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JEG-3 (人絨毛膜癌細(xì)胞) (STR鑒定正確)
貨號(hào):CL-0127
規(guī)格:1×10?cells/T25培養(yǎng)瓶
價(jià)格: ¥1500
生長(zhǎng)培養(yǎng)基:MEM(含NEAA)+10% FBS+1% P/S
產(chǎn)品概述
名稱 | JEG-3 (人絨毛膜癌細(xì)胞) (STR鑒定正確) |
別稱 | Jeg-3; JEG3; Jeg3; jeg3 |
種屬 | 人 |
生長(zhǎng)特性 | 貼壁細(xì)胞 |
細(xì)胞形態(tài) | 上皮細(xì)胞樣 |
凍存條件 | 凍存液:55% 基礎(chǔ)培養(yǎng)基+40%FBS+5%DMSO 溫度:液氮 |
培養(yǎng)方案A(默認(rèn)) |
生長(zhǎng)培養(yǎng)基:
培養(yǎng)條件:
氣相:空氣,95%;CO2,5%, 溫度:37℃
|
推薦傳代比例 | 1:3-1:4 |
推薦換液頻率 | 2-3次/周 |
背景描述 | JEG-3細(xì)胞是一株超三倍體人類細(xì)胞株。JEG-3細(xì)胞的典型染色體數(shù)為71,發(fā)生率為34%,多倍體率為2.6%。t(4;11)(p15;q13),i(13q),t(10p15q),del(18)(q21)和6個(gè)其他標(biāo)記在大多數(shù)細(xì)胞中常見,另有兩個(gè)標(biāo)記在一些細(xì)胞中可見,在一個(gè)N14和兩個(gè)N22中可見大衛(wèi)星。N2、N5和N9有4個(gè)拷貝,而N7、N13、N18、N21和X為單拷貝,Q-帶檢測(cè)法可以檢測(cè)到單個(gè)Y染色體。 |
年齡(性別) | 男性;胎兒 |
組織來(lái)源 | 胎盤病變;絨毛膜癌 |
細(xì)胞類型 | 腫瘤細(xì)胞 |
腫瘤類型 | 其它腫瘤細(xì)胞 |
生物安全等級(jí) | BSL-1 |
倍增時(shí)間 | ~24-36 hours |
致瘤性 | Yes, in nude mice; forms malignant tumor consistent with choriocarcinoma. |
基因表達(dá)情況 | human chorionic gonadotropin (hCG), human chorionic somatomammotropin (placental lactogen); progesterone |
保藏機(jī)構(gòu) | ATCC; HTB-36 BCRC; 60428 BCRJ; 0123 DSMZ; ACC-463 ECACC; 92120308 |
STR鑒定
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STR位點(diǎn)信息
Amelogenin X,Y CSF1PO 11,12 D2S1338 24 D3S1358 15,16 D5S818 10,11 D7S820 10,12 D8S1179 12 D13S317 9,11 D16S539 13,14 D18S51 14 D19S433 13,15 D21S11 30 FGA 23,24 PentaD 9,12 PentaE 8,12 TH01 9,9.3 TPOX 8 vWA 16 D6S1043 11 D12S391 17,24 D2S441 14,15 -
STR鑒定圖
參考文獻(xiàn)
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Trophoblast-derived miR-410-5p induces M2 macrophage polarization and mediates immunotolerance at the fetal-maternal interface by targeting the STAT1 signaling pathway(2024/01/04)
作者:Jing Yang, Longfei Li, Linlin Wang
期刊:Journal of Translational Medicine
DOI:10.1186/s12967-023-04831-y
影響因子 :7.400
引用產(chǎn)品:CL-0127
-
Talin1 regulates endometrial adhesive capacity through the Ras signaling pathway(2021/03/09)
作者:Saiqiong Chen?,?Bo Liu?,?Jingjing Li?
期刊:Life Sciences
影響因子 :6.780
-
Hsa_circ_0001326 inhibited the proliferation, migration, and invasion of trophoblast cells via miR-145-5p/TGFB2 axis(2023/01/20)
作者:Meiyu Song, Peng Xu, Li Wang
期刊:AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY
影響因子 :3.600
-
IGF2BP3 participates in the pathogenesis of recurrent spontaneous abortion by regulating ferroptosis(2024/05/30)
作者:Fangfang Dai, Yuwei Zhang, Jie Zhang
期刊:JOURNAL OF REPRODUCTIVE IMMUNOLOGY
影響因子 :3.400
引用產(chǎn)品:CL-0127
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Evaluation of transport mechanisms of methotrexate in human choriocarcinoma cell lines by LC-MS/MS(2024/05/29)
作者:Mengru Bai, Qian Shen, Yong Wu
期刊:JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
DOI:10.1016/j.jpba.2024.116268
影響因子 :3.400
引用產(chǎn)品:CL-0127
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IL?1β?induced pentraxin 3 inhibits the proliferation, invasion and cell cycle of trophoblasts in preeclampsia and is suppressed by IL?1β antagonists(2022/02/07)
作者:Xiaoxi Wang, Jing Zhang, Jing Ji
期刊:Molecular Medicine Reports
影響因子 :3.400
引用產(chǎn)品:CL-0127
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The Possible Involvement of miR-371a-5p Regulating XIAP in the Pathogenesis of Recurrent Pregnancy Loss:(2019/2/28)
作者:Erqiu Du, Yuming Cao, Chun Feng
期刊:Reproductive Sciences
影響因子 :2.900
引用產(chǎn)品:CL-0127
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Upregulation of SEMP1 Contributes to Improving the Biological Functions of Trophoblast via the PI3K/AKT Pathway in Preeclampsia(2023/06/05)
作者:Ruijing Chang, Yuan Su, Hongfang Kong
期刊:MOLECULAR BIOTECHNOLOGY
DOI:10.1007/s12033-023-00774-3
影響因子 :2.600
引用產(chǎn)品:CL-0127
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miR-214-5p suppresses the proliferation, migration and invasion of trophoblast cells in pre-eclampsia by targeting jagged 1 to inhibit notch signaling pathway(2020/2/26)
作者:Fengyan Gong, Wei Chai, Junwei Wang
期刊:Acta Histochemica
DOI:10.1016/j.acthis.2020.151527
影響因子 :2.500
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