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產(chǎn)品概述
| 名稱 | A172 (人膠質母細胞瘤細胞) (STR鑒定正確) |
| 別稱 | A172; A 172; A-172 MG; A-172MG |
| 種屬 | 人 |
| 生長特性 | 貼壁細胞 |
| 細胞形態(tài) | 成纖維細胞樣 |
| 凍存條件 | 凍存液：55% 基礎培養(yǎng)基+40%FBS+5%DMSO 溫度：液氮 |
| 培養(yǎng)方案A（默認） |
培養(yǎng)條件:
氣相：空氣，95%；CO2，5%, 溫度：37℃
|
| 推薦傳代比例 | 1:3-1:4 |
| 推薦換液頻率 | 2-3次/周 |
| 背景描述 | A172細胞在半固體培養(yǎng)基中可形成克??；A172細胞在免疫抑制小鼠中不成瘤。 |
| 年齡（性別） | 男性；53歲 |
| 組織來源 | 腦；膠質母細胞瘤 |
| 細胞類型 | 腫瘤細胞 |
| 腫瘤類型 | 膠質瘤細胞 |
| 生物安全等級 | BSL-1 |
| 倍增時間 | ~40 hours |
| 致瘤性 | No, the cells were not tumorigenic in immunosuppressed mice.Yes, form colonies in semisolid medium. |
| 保藏機構 | ATCC; CRL-1620 ATCC; CRL-7899ECACC; 88062428 |
STR鑒定
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STR位點信息
Amelogenin X,Y CSF1PO 9,12 D2S1338 20,21 D3S1358 14,18 D5S818 11,12 D7S820 11 D8S1179 13,14 D13S317 11 D16S539 12 D18S51 12,13 D19S433 12,15.2 D21S11 28,32.2 FGA 20,22 PentaD 9,13 PentaE 5,10 TH01 6,9.3 TPOX 8,11 vWA 20 D6S1043 13,18 D12S391 22 D2S441 10,11 -
STR鑒定圖
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參考文獻
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Chitinase-3 like-protein-1 promotes glioma progression via the NF-κB signaling pathway and tumor microenvironment reprogramming.(2022/10/03)
作者：Ting Zhao, Jianming Zeng, Yujie Xu
期刊：Theranostics
影響因子 ：12.400
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Identification of pimavanserin tartrate as a potent Ca2+-calcineurin-NFAT pathway inhibitor for glioblastoma therapy(2021/08/06)
作者：Zhenzhen Liu, Xiaoning Liu, Ruicheng Fan
期刊：Acta Pharmacologica Sinica
DOI：10.1038/s41401-021-00724-2
影響因子 ：8.200
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Overexpression of GINS4 is associated with poor prognosis and survival in glioma patients(2021/09/23)
作者：Binfeng Liu, Zhendong Liu, Yanbiao Wang
期刊：Molecular Medicine
DOI：10.1186/s10020-021-00378-0
影響因子 ：5.700
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Overexpressed XRCC2 as an independent risk factor for poor prognosis in glioma patients(2021/05/29)
作者：Zhendong Liu, Wang Zhang, Xingbo Cheng
期刊：Molecular Medicine
DOI：10.1186/s10020-021-00316-0
影響因子 ：5.700
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Nifuroxazide inhibits the growth of glioblastoma and promotes the infiltration of CD8 T cells to enhance antitumour immunity(2023/03/14)
作者：Xinzhuang Wang, Junyi Ye, Ming Gao
期刊：INTERNATIONAL IMMUNOPHARMACOLOGY
DOI：10.1016/j.intimp.2023.109987
影響因子 ：5.600
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RNA-binding protein DHX9 promotes glioma growth and tumor-associated macrophages infiltration via TCF12(2022/11/15)
作者：Liang Liu, Xuelan Zhou, Shan Cheng, Yuyuan Ge, Baomin Chen, Jia Shi, Haoran Li, Suwen Li, Yongdong Li, Jiaqi Yuan, Anyi Wu, Xinglei Liu, Shilu Huang, Zhipeng Xu, Jun Dong
期刊：CNS Neuroscience & Therapeutics
影響因子 ：5.500
引用產(chǎn)品：CL-0012 CL-0233 CL-0237 CL-0458 CL-0578 CL-0583 CP-H122
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ITGB3BP is a potential biomarker associated with poor prognosis of glioma( 2021/12/24)
作者：Zhendong Liu, Binfeng Liu, Lu Bian
期刊：Journal of Cellular and Molecular Medicine
影響因子 ：5.300
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Knockdown of PGBD5 inhibits the malignant progression of glioma through upregulation of the PPAR pathway(2024/04/05)
