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人臍靜脈內(nèi)皮細胞
Human Umbilical Vein Endothelial Cells
貨號：CP-H082
規(guī)格：5×10?Cells/T25培養(yǎng)瓶
價格： ￥6380
產(chǎn)品概述
人臍靜脈內(nèi)皮細胞
Cat NO.: CP-H082
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產(chǎn)品名稱：人臍靜脈內(nèi)皮細胞
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英文簡稱：UVECs
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組織來源：臍帶組織
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產(chǎn)品規(guī)格：5×105cells/T25細胞培養(yǎng)瓶
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細胞簡介：
人臍靜脈內(nèi)皮細胞分離自臍帶組織；它是臍靜脈的重要結構組成細胞之一，在機體的正常生理過程中發(fā)揮著重要作用。臍帶是哺乳類的連接胎兒和胎盤的管狀結構，臍帶中通過尿膜的血管即臍動脈和臍靜脈，卵黃囊的血管即臍腸系膜動脈及臍腸系膜靜脈。在子宮中，子宮動脈在胎盤的母體部分出的毛細血管，與胎盤的子體部胎兒毛細血管靠近，在此處母體和胎兒的血液間進行CO2和O2，代謝產(chǎn)物即代謝廢物和營養(yǎng)物質(zhì)的交換。臍動脈將胎兒產(chǎn)生的廢物運送至胎盤，臍靜脈將O2和營養(yǎng)物質(zhì)從胎盤運送給胎兒。
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方法簡介：
普諾賽實驗室分離的人臍靜脈內(nèi)皮細胞采用胰蛋白酶-膠原酶聯(lián)合消化法結合差速貼壁法、并通過內(nèi)皮細胞專用培養(yǎng)基培養(yǎng)篩選制備而來，細胞總量約為5×10?cells/瓶。
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質(zhì)量檢測：
普諾賽實驗室分離的人臍靜脈內(nèi)皮細胞經(jīng)CD31免疫熒光鑒定，純度可達90%以上，且不含有HIV-1、HBV、HCV、支原體、細菌、酵母和真菌等。
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培養(yǎng)信息：
包被條件 PLL(0.1mg/ml)，明膠(0.1%) 培養(yǎng)基 含F(xiàn)BS、生長添加劑、Penicillin、Streptomycin等 產(chǎn)品貨號 CM-H082 換液頻率 每2-3天換液一次 生長特性 貼壁 細胞形態(tài) 內(nèi)皮細胞樣 傳代特性 可傳3-5代左右；3代以內(nèi)狀態(tài)最佳 消化液 0.25%胰蛋白酶 培養(yǎng)條件 氣相：空氣，95%；CO2，5% 人臍靜脈內(nèi)皮細胞體外培養(yǎng)周期有限；建議使用普諾賽配套的專用生長培養(yǎng)基及正確的操作方法來培養(yǎng)，以此保證該細胞的最佳培養(yǎng)狀態(tài)。
產(chǎn)品手冊
參考文獻
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A peroxidase-like magneto-gold nanozyme AuNC@Fe3O4 with photothermal effect for induced cell apoptosis of hepatocellular carcinoma cells in vitro(2023/03/23)
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Hydrogen sulfide regulates macrophage polarization and necroptosis to accelerate diabetic skin wound healing(2024/04/03)
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iNOS inhibitor S-methylisothiourea alleviates smoke inhalation-induced acute lung injury by suppressing inflammation and macrophage infiltration(2023/11/20)
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TRPC6 Deletion Enhances eNOS Expression and Reduces LPS—Induced Acute Lung Injury(2023/11/25)
作者：Mengyuan Wang, Xingfang Zhang, Juan Guo
期刊：INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
影響因子 ：5.600
引用產(chǎn)品：CP-H082
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Sialic acids promote macrophage M1 polarization and atherosclerosis by upregulating ROS and autophagy blockage(2023/06/03)
作者：Xuemei Hu, Yueyue Li, Qingyang Chen
期刊：INTERNATIONAL IMMUNOPHARMACOLOGY
DOI：10.1016/j.intimp.2023.110410
影響因子 ：5.600
-
LncRNA SNHG15 relieves hyperglycemia-induced endothelial dysfunction via increased ubiquitination of thioredoxin-interacting protein(2021/06/08)
作者：Qianqian Zhu, Mingchun Lai, Tianchi Chen
期刊：Laboratory Investigation
DOI：10.1038/s41374-021-00614-5
影響因子 ：5.502
引用產(chǎn)品：CP-H082
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Functionalized Periodic Mesoporous Silica Nanoparticles for Inhibiting the Progression of Atherosclerosis by Targeting Low-Density Lipoprotein Cholesterol(2024/01/04)
作者：Hao Jin, Wenbin Lu, Yahao Zhang
期刊：Pharmaceutics
DOI：10.3390/pharmaceutics16010074
影響因子 ：5.400
引用產(chǎn)品：CP-H082
