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ES-2 (人卵巢透明細(xì)胞癌細(xì)胞) (STR鑒定正確)
貨號：CL-0079
規(guī)格：1×10?cells/T25培養(yǎng)瓶
價格： ￥1600
生長培養(yǎng)基：McCoy’s 5A＋10% FBS＋1% P/S
產(chǎn)品概述
| 名稱 | ES-2 (人卵巢透明細(xì)胞癌細(xì)胞) (STR鑒定正確) |
| 別稱 | ES2 |
| 種屬 | 人 |
| 生長特性 | 貼壁細(xì)胞 |
| 細(xì)胞形態(tài) | 成纖維細(xì)胞樣 |
| 凍存條件 | 凍存液：55% 基礎(chǔ)培養(yǎng)基+40%FBS+5%DMSO 溫度：液氮 |
| 培養(yǎng)方案A（默認(rèn)） |
生長培養(yǎng)基:
培養(yǎng)條件:
氣相：空氣，95%；CO2，5%, 溫度：37℃
|
| 推薦傳代比例 | 1:3-1:4 |
| 推薦換液頻率 | 2-3次/周 |
| 背景描述 | ES-2細(xì)胞是建自45歲女性黑人的外科腫瘤標(biāo)本，該腫瘤為低分化卵巢透明細(xì)胞癌。ES-2細(xì)胞最初生長在軟瓊脂中；ES-2細(xì)胞在裸鼠中成瘤。ES-2細(xì)胞對多種化療藥物包括阿霉素、順鉑、卡氯芥、依托泊甙等表現(xiàn)出低到中等的耐受性；ES-2細(xì)胞表達(dá)低水平的P糖蛋白。 |
| 年齡（性別） | 女性；47歲 |
| 組織來源 | 透明細(xì)胞癌，卵巢 |
| 細(xì)胞類型 | 腫瘤細(xì)胞 |
| 腫瘤類型 | 卵巢癌細(xì)胞 |
| 生物安全等級 | BSL-1 |
| 倍增時間 | ~28-36 hours |
| 致瘤性 | Yes, tumors developed within 21 days at 100% frequency (5/5) in nude mice inoculated subcutaneously with 1×10^7 cells. |
| 基因表達(dá)情況 | P glycoprotein |
| 保藏機(jī)構(gòu) | ATCC; CRL-1978 BCRC; 60067 BCRJ; 0080 |
STR鑒定
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STR位點(diǎn)信息
Amelogenin X CSF1PO 10,15 D2S1338 17,23 D3S1358 15,18 D5S818 11,13 D7S820 11 D8S1179 14 D13S317 11 D16S539 11,13 D18S51 13,15 D19S433 15,15.2 D21S11 32.2,33.2 FGA 21 PentaD 8,13 PentaE 13,16 TH01 9.3 TPOX 8,12 vWA 16,17 D6S1043 11,12 D12S391 20,21 D2S441 11 -
STR鑒定圖
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參考文獻(xiàn)
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BNC1 deficiency-triggered ferroptosis through the NF2-YAP pathway induces primary ovarian insufficiency(2022/10/05)
作者：Feixia Wang, Yifeng Liu, Feida Ni
期刊：Nature Communications
DOI：10.1038/s41467-022-33323-8
影響因子 ：16.600
引用產(chǎn)品：CL-0079
-
MiR-337–3p suppresses proliferation of epithelial ovarian cancer bytargeting PIK3CA and PIK3CB(2019/10/17)
作者：Zhen Zhang, Luoyan Zhang, Bin Wang
期刊：Cancer Letters
DOI：10.1016/j.canlet.2019.10.021
影響因子 ：9.700
-
GSK3β and UCHL3 govern RIPK4 homeostasis via deubiquitination to enhance tumor metastasis in ovarian cancer(2024/04/25)
作者：Wulin Shan, Wenju Peng, Yao Chen
期刊：ONCOGENE
DOI：10.1038/s41388-024-03040-1
影響因子 ：8.000
引用產(chǎn)品：CL-0079
-
Tumor-secreted anterior gradient-2 binds to VEGF and FGF2 and enhances their activities by promoting their homodimerization(2017/05/08)
作者：H Guo, Q Zhu, X Yu
期刊：Oncogene
影響因子 ：8.000
-
Suppressive activities of mangiferin on human epithelial ovarian cancer(2020/06/15)
作者：Zheng Zeng, Caiji Lin, Siwen Wang
期刊：Phytomedicine
DOI：10.1016/j.phymed.2020.153267
影響因子 ：7.900
引用產(chǎn)品：CL-0079
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Naringenin suppresses epithelial ovarian cancer by inhibiting proliferation and modulating gut microbiota(2022/08/19)
作者：Caiji Lin, Zheng Zeng, Yiru Lin
期刊：PHYTOMEDICINE
DOI：10.1016/j.phymed.2022.154401
影響因子 ：7.900
引用產(chǎn)品：CL-0079
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ZSWIM4 inhibition improves chemosensitivity in epithelial ovarian cancer cells by suppressing intracellular glycine biosynthesis(2024/02/21)
作者：Kunxiang Gong, Yinger Huang, Yanqin Zheng
期刊：Journal of Translational Medicine
DOI：10.1186/s12967-024-04980-8
影響因子 ：7.400
引用產(chǎn)品：CL-0079
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Enterolactone and trabectedin suppress epithelial ovarian cancer synergistically via upregulating THBS1(2023/07/13)
作者：Zheng Zeng, Caiji Lin, Mengchun Zhang
期刊：PHYTOTHERAPY RESEARCH
DOI：10.1002/ptr.7942
影響因子 ：7.200
引用產(chǎn)品：CL-0079
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Cannabidiol Inhibits Epithelial Ovarian Cancer: Role of Gut Microbiome(2024/04/11)
作者：Danli Cao, Yiru Lin, Caiji Lin
期刊：JOURNAL OF NATURAL PRODUCTS
DOI：10.1021/acs.jnatprod.3c00782
影響因子 ：5.100
引用產(chǎn)品：CL-0079
