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C-33 A (人子宮頸癌細胞) (STR鑒定正確)
貨號：CL-0045
規(guī)格：1×10?cells/T25培養(yǎng)瓶
價格： ￥1600
生長培養(yǎng)基：MEM（含NEAA）＋10% FBS＋1% P/S
產(chǎn)品概述
| 名稱 | C-33 A (人子宮頸癌細胞) (STR鑒定正確) |
| 別稱 | C33A; C33a; C33-A; C-33-A; C-33A; C33 |
| 種屬 | 人 |
| 生長特性 | 貼壁細胞 |
| 細胞形態(tài) | 上皮細胞樣 |
| 凍存條件 | 凍存液：55% 基礎(chǔ)培養(yǎng)基+40%FBS+5%DMSO 溫度：液氮 |
| 培養(yǎng)方案A（默認） |
生長培養(yǎng)基:
培養(yǎng)條件:
氣相：空氣，95%；CO2，5%, 溫度：37℃
|
| 推薦傳代比例 | 1:3-1:4 |
| 推薦換液頻率 | 2-3次/周 |
| 背景描述 | C-33 A細胞是由N·Auersperg從宮頸癌切片中建立的一系列細胞株中的一株。C-33 A細胞一開始就表現(xiàn)出亞二倍體核型及上皮細胞形態(tài)，C-33 A細胞經(jīng)連續(xù)傳代可以觀察到核型不穩(wěn)定。C-33 A細胞存在成視網(wǎng)膜細胞瘤蛋白(pRB)，但大小不正常；C-33 A細胞p53表達上調(diào)，且有一個273位密碼子的點突變導致Arg→Cys的替換。 |
| 年齡（性別） | 女性；66歲 |
| 組織來源 | 宮頸癌 |
| 細胞類型 | 腫瘤細胞 |
| 腫瘤類型 | 宮頸癌細胞 |
| 生物安全等級 | BSL-1 |
| 倍增時間 | ~32-48 hours |
| 保藏機構(gòu) | ATCC; HTB-31 ATCC; CRM-HTB-31 BCRC; 60554 BCRJ; 0348 |
STR鑒定
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STR位點信息
Amelogenin X CSF1PO 12 D2S1338 23,25 D3S1358 16 D5S818 11,12 D7S820 10 D8S1179 10,14 D13S317 13 D16S539 13,14 D18S51 15,18 D19S433 11,13,14 D21S11 29,30,31 FGA 21,26 PentaD 10 PentaE 6,8 TH01 7,8 TPOX 9 vWA 18,20 D6S1043 9,11,12 D12S391 18,27 D2S441 10,14 -
STR鑒定圖
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參考文獻
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Design of Selective PARP-1 Inhibitors and Antitumor Studies(2024/05/22)
作者：Yiting Zhang, Xiangqian Li, Fang Liu
期刊：JOURNAL OF MEDICINAL CHEMISTRY
DOI：10.1021/acs.jmedchem.3c02460
影響因子 ：7.300
引用產(chǎn)品：CL-0045
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Acetylation-stabilized chloride intracellular channel 1 exerts a tumor-promoting effect on cervical cancer cells by activating NF-κB(2021/01/19)
作者：Wanyue Wang, Xin Li, Ye Xu
期刊：Cellular Oncology
DOI：10.1007/s13402-020-00582-w
影響因子 ：6.600
-
3-Hydroxymorindone from Knoxia roxburghii (Spreng.) M. A. Rau induces ROS-mediated mitochondrial dysfunction cervical cancer cells apoptosis via inhibition of PI3K/AKT/NF-κB signaling pathway(2023/03/11)
作者：Xiaojiao Chen, Zhibo Liu, Xue Li
期刊：Journal of Functional Foods
影響因子 ：5.600
-
Marine Sulfated Polysaccharide PMGS Synergizes with Paclitaxel in Inhibiting Cervical Cancer In Vitro(2023/04/23)
作者：Xuan Xia, Yanhong Wang, Yingchun Shao
期刊：Marine Drugs
影響因子 ：5.400
-
Kinetochore-associated protein 1 promotes the invasion and tumorigenicity of cervical cancer cells via matrix metalloproteinase-2 and matrix metalloproteinase-9(2022/04/07)
作者：Caimei Wang, Yiyuan Wang, Congrong Liu
期刊：Bioengineered
DOI：10.1080/21655979.2022.2061144
影響因子 ：4.900
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Combined treatment of marizomib and cisplatin modulates cervical cancer growth and invasion and enhances antitumor potential in vitro and in vivo(2022/08/30)
作者：Ziruizhuo Zhang, Songcheng Zhang, Bingjie Lin
期刊：Frontiers in Oncology
影響因子 ：4.700
引用產(chǎn)品：CL-0045
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USP21 regulates Hippo signaling to promote radioresistance by deubiquitinating FOXM1 in cervical cancer(2021/11/25)
作者：Zhengliang Li , Xiaojing Liu , Haizhou Yu
期刊：Human Cell
DOI：10.1007/s13577-021-00650-9
影響因子 ：4.300
-
OTX1 promotes tumorigenesis and progression of cervical cancer by regulating the Wnt signaling pathway(2022/09/29)
作者：Limin Zhou, Hongying Li, Dunlan Zhang
期刊：ONCOLOGY REPORTS
影響因子 ：4.200