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Epidermal Growth Factor‐Like Repeats and Discoidin I‐Like Domains 3 Deficiency Attenuates Dilated Cardiomyopathy by Inhibiting Ubiquitin Specific Peptidase 10 Dependent Smad4 Deubiquitination(2024/03/08)
作者：Mengmeng Zhao, Zihui Zheng, Shanshan Peng
期刊：Journal of the American Heart Association
影響因子 ：5.400
引用產(chǎn)品：CP-H082
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Non-Invasive and Label-Free On-Chip Impedance Monitoring of Heatstroke(2023/06/27)
作者：Yueli Zhao, Weihua Fan, Anwei Liu
期刊：Biosensors-Basel
影響因子 ：5.400
-
Macrophage-derived exosomal miR-4532 promotes endothelial cells injury by targeting SP1 and NF-κB P65 signalling activation(2022/09/07)
作者：Peng Liu, Shuya Wang, Guangxin Wang
期刊：JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
影響因子 ：5.300
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Asiaticoside Attenuates Blood–Spinal Cord Barrier Disruption by Inhibiting Endoplasmic Reticulum Stress in Pericytes After Spinal Cord Injury(2023/09/01)
作者：Zhenxin Hu, Tingting Wu, Ziheng Zhou
期刊：MOLECULAR NEUROBIOLOGY
DOI：10.1007/s12035-023-03605-3
影響因子 ：5.100
引用產(chǎn)品：CP-H082
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Silencing of long chain noncoding RNA paternally expressed gene (PEG10) inhibits the progression of neuroblastoma by regulating microRNA-449a (miR-449a)/ribosomal protein S2 (RPS2) axis(2022/02/25)
作者：Jian Zhang, Wei Liu, Ping Ji
期刊：Bioengineered
DOI：10.1080/21655979.2022.2042999
影響因子 ：4.900
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Nano?/micro-scaled hydroxyapatite ceramic construction and the regulation of immune-associated osteogenic differentiation(2023/09/08)
作者：Shijia Fu, Huishan Li, Yue Wu
期刊：JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
影響因子 ：4.900
引用產(chǎn)品：CP-H082
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MicroRNA-140-3p represses the proliferation, migration, invasion and angiogenesis of lung adenocarcinoma cells via targeting TYMS (thymidylate synthetase)(2021/12/16)
作者：Shanzhi Wan, Zhimin Liu, Yang Chen
期刊：Bioengineered
DOI：10.1080/21655979.2021.2009422
影響因子 ：4.900
引用產(chǎn)品：CP-H082
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Endothelial CYP2J2 overexpression restores the BRB via METTL3-mediated ANXA1 upregulation(2022/10/21)
作者：Bowen Zhao, Jingqiu Huang, Xiaotong Lou
期刊：FASEB JOURNAL
影響因子 ：4.800
-
An Autophagy-Associated MITF–GAS5–miR-23 Loop Attenuates Vascular Oxidative and Inflammatory Damage in Sepsis(2023/06/24)
作者：Junning Cheng, Chang Ding, Huying Tang
期刊：Biomedicines
DOI：10.3390/biomedicines11071811
影響因子 ：4.700
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Composite Hydrogel Containting Collagen-Modified Polylactic Acid-hydroxylactic acid Copolymer Microspheres Loaded with Tetramethylpyrazine Promotes Articular Cartilage Repair(2024/04/10)
作者：Yalan Pan, Bin Li, Xiaoxian Sun
期刊：MACROMOLECULAR BIOSCIENCE
影響因子 ：4.600
引用產(chǎn)品：CP-H082
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Microfluidics-Based Fabrication of Cell-Laden Hydrogel Microfibers for Potential Applications in Tissue Engineering(2019/04/25)
作者：Gen Wang, Luanluan Jia, Fengxuan Han
期刊：Molecules
影響因子 ：4.600
引用產(chǎn)品：CP-H082
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Butylated hydroxyanisole induces vascular endothelial injury via TFEB-mediated degradation of GPX4 and FTH1(2024/04/22)
作者：Yufei Zhan, Yazhuo Zhang