作者：Pengren Luo, Jinhong Yang, Lipeng Jian
期刊：INTERNATIONAL JOURNAL OF ONCOLOGY
影響因子 ：5.200
引用產(chǎn)品：CL-0012
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YTHDF1 promotes the viability and self?renewal of glioma stem cells by enhancing LINC00900 stability(2024/03/28)
作者：Yuanhai Zhang, Yi Zhu, Yating Zhang
期刊：INTERNATIONAL JOURNAL OF ONCOLOGY
影響因子 ：5.200
引用產(chǎn)品：CL-0012
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DNA Damage-Induced Apoptosis Suppressor Triggers Progression and Stemness of Glioma by Enhancing Lymphoid Enhancer-Binding Factor 1 Expression(2024/03/21)
作者：Youlin Chen, Yi Liu, Yan Xu
期刊：World Journal of Oncology
影響因子 ：5.200
引用產(chǎn)品：CL-0012
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Lemur tyrosine kinase 2 has a tumor-inhibition function in human glioblastoma by regulating the RUNX3/Notch pathway(2023/06/02)
作者：Lei Zhang, Peng Luo, Xinggang Mao
期刊：BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
DOI：10.1016/j.bbamcr.2023.119509
影響因子 ：5.100
引用產(chǎn)品：164210-50 CL-0012 CL-0237 CL-0238 CL-0458 CL-0583 PB180120 PM150210 PM150410
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GD2 CAR-T cells in combination with Nivolumab exhibit enhanced antitumor efficacy(2023/03/24)
作者：Guangji Zhang, Yu Zhao, Zhongfeng Liu
期刊：Translational Oncology
DOI：10.1016/j.tranon.2023.101663
影響因子 ：5.000
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CKAP4-mediated activation of FOXM1 via phosphorylation pathways regulates malignant behavior of glioblastoma cells(2023/01/24)
作者：Kaiyue Xu, Kaiqian Zhang, Jiying Ma
期刊：Translational Oncology
DOI：10.1016/j.tranon.2023.101628
影響因子 ：5.000
引用產(chǎn)品：CL-0012
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Sevoflurane inhibits progression of glioma via regulating the HMMR antisense RNA 1/microRNA-7/cyclin dependent kinase 4 axis(2021/8/31)
作者：Xian Bao, Yibo Peng, Jun Shen
期刊：Bioengineered
DOI：10.1080/21655979.2021.1976712
影響因子 ：4.900
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A novel hypoxia-driven gene signature that can predict the prognosis and drug resistance of gliomas.(2022/09/02)
作者：Peng Ren, Jingya Wang, Zhirui Zeng
期刊：Frontiers in Genetics
影響因子 ：4.772
引用產(chǎn)品：CL-0012
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β3GNT9 as a prognostic biomarker in glioblastoma and its association with glioblastoma immune infiltration, migration and invasion(2023/09/12)
作者：YingHao Luo, Kan Wang, Lu Zhan
期刊：Frontiers in Oncology
影響因子 ：4.700
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Prognostic Significance of mRNA Expression RBBP8 or Its Methylation in Gliomas(2022/02/01)
作者：Zhendong Liu, Xingbo Cheng, Shaochong Lin
期刊：Cellular And Molecular Neurobiology
DOI：10.1007/s10571-022-01198-4
影響因子 ：4.231
引用產(chǎn)品：CL-0012
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Inhibition of FAM83D displays antitumor effects in glioblastoma via down-regulation of the AKT/Wnt/β-catenin pathway(2022/02/12)
作者：Jubo Wang, Yu Quan, Jian Lv
期刊：Environmental Toxicology
影響因子 ：4.109
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Phospholipid scramblase 1 acts through the IL-6/JAK/STAT3 pathway to promote the malignant progression of glioma(2024/04/16)
作者：ShiZhen Zhou, Jun Xu, YuFang Zhu
期刊：ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
影響因子 ：3.900
引用產(chǎn)品：CL-0012