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HPV16+-miRNAs in cervical cancer and the anti-tumor role played by miR-5701(2019/10/25)
作者：Nuerbieke Pulati,?Zegao Zhang,?Aireti Gulimilamu
期刊：Journal Of Gene Medicine
DOI：10.1002/jgm.3126
影響因子 ：4.152
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HPV16 E6 promoting cervical cancer progression through down-regulation of miR-320a to increase TOP2A expression(2024/01/11)
作者：Jianing Zhang, Xiaohui Yu, Yi Guo
期刊：Cancer Medicine
影響因子 ：4.000
引用產(chǎn)品：CL-0045
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APLN promotes the proliferation, migration, and glycolysis of cervical cancer through the PI3K/AKT/mTOR pathway(2024/03/30)
作者：Qi Wang, Bingyu Wang, Wenjing Zhang
期刊：ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
影響因子 ：3.900
引用產(chǎn)品：CL-0045
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Increased TCP11 gene expression can inhibit the proliferation, migration and promote apoptosis of cervical cancer cells(2023/09/11)
作者：Fang Wang, Shuyan Song, Bingxuan Guo
期刊：BMC CANCER
DOI：10.1186/s12885-023-11129-1
影響因子 ：3.800
引用產(chǎn)品：CL-0045
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Characterization of the microenvironment in different immune-metabolism subtypes of cervical cancer with prognostic significance(2023/02/03)
作者：Wujiang Lai, Jinrong Liao, Xiaoxuan Li
期刊：Frontiers in Genetics
DOI：10.3389/fgene.2023.1067666
影響因子 ：3.700
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Signature of seven cuproptosis-related lncRNAs as a novel biomarker to predict prognosis and therapeutic response in cervical cancer.(2022/09/20)
作者：Xinyu Liu, Lei Zhou, Minghui Gao
期刊：Frontiers in Genetics
影響因子 ：3.700
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The degradation of Rap1GAP via E6AP-mediated ubiquitin-proteasome pathway is associated with HPV16/18-infection in cervical cancer cells(2021/12/24)
作者：Yinghui Wang, Yihang Xie, Boxuan Sun
期刊：Infectious Agents and Cancer
DOI：10.1186/s13027-021-00409-9
影響因子 ：3.700
引用產(chǎn)品：CL-0045
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Hypoxic tumor cell-derived small extracellular vesicle miR-152-3p promotes cervical cancer radioresistance through KLF15 protein(2023/11/07)
作者：Junying Zhou, Ningjing Lei, Wanjia Tian
期刊：Radiation Oncology
DOI：10.1186/s13014-023-02369-3
影響因子 ：3.600
引用產(chǎn)品：CL-0045
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Inhibition of miR-574-5p suppresses cell growth and metastasis and enhances chemosensitivity by targeting RNA binding protein QKI in cervical cancer cells(2019/11/30)
作者：Rui Tong, Jingru Zhang, Chunyan Wang
期刊：Naunyn-Schmiedebergs Archives of Pharmacology
DOI：10.1007/s00210-019-01772-6
影響因子 ：3.600
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Norcantharidin inhibits the malignant progression of cervical cancer by inducing endoplasmic reticulum stress(2024/03/07)
作者：Zhongbao Zhang, Beibei Sun, Jinqiu Lu
期刊：Molecular Medicine Reports
影響因子 ：3.400
引用產(chǎn)品：CL-0045
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hsa_circ_0119412 overexpression promotes cervical cancer progression by targeting miR-217 to upregulate anterior gradient 2(2022/03/11)
作者：Yumei Lv,?Mingyi Wang,?Mingli Chen
期刊：Journal Of Clinical Laboratory Analysis
影響因子 ：3.124
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Transcription factor Dp-1 knockdown downregulates thymidine kinase 1 expression to protect against proliferation and epithelial-mesenchymal transition in cervical cancer(2023/09/16)