期刊：FOOD AND CHEMICAL TOXICOLOGY
影響因子 ：4.300
引用產(chǎn)品：CP-H082
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LncRNA FGF7-5 and lncRNA GLRX3 together inhibits the formation of carotid plaque via regulating the miR-2681-5p/ERCC4 axis in atherosclerosis(2022/09/07)
作者：Jianjin Wu, Jie Jin, Yonghua Li
期刊：CELL CYCLE
DOI：10.1080/15384101.2022.2110446
影響因子 ：4.300
引用產(chǎn)品：CP-H082
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MicroRNA-9 rescues hyperglycemia-induced endothelial cell dysfunction and promotes arteriogenesis through downregulating Notch1 signaling(2021/3/15)
作者：Huang Chen, Zhihai Feng, Lieyou Li
期刊：Molecular And Cellular Biochemistry
DOI：10.1007/s11010-021-04075-8
影響因子 ：4.300
引用產(chǎn)品：CP-H082
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Polyethylenimine Triggers Dll4 Degradation to Regulate Angiogenesis In Vitro(2024/02/07)
作者：Binghua Cheng, Yanyan Li, Yabin Ji
期刊：ACS Omega
影響因子 ：4.100
引用產(chǎn)品：CP-H082
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ADAR1 is targeted by miR-143 to regulate IL-1β-induced endothelial activation through the NFκB pathway(2017/5/17)
作者：Yuanzhuo Chen, Hu Peng, Shuqin Zhou
期刊：International Journal Of Biochemistry & Cell Biology
DOI：10.1016/j.biocel.2017.05.021
影響因子 ：4.000
-
Exosome-derived miR-23a-5p inhibits HCC proliferation and angiogenesis by regulating PRDX2 expression: MiR-23a-5p/PRDX2 axis in HCC progression.(2023/12/02)
作者：Yang Zhao, Jun Liu, Zhengping Xiong
期刊：Heliyon
DOI：10.1016/j.heliyon.2023.e23168
影響因子 ：4.000
引用產(chǎn)品：CP-H082
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M2 macrophage-derived exosomes induce angiogenesis and increase skin flap survival through HIF1AN/HIF-1α/VEGFA control(2023/11/27)
作者：Gaojie Luo, Zekun Zhou, Zheming Cao
期刊：ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
影響因子 ：3.900
引用產(chǎn)品：CP-H082
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Interfering with Dusp2 alleviates high glucose-induced vascular endothelial cell dysfunction by promoting p38 MAPK pathway activation(2023/07/20)
作者：Xinmiao Jiang, Qiong Yan, Jiaqi He
期刊：EXPERIMENTAL CELL RESEARCH
DOI：10.1016/j.yexcr.2023.113720
影響因子 ：3.700
引用產(chǎn)品：CP-H082
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DNMT3A-mediated epigenetic silencing of SOX17 contributes to endothelial cell migration and fibroblast activation in wound healing(2023/10/19)
作者：Xiaoping Yu, Xiaoting Ma, Junli Zhou
期刊：PLoS One
DOI：10.1371/journal.pone.0292684
影響因子 ：3.700
引用產(chǎn)品：CP-H082
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PCSK9 inhibitor inclisiran for treating atherosclerosis via regulation of endothelial cell pyroptosis(2022/11/01)
作者：Ni Kong, Qin Xu, Wei Cui
期刊：Annals of Translational Medicine
影響因子 ：3.616
引用產(chǎn)品：CP-H082
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Curcumin suppresses the malignant phenotype of laryngeal squamous cell carcinoma through downregulating E2F1 to inhibit FLNA(2024/04/09)
作者：Yuanchun Xie, Jingjing Qi, Ju Liu
期刊：NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
DOI：10.1007/s00210-024-03059-x
影響因子 ：3.600
引用產(chǎn)品：CP-H082
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Reduction of renal interstitial fibrosis by targeting Tie2 in vascular endothelial cells(2023/11/27)
作者：Lu Jiang, Xiaohan Hu, Yajun Feng
期刊：PEDIATRIC RESEARCH
DOI：10.1038/s41390-023-02893-8
影響因子 ：3.600
引用產(chǎn)品：CP-H082
