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產(chǎn)品概述
名稱 | MM.1S (人多發(fā)性骨髓瘤細(xì)胞) (STR鑒定正確) |
別稱 | MM.1S; MM1-S; MM-1S; MM1S |
種屬 | 人 |
生長(zhǎng)特性 | 半貼半懸 |
細(xì)胞形態(tài) | 圓形細(xì)胞 |
凍存條件 | 凍存液:55% 基礎(chǔ)培養(yǎng)基+40%FBS+5%DMSO 溫度:液氮 |
培養(yǎng)方案A(默認(rèn)) |
培養(yǎng)條件:
氣相:空氣,95%;CO2,5%, 溫度:37℃
|
推薦傳代比例 | 1:2-1:4 |
推薦換液頻率 | 2-3次/周 |
背景描述 | The parent cell line, MM.1, was established from peripheral blood of a multiple myeloma patient who had become resistant to steroid-based therapy. The closely related cell line, MM.1R was also isolated from MM.1, but is resistant to dexamethasone. |
年齡(性別) | 女性;45歲 |
組織來(lái)源 | 外周血 |
細(xì)胞類型 | 腫瘤細(xì)胞 |
腫瘤類型 | 骨髓瘤細(xì)胞 |
生物安全等級(jí) | BSL-1 |
倍增時(shí)間 | 80 hours (PubMed=25984343) |
受體表達(dá)情況 | glucocorticoid receptor, expressed |
抗原表達(dá)情況 | CD25+, CD38+, CD52+, CD59+ |
基因表達(dá)情況 | lambda-light chain immunoglobulin |
保藏機(jī)構(gòu) | ATCC; CRL-2974 |
STR鑒定
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STR位點(diǎn)信息
Amelogenin X CSF1PO 9,14 D2S1338 21,22 D3S1358 16,17 D5S818 8,12 D7S820 10,11 D8S1179 14 D13S317 13 D16S539 12 D18S51 11,16 D19S433 13 D21S11 29,30 FGA 20,24 PentaD 2.2,9 PentaE 13,15 TH01 7,8 TPOX 8 vWA 15,17 D6S1043 14,19 D12S391 17,24 D2S441 11 -
STR鑒定圖
參考文獻(xiàn)
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Synthesis and bioactivity evaluation of ferrocene-based hydroxamic acids as selective histone deacetylase 6 inhibitors(2022/12/07)
作者:Jiangkun Yan, Kairui Yue, Xuejing Fan
期刊:EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
DOI:10.1016/j.ejmech.2022.115004
影響因子 :6.700
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