyan, Lu Hongcheng, Zhang Shouhua, Feng Qian, Yu Yi, Hao Liang, Shao Jun, Chen Leifeng
期刊：Cell and Bioscience
DOI：10.1186/s13578-023-00987-8
影響因子 ：7.500
引用產(chǎn)品：CL-0575 CL-0617 CL-0618 CL-0624 CL-0643 CL-0648 CL-0649
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Design, Synthesis, and Biological Evaluation of Potent and Selective PROTAC Degraders of Oncogenic KRASG12D(2024/01/10)
作者：Chuan Zhou, Zisheng Fan, Yuejiao Gu
期刊：JOURNAL OF MEDICINAL CHEMISTRY
DOI：10.1021/acs.jmedchem.3c01622
影響因子 ：7.300
引用產(chǎn)品：CL-0618
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Discovery of a Potent, Cooperative, and Selective SOS1 PROTAC ZZ151 with In Vivo Antitumor Efficacy in KRAS-Mutant Cancers(2023/03/10)
作者：Zehui Zhou, Guizhen Zhou, Chuan Zhou
期刊：JOURNAL OF MEDICINAL CHEMISTRY
DOI：10.1021/acs.jmedchem.3c00075
影響因子 ：7.300
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Pleckstrin homology and RhoGEF domain containing G4 (PLEKHG4) leads to the activation of RhoGTPases promoting the malignant phenotypes of thyroid cancer(2023/06/19)
作者：Qingling Yuan, Yuxia Fan, Zheng Liu
期刊：APOPTOSIS
DOI：10.1007/s10495-023-01861-1
影響因子 ：7.200
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Cytotoxic and Antibacterial Meroterpenoids Isolated from the Marine-Derived Fungus Talaromyces sp. M27416(2024/04/20)
作者：Lingzhi Tang, Jinmei Xia, Zhongwei Chen
期刊：Marine Drugs
影響因子 ：5.400
引用產(chǎn)品：CL-0618
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Anti-Anaplastic Thyroid Cancer (ATC) Effects and Mechanisms of PLX3397 (Pexidartinib), a Multi-Targeted Tyrosine Kinase Inhibitor (TKI)(2022/12/28)
作者：Jingtao Luo, Yun Wang, Lingkun Zhao
期刊：Cancers
影響因子 ：5.200
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Immunological characteristics of immunogenic cell death genes and malignant progression driving roles of TLR4 in anaplastic thyroid carcinoma(2023/11/21)
作者：Tong Xu, Chaozhuang Zhu, Feifeng Song
期刊：BMC CANCER
DOI：10.1186/s12885-023-11647-y
影響因子 ：3.800
引用產(chǎn)品：CL-0618
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Identification and Validation of Novel Genes in Anaplastic Thyroid Carcinoma via Bioinformatics Analysis(2023/01/30)
作者：Shengnan Wang, Jing Wu, Congcong Guo
期刊：Cancer Management and Research
影響因子 ：3.300
引用產(chǎn)品：CL-0618
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DNMT1/DNMT3a-mediated promoter hypermethylation and transcription activation of ICAM5 augments thyroid carcinoma progression(2024/01/17)
作者：Zanbin Li, Yong Ying, Xiangtai Zeng
期刊：FUNCTIONAL & INTEGRATIVE GENOMICS
DOI：10.1007/s10142-024-01293-3
影響因子 ：2.900
引用產(chǎn)品：CL-0618
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