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Cytoprotective effects of C1s enzyme in macrophages in atherosclerosis mediated through the LRP5 and Wnt/β-catenin pathway(2024/01/12)
作者：Dong Yuan, Zhipeng Zheng, Cheng Shen
期刊：MOLECULAR IMMUNOLOGY
DOI：10.1016/j.molimm.2024.01.002
影響因子 ：3.600
引用產(chǎn)品：CP-H082
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Synergistic anti-tumour activity of ginsenoside Rg3 and doxorubicin on proliferation, metastasis and angiogenesis in osteosarcoma by modulating mTOR/HIF-1α/VEGF and EMT signalling pathways(2023/07/27)
作者：Xiangfeng Zeng, Shengyao Liu, Hua Yang
期刊：JOURNAL OF PHARMACY AND PHARMACOLOGY
影響因子 ：3.300
引用產(chǎn)品：CP-H082
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Regulation of Atherosclerosis by Toll-Like Receptor 4 Induced by Serum Amyloid 1: A Systematic In Vitro Study.(2022/09/15)
作者：Jinhui Chen, Gang Liu, Yan Hong
期刊：Biomed Research International
影響因子 ：3.246
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Melatonin inhibits the formation of intraplaque neovessels in ApoE?/? mice via PPARγ- RhoA-ROCK pathway(2023/12/28)
作者：YuFan Jiang, Wei Tong, Yueyang Li
期刊：BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
DOI：10.1016/j.bbrc.2023.149391
影響因子 ：3.100
引用產(chǎn)品：CP-H082
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Bioactive self-healing umbilical cord blood exosomes hydrogel for promoting chronic diabetic wound healing(2023/11/11)
作者：Kexin Liu, Benxin Gong, Tao Li
期刊：BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
DOI：10.1016/j.bbrc.2023.149241
影響因子 ：3.100
引用產(chǎn)品：CP-H082
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Dulaglutide restores endothelial progenitor cell levels in diabetic mice and mitigates high glucose-induced endothelial injury through SIRT1-mediated mitochondrial fission(2024/04/25)
作者：Xi Mei, Yao Li, Jinlin Wu
期刊：BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
DOI：10.1016/j.bbrc.2024.150002
影響因子 ：3.100
引用產(chǎn)品：CP-H082
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Quercetin alleviates hyperoxia-induced bronchopulmonary dysplasia by inhibiting ferroptosis through the MAPK/PTGS2 pathway: Insights from network pharmacology, molecular docking, and experimental evaluations(2024/04/03)
作者：Xianhui Deng, Dan Chen, Anni Xie
期刊：Chemical Biology & Drug Design
影響因子 ：3.000
引用產(chǎn)品：CP-H082
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Flavonoid Compounds in? Hippophae rhamnoides? L.?Protect Endothelial Cells from Oxidative Damage Through the?PI3K/AKT-eNOS?Pathway(2024/03/02)
作者：Mengyuan Wang, Xingfang Zhang, Zonghao Zhang
期刊：CHEMISTRY & BIODIVERSITY
影響因子 ：2.900
引用產(chǎn)品：CP-H082
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Interleukin?6 released by oral lichen planus myofibroblasts promotes angiogenesis(2021/01/27)
作者：Xiaoheng Xu, Yang Liu, Lu Feng
期刊：Experimental and Therapeutic Medicine
影響因子 ：2.700
引用產(chǎn)品：CP-H082
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DNTTIP2 Expression is Associated with Macrophage Infiltration and Malignant Characteristics in Low-Grade Glioma(2022/11/19)
作者：Yuanjie Liu, Shuhong Zeng, Weihua Qian
期刊：Pharmacogenomics & Personalized Medicine
影響因子 ：2.606
引用產(chǎn)品：CP-H082
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Gastrodin Suppresses the Progression of Atherosclerosis and Vascular Inflammation by Regulating TLR4/NF‐κB Pathway(2024/01/25)