作者：Mei Wu, Mingji Ye
期刊：FUNCTIONAL & INTEGRATIVE GENOMICS
DOI：10.1007/s10142-023-01218-6
影響因子 ：2.900
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LncRNA PTCSC3 inhibits the proliferation, invasion and migration of cervical cancer cells via sponging miR‐574‐5p(2019/10/06)
作者：Rui Tong,?Jingru Zhang,?Chunyan Wang
期刊：Clinical And Experimental Pharmacology And Physiology
影響因子 ：2.900
引用產(chǎn)品：CL-0045
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SHCBP1 contributes to the proliferation and self?renewal of cervical cancer cells and activation of the NF?κB signaling pathway through EIF5A(2023/04/21)
作者：Boya Deng, Ailin Li, Ying Zhu
期刊：Oncology Letters
影響因子 ：2.900
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N6-methyladenosine methylation on FSCN1 mediated by METTL14/IGF2BP3 contributes to human papillomavirus type 16-infected cervical squamous cell carcinoma(2024/04/28)
作者：Qingqing Tian, Juqing Huang, Qin Zhang
期刊：CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
影響因子 ：2.900
引用產(chǎn)品：CL-0045
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Expression of GMFB in High-Grade Cervical Intraepithelial Neoplasia and Its Role in Cervical Cancer(2022/09/22)
作者：Jun Tian, Jianqing Wang, Yinxiu Chi
期刊：Computational and Mathematical Methods in Medicine
影響因子 ：2.809
引用產(chǎn)品：CL-0045
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FBXO39 predicts poor prognosis and correlates with tumor progression in cervical squamous cell carcinoma(2022/08/28)
作者：Yanru Yang, Yun Zhao, Guorui Sun
期刊：PATHOLOGY RESEARCH AND PRACTICE
影響因子 ：2.800
-
TRIM21 promotes tumor progression and cancer stemness in cervical squamous cell carcinoma(2023/07/23)
作者：Yanru Yang, Saijie Zuo, Wenqing Li
期刊：PATHOLOGY RESEARCH AND PRACTICE
影響因子 ：2.800
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CLCA2 overexpression suppresses epithelial-to-mesenchymal transition in cervical cancer cells through inactivation of ERK/JNK/p38-MAPK signaling pathways(2022/10/25)
作者：Wenhu Xin, Jian Zhang, Haibin Zhang
期刊：BMC Molecular and Cell Biology
DOI：10.1186/s12860-022-00440-7
影響因子 ：2.800
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ZIC5 promotes aggressiveness and cancer stemness in cervical squamous cell carcinoma(2022/12/05)
作者：Qingge Jia, Junyang Song, Tianqi Xu
期刊：PATHOLOGY RESEARCH AND PRACTICE
影響因子 ：2.800
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Cellular Retinoic Acid Binding Protein 2 (CRABP2), Up-regulated by HPV E6/E7, Leads to Aberrant Activation of the Integrin β1/FAK/ERK Signaling Pathway and Aggravates the Malignant Phenotypes of Cervical Cancer(2023/11/24)
作者：Jiaxin Liu, Lu Tang, Wenzhu Chu
期刊：BIOCHEMICAL GENETICS
DOI：10.1007/s10528-023-10568-6
影響因子 ：2.400
引用產(chǎn)品：CL-0045
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PLAC8 contributes to the malignant behaviors of cervical cancer cells by activating the SOX4-mediated AKT pathway(2023/01/05)
作者：Boya Deng, Siyang Zhang, Yingying Zhou
期刊：HISTOCHEMISTRY AND CELL BIOLOGY
DOI：10.1007/s00418-022-02175-0
影響因子 ：2.300
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MiR-1299 is regulated by KCNQ1OT1 and inhibits cervical cancer progression(2023/10/31)
作者：Qian Yang, Jing Fu, Min Wang
期刊：CELLULAR AND MOLECULAR BIOLOGY
DOI：10.14715/cmb/2023.69.10.24
影響因子 ：1.600
引用產(chǎn)品：CL-0045
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