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Overexpression of IGF2BP3 as a Potential Oncogene in Ovarian Clear Cell Carcinoma(2020/01/30)
作者：Huidi Liu, Zheng Zeng , Mitra Afsharpad
期刊：Frontiers in Oncology
影響因子 ：4.700
引用產(chǎn)品：CL-0079
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MiR-29c downregulates tumor-expressed B7-H3 to mediate the antitumor NK-cell functions in ovarian cancer(2021/04/17)
作者：Mengqi Deng, Di Wu, Yanqin Zhang
期刊：Gynecologic Oncology
DOI：10.1016/j.ygyno.2021.04.013
影響因子 ：4.700
-
The roles of autophagy, ferroptosis and pyroptosis in the anti-ovarian cancer mechanism of harmine and their crosstalk(2024/03/18)
作者：Jun Zhu, Hong Zhu, Qing Zhu
期刊：Scientific Reports
DOI：10.1038/s41598-024-57196-7
影響因子 ：4.600
引用產(chǎn)品：CL-0079
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Down-regulation of lncRNA BLACAT1 inhibits ovarian cancer progression by suppressing the Wnt/β-catenin signaling pathway via regulating miR-519d-3p(2020/2/24)
作者：Hua Yang, Yue Qi, Xinlu Wang
期刊：MOLECULAR AND CELLULAR BIOCHEMISTRY
DOI：10.1007/s11010-020-03704-y.?
影響因子 ：4.300
引用產(chǎn)品：CL-0079
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Knockdown of heat shock protein family D member 1 (HSPD1) promotes proliferation and migration of ovarian cancer cells via disrupting the stability of mitochondrial 3-oxoacyl-ACP synthase (OXSM)(2023/04/22)
作者：Yaoyun Duan, Juan Yu, Miaojuan Chen
期刊：Journal of Ovarian Research
DOI：10.1186/s13048-023-01156-8
影響因子 ：4.000
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Enterolactone has stronger effects than enterodiol on ovarian cancer(2017/7/24)
作者：Liu Huidi, Liu Jianrui, Wang Siwen
期刊：Journal of Ovarian Research
影響因子 ：4.000
引用產(chǎn)品：CL-0079
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RNA-binding protein IGF2BP2 enhances circ_0000745 abundancy and promotes aggressiveness and stemness of ovarian cancer cells via the microRNA-3187-3p/ERBB4/PI3K/AKT axis(2021/11/13)
作者：Shengtan Wang, Zaihong Li , Genhai Zhu
期刊：Journal of Ovarian Research
DOI：10.1186/s13048-021-00917-7
影響因子 ：4.000
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Main components of pomegranate, ellagic acid and luteolin, inhibit metastasis of ovarian cancer by down-regulating MMP2 and MMP9(2017/11/27)
作者：Huidi Liu, Zheng Zeng, Siwen Wang
期刊：Cancer Biology & Therapy
DOI：10.1080/15384047.2017.1394542
影響因子 ：3.600
引用產(chǎn)品：CL-0079
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miR?638 suppresses proliferation by negatively regulating high mobility group?A1 in ovarian cancer cells(2021/9/20)
作者：Li Ma, Wei Zhang, Yaofeng Jin
期刊：Experimental and Therapeutic Medicine
影響因子 ：2.700
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CCNB1, Negatively Regulated by miR-559, Promotes the Proliferation, Migration, and Invasion of Ovarian Carcinoma Cells(2022/03/09)
作者：Xiaowen Yang, Shilin Zhou, Chunyue Yang
期刊：Molecular Biotechnology
DOI：10.1007/s12033-022-00463-7
影響因子 ：2.600
引用產(chǎn)品：CL-0079
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Circ_0021573 acts as a competing endogenous RNA to promote the malignant phenotypes of human ovarian cancer cells(2022/12/05)
作者：Lifang Liu, Bingkai Han, Lixia Liu
期刊：Reproductive Biology
DOI：10.1016/j.repbio.2022.100704
影響因子 ：2.100
引用產(chǎn)品：164210 164210-50 CL-0005 CL-0079 CL-0178 CL-0215 PB180120 PM150110
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PHGDH Inhibitor CBR-5884 Inhibits Epithelial Ovarian Cancer Progression via ROS/Wnt/β-Catenin Pathway and Plays a Synergistic Role with PARP Inhibitor Olaparib(2022/09/05)
作者：Xiaocui Zhang, Meige Sun, Yisheng Jiao
期刊：Oxidative Medicine and Cellular Longevity
影響因子 ：0.000
引用產(chǎn)品：164210 164210-50 CL-0079 CL-0178 PM150110 PM150710
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