作者：Bing Dai, Cunfa Liu, Song Zhang
期刊：CELL BIOCHEMISTRY AND BIOPHYSICS
DOI：10.1007/s12013-024-01218-8
影響因子 ：2.600
引用產(chǎn)品：CP-H082
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Exploring the application of sildenafil for high-fat diet-induced erectile dysfunction based on interleukin-18-mediated NLRP3/Caspase-1 signaling pathway(2023/08/25)
作者：Bingbing Zhu, Yangjiu Niu, Lipan Niu
期刊：Sexual Medicine
影響因子 ：2.600
引用產(chǎn)品：CP-H082
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Circular RNA (circ)_0053277 Contributes to Colorectal Cancer Cell Growth, Angiogenesis, Metastasis and Glycolysis(2023/11/02)
作者：Jianbin Zhuang, Weiliang Song, Minghao Li
期刊：MOLECULAR BIOTECHNOLOGY
DOI：10.1007/s12033-023-00936-3
影響因子 ：2.600
引用產(chǎn)品：CP-H082
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Curcumin Inhibits the Progression of Non-small Cell Lung Cancer by Regulating DMRT3/SLC7A11 Axis(2024/05/14)
作者：Bin Xu, Li Zhou, Qian Zhang
期刊：MOLECULAR BIOTECHNOLOGY
DOI：10.1007/s12033-024-01166-x
影響因子 ：2.600
引用產(chǎn)品：CP-H082
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NREP is a Diagnostic and Prognostic Biomarker, and Promotes Gastric Cancer Cell Proliferation and Angiogenesis(2022/09/12)
作者：Qian Li, Lei Fu, Daoyuan Wu
期刊：BIOCHEMICAL GENETICS
DOI：10.1007/s10528-022-10276-7
影響因子 ：2.400
-
Circular RNA circCHSY1 silencing inhibits the malignant progression of esophageal squamous cell carcinoma(2024/03/21)
作者：Haiquan He, Ying Chen, Hanping Liang
期刊：Discover Oncology
DOI：10.1007/s12672-024-00935-z
影響因子 ：2.200
引用產(chǎn)品：CP-H082
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Hsa_circ_0048674 facilitates hepatocellular carcinoma progression and natural killer cell exhaustion depending on the regulation of miR-223-3p/PDL1(2022/12/01)
作者：Suihui Li, Zhuangzhong Chen, Ruisheng Zhou
期刊：HISTOLOGY AND HISTOPATHOLOGY
影響因子 ：2.130
引用產(chǎn)品：CP-H082
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Knockdown of circ_0004585 enhances the chemosensitivity of colorectal cancer cells to 5-fluorouracil via the miR-874-3p/CCND1 axis(2023/01/01)
作者：Shijie Wang, Juan Cao, Lijuan Pei
期刊：HISTOLOGY AND HISTOPATHOLOGY
影響因子 ：2.000
引用產(chǎn)品：CP-H082
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Kelp Fucoidans Facilitate Vascular Recanalization via Inhibiting Excessive Activation of Platelet in Deep Venous Thrombosis Model of Mouse(2024/04/01)
作者：Taohua Sun, Jie Liu, Taishan Yan
期刊：Journal of Ocean University of China
影響因子 ：1.600
引用產(chǎn)品：CP-H082
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The effects of propranolol on the biology and Notch signaling pathway of human umbilical vein endothelial cells(2023/08/11)
作者：Shuming Chen, Xuekai Zhao, Junjie Huang
期刊：MEDICINE
DOI：10.1097/MD.0000000000034672
影響因子 ：1.600
引用產(chǎn)品：CP-H082
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Comparative Analysis of the Anti-Inflammatory Effects of Liraglutide and Dulaglutide(2024/05/15)
作者：Yi Hou, Yini Fan, Yuan Cheng
期刊：International Heart Journal
影響因子 ：1.500
引用產(chǎn)品：CP-H082
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Fabrication of co-polymeric nanoformulation loaded with antibiotic ofloxacin and immunosuppressant tacrolimus for pediatric sepsis-induced acute lung injury(2023/07/01)
作者：Shuang Yuan, Dai Qian, Wanyun Su
期刊：Materials Express
影響因子 ：0.700
引用產(chǎn)品：CP-H082
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