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![HCT-8 [HRT-18] (人回盲腸癌細(xì)胞) (STR鑒定正確)](/Public/upfile/pic/xbx/CL-0098-1-1.jpg)
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產(chǎn)品概述
| 名稱 | HCT-8 [HRT-18] (人回盲腸癌細(xì)胞) (STR鑒定正確) |
| 別稱 | HCT-8; HCT8 |
| 種屬 | 人 |
| 生長特性 | 貼壁細(xì)胞 |
| 細(xì)胞形態(tài) | 上皮細(xì)胞樣 |
| 凍存條件 | 凍存液：55% 基礎(chǔ)培養(yǎng)基+40%FBS+5%DMSO 溫度：液氮 |
| 培養(yǎng)方案A（默認(rèn)） |
培養(yǎng)條件:
氣相：空氣，95%；CO2，5%, 溫度：37℃
|
| 推薦傳代比例 | 1:3-1:4 |
| 推薦換液頻率 | 2-3次/周 |
| 背景描述 | HCT-8 [HRT-18]細(xì)胞與HRT-18細(xì)胞是一樣的；角蛋白免疫過氧化物酶染色陽性。 |
| 年齡（性別） | 男性；67歲 |
| 組織來源 | 結(jié)腸；回盲腸結(jié)直腸腺癌 |
| 細(xì)胞類型 | 腫瘤細(xì)胞 |
| 腫瘤類型 | 腸癌細(xì)胞 |
| 生物安全等級(jí) | BSL-1 |
| 致瘤性 | Yes, in nude mice(Tumors developed within 21 days at 100% frequency (5/5) in nude mice inoculated subcutaneously with 1×10^8 cells). |
| 基因表達(dá)情況 | carcinoembryonic antigen (CEA) 0.5 ng/10^6 cells/10 days; alkaline phosphatase. The cells are positive for keratin by immunoperoxidase staining. |
| 保藏機(jī)構(gòu) | ECACC; 90032006 |
STR鑒定
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STR位點(diǎn)信息
Amelogenin X CSF1PO 12 D2S1338 17,25 D3S1358 17 D5S818 13 D7S820 10,11.3 D8S1179 15 D13S317 8,11 D16S539 12,13 D18S51 11,17 D19S433 14,16 D21S11 29,32.2 FGA 22 PentaD 9,14 PentaE 7,14 TH01 7,9.3 TPOX 8,11 vWA 18,19 D6S1043 11,13 D12S391 19,22 D2S441 13,15 -
STR鑒定圖
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參考文獻(xiàn)
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Engineering redirected NF-κB/OIP5 expression programs to enhance tumor responses to chemotherapy in bladder cancer(2023/11/14)
作者：Binbin Zheng, Liman Niu, Haibo Xu
期刊：Science Bulletin
DOI：10.1016/j.scib.2023.11.027
影響因子 ：18.900
引用產(chǎn)品：CL-0098
-
Blockade of the deubiquitinating enzyme USP48 degrades oncogenic HMGA2 and inhibits colorectal cancer invasion and metastasis(2024/01/17)
作者：Can Cheng, Hanhui Yao, Heng Li
期刊：Acta Pharmaceutica Sinica B
DOI：10.1016/j.apsb.2024.01.006
影響因子 ：14.500
引用產(chǎn)品：CL-0098
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The feedback loop of ANKHD1/lncRNA MALAT1/YAP1 strengthens the radioresistance of CRC by activating YAP1/AKT signaling(2022/02/02)
作者：Pingan Yao, Yong Wu , Kui Zhao
期刊：Cell Death & Disease
DOI：10.1038/s41419-022-04554-w
影響因子 ：9.000
-
Discovery of a nitroaromatic nannocystin with potent in vivo anticancer activity against colorectal cancer by targeting AKT1(2024/02/07)
作者：Han Zhang, Fei Xie, Xiaoya Yuan
期刊：ACTA PHARMACOLOGICA SINICA
DOI：10.1038/s41401-024-01231-w
影響因子 ：8.200
引用產(chǎn)品：CL-0098
-
The Active Fraction of Polyrhachis vicina Roger (AFPR) activates ERK to cause necroptosis in colorectal cancer(2023/04/12)
作者：Dongmei Li, Fucui Zhu, Jie Wei
期刊：JOURNAL OF ETHNOPHARMACOLOGY
影響因子 ：5.400
引用產(chǎn)品：CL-0098
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Aureusidin derivative CNQX inhibits chronic colitis inflammation and mucosal barrier damage by targeting myeloid differentiation 2 protein(2021/07/11)
作者：Yi Yang, Yongjia Sheng, Jin Wang
期刊：Journal Of Cellular And Molecular Medicine
影響因子 ：5.300
引用產(chǎn)品：CL-0098
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Overexpression of ZNF169 promotes the growth and proliferation of colorectal cancer cells via the upregulation of ANKZF1(2024/04/23)
作者：Jie Zhang, Ye Wang, Shiyang Hou
期刊：ONCOLOGY REPORTS
影響因子 ：4.200
引用產(chǎn)品：CL-0098
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Site-directed Late-Stage Diversification of Macrocyclic Nannocystins Facilitating Anticancer SAR and Mode of Action Studies(2022/12/22)
作者：Han Zhang, Yunfeng Tian, Xiaoya Yuan
期刊：RSC Medicinal Chemistry
影響因子 ：4.100
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NSUN6 mediates 5-methylcytosine modification of METTL3 and promotes colon adenocarcinoma progression(2024/05/27)
作者：Yuanbo Cui, Pengju Lv, Chunyan Zhang
期刊：JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY
影響因子 ：3.600
引用產(chǎn)品：CL-0098
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Huaier Regulates Oxaliplatin Resistance in Colorectal Cancer by Regulating Autophagy and Inhibiting the Wnt/β-catenin Signalling Pathway(2024/01/17)
作者：Qi Feng, Mingyi Huo, Xiaoli Yan
期刊：Frontiers in Bioscience-Landmark
影響因子 ：3.100
引用產(chǎn)品：CL-0098
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Thalidomide suppresses migration and invasion of colorectal cancer cells by inhibiting HOXB7-mediated activation of the Wnt/β-catenin signaling pathway(2024/01/05)
作者：Liyang Liu, Wusong Xue
期刊：Chemical Biology & Drug Design
影響因子 ：3.000
引用產(chǎn)品：CL-0098
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