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CircCDC45 promotes the malignant progression of glioblastoma by modulating the miR-485-5p/CSF-1 axis(2021/10/09)
作者：Rongcai Liu, Weimin Dai, An Wu
期刊：Bmc Cancer
DOI：10.1186/s12885-021-08803-7
影響因子 ：3.800
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CircRNA circ_POSTN promotes the malignancy of glioma by regulating the miR-433-3p/SPARC axis(2022/12/01)
作者：Xiangting Hua, Chaoyong Zhang, Yongfeng Ba
期刊：METABOLIC BRAIN DISEASE
DOI：10.1007/s11011-022-01126-x
影響因子 ：3.600
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EIF4A3-induced circCCNB1 (hsa_circ_0001495) promotes glioma progression by elevating CCND1 through interacting miR-516b-5p and HuR(2022/01/17)
作者：Xiaoli Li, Chengmou Wang, Guanghui Chen
期刊： Metabolic Brain Disease
DOI：10.1007/s11011-021-00899-x
影響因子 ：3.600
引用產(chǎn)品：164210 CL-0012 CL-0237 CL-0238 CL-0583 PB180120 PM150210
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Circular RNA circ_0000741/miR-379-5p/TRIM14 signaling axis promotes HDAC inhibitor (SAHA) tolerance in glioblastoma(2023/03/11)
作者：Liang Meng, Yuefei Wang, Qin Tu
期刊：METABOLIC BRAIN DISEASE
DOI：10.1007/s11011-023-01184-9
影響因子 ：3.600
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Hsa_circ_0043949 reinforces temozolomide resistance via upregulating oncogene ITGA1 axis in glioblastoma(2022/10/27)
作者：Xuzhao Li, Nianhua Wang, Haibin Leng
期刊：METABOLIC BRAIN DISEASE
DOI：10.1007/s11011-022-01069-3
影響因子 ：3.600
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Circular RNA circ_0001588 sponges miR-211-5p to facilitate the progression of glioblastoma via up-regulating YY1 expression(2021/07/14)
作者：Qian Wang, Dahai Zheng, Yuhan Li
期刊：Journal Of Gene Medicine
DOI：10.1002/jgm.3371
影響因子 ：3.500
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Bioinformatics Analysis and Experimental Validation for Exploring Key Molecular Markers for Glioblastoma(2024/03/06)
作者：Zhenchao Huang, Zhijie Chen, En’peng Song
期刊：APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
DOI：10.1007/s12010-024-04894-7
影響因子 ：3.000
引用產(chǎn)品：CL-0012
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PSMC2 promotes glioma progression by regulating immune microenvironment and PI3K/AKT/mTOR pathway(2024/03/30)
作者：Yizheng Wang, Shiyang Zhang, Zijun Zhao
期刊：IMMUNOBIOLOGY
DOI：10.1016/j.imbio.2024.152802
影響因子 ：2.800
引用產(chǎn)品：CL-0012
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Tumor-promoting function of PIMREG in glioma by activating the β-catenin pathway(2021/7/23)
作者：Dekang?Wang, Aili Hu, Hao Peng
期刊：3 BIOTECH
DOI：10.1007/s13205-021-02922-5
影響因子 ：2.800
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Low Expression of GRM4 Is Associated with Poor Prognosis and Tumor Immune Infiltration in Glioma(2023/12/19)
作者：Hai Fan, Dongming Yan, Xingyue Fang
期刊：INTERNATIONAL JOURNAL OF NEUROSCIENCE
DOI：10.1080/00207454.2023.2297646
影響因子 ：2.200
引用產(chǎn)品：CL-0012
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Silibinin suppresses glioblastoma cell growth, invasion, stemness, and glutamine metabolism by YY1/SLC1A5 pathway(2024/02/24)
作者：Ming Liu, Xipeng Liu, Jianxin Qiao
期刊：Translational Neuroscience
影響因子 ：2.100
引用產(chǎn)品：CL-0012
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識別碼示意圖
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