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DU 145 (人前列腺癌細胞) (STR鑒定正確)
貨號：CL-0075
規(guī)格：1×10?cells/T25培養(yǎng)瓶
價格： ￥1400
生長培養(yǎng)基：MEM（含NEAA）＋10% FBS＋1% P/S
產(chǎn)品概述
| 名稱 | DU 145 (人前列腺癌細胞) (STR鑒定正確) |
| 別稱 | DU-145; Du-145; DU 145; DU_145; Duke University 145 |
| 種屬 | 人 |
| 生長特性 | 貼壁細胞 |
| 細胞形態(tài) | 上皮細胞樣 |
| 凍存條件 | 凍存液：55% 基礎(chǔ)培養(yǎng)基+40%FBS+5%DMSO 溫度：液氮 |
| 培養(yǎng)方案A（默認） |
生長培養(yǎng)基:
培養(yǎng)條件:
氣相：空氣，95%；CO2，5%, 溫度：37℃
|
| 推薦傳代比例 | 1:3-1:4 |
| 推薦換液頻率 | 2-3次/周 |
| 背景描述 | DU 145細胞是從一位有3年淋巴細胞白血病史的前列腺癌患者的腦部轉(zhuǎn)移病灶損害中建株的。DU 145細胞和從軟瓊脂中分離到的細胞不具有可檢測的激素敏感性，酸性磷酸酶呈弱陽性。對DU 145細胞及原始腫瘤細胞的亞顯微結(jié)構(gòu)分析可見微絨毛，微絲及細胞橋粒，有許多線粒體，發(fā)育良好高爾基體和異質(zhì)溶酶體。DU 145細胞不表達前列腺抗體。 |
| 年齡（性別） | 男性；69歲 |
| 組織來源 | 前列腺；轉(zhuǎn)移灶；腦癌 |
| 細胞類型 | 腫瘤細胞 |
| 腫瘤類型 | 前列腺癌細胞 |
| 生物安全等級 | BSL-1 |
| 倍增時間 | ~30-40 hours |
| 致瘤性 | Yes, in nude mice; forms adenocarcinoma (grade II) consistent with prostatic primary. |
| 抗原表達情況 | Blood Type O; Rh+ |
| 保藏機構(gòu) | ATCC; HTB-81 BCRC; 60348 BCRJ; 0078 DSMZ; ACC-261 |
STR鑒定
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STR位點信息
Amelogenin X,Y CSF1PO 10,11 D2S1338 16,17 D3S1358 16 D5S818 10,13 D7S820 7,10,11 D8S1179 13,14 D13S317 12,14 D16S539 11,13 D18S51 12 D19S433 13 D21S11 30,33 FGA 21,22 PentaD 9,13 PentaE 12,14 TH01 7 TPOX 11 vWA 17,18,19 D6S1043 11 D12S391 17,18,20,21 D2S441 9,14 -
STR鑒定圖
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參考文獻
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Retinoblastoma-associated protein is important for TRIM24-mediated activation of the mTOR signaling pathway through DUSP2 action in prostate cancer(2024/03/21)
作者：Da Ren, Wei Li, Ruijiang Zeng
期刊：CELL DEATH AND DIFFERENTIATION
DOI：10.1038/s41418-024-01282-w
影響因子 ：12.400
引用產(chǎn)品：CL-0075
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ND630 controls ACACA and lipid reprogramming in prostate cancer by regulating the expression of circKIF18B_003(2023/12/04)
作者：Yupeng Wu, Wencai Zheng, Qi Huang
期刊：Journal of Translational Medicine
DOI：10.1186/s12967-023-04760-w
影響因子 ：7.400
引用產(chǎn)品：CL-0075
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Metabolic characterization of sphere-derived prostate cancer stem cells reveals aberrant urea cycle in stemness maintenance(2024/04/22)
作者：Yuanyuan Luo, Jiachuan Yu, Zhikun Lin
期刊：INTERNATIONAL JOURNAL OF CANCER
影響因子 ：6.400
引用產(chǎn)品：CL-0075
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A Liquid–Liquid Phase Separation-Related Index Associate with Biochemical Recurrence and Tumor Immune Environment of Prostate Cancer Patients(2023/03/14)
作者：Qi You, Jiayin Chen, Xiaohui Wu
期刊：INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
影響因子 ：5.600
-
Ferredoxin 1 is a cuproptosis-key gene responsible for tumor immunity and drug sensitivity: A pan-cancer analysis.(2022/09/21)
作者：Longfei Yang, Yuwei Zhang, Yang Wang
期刊：Frontiers in Pharmacology
影響因子 ：5.600
引用產(chǎn)品：CL-0002 CL-0010 CL-0052 CL-0075 CL-0109 CL-0185 CL-0222 CL-0227 CM-H019 PM150110 PM150210 PM150910
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Cytotoxic and Antibacterial Meroterpenoids Isolated from the Marine-Derived Fungus Talaromyces sp. M27416(2024/04/20)
作者：Lingzhi Tang, Jinmei Xia, Zhongwei Chen
期刊：Marine Drugs
影響因子 ：5.400
引用產(chǎn)品：CL-0075
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LOC100996425 acts as a promoter in prostate cancer by mediating hepatocyte nuclear factor 4A and the AMPK/mTOR pathway(2021/08/19)
作者：Xiuyan Wang, Bin Song, Mingcui Zang
期刊：Journal Of Cellular And Molecular Medicine
影響因子 ：5.300
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MET inhibition enhances PARP inhibitor efficacy in castration-resistant prostate cancer by suppressing the ATM/ATR and PI3K/AKT pathways(2021/11/10)
作者：Sihai Zhou,?Zhihong Dai,?Liang Wang
期刊：Journal Of Cellular And Molecular Medicine
影響因子 ：5.295
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PCMT1 regulates the migration, invasion, and apoptosis of prostate cancer through modulating the PI3K/AKT/GSK-3β pathway.(2023/10/27)
作者：Jiacheng Zhong, Chao Yuan, Lin Liu
期刊：Aging-US
影響因子 ：5.200
引用產(chǎn)品：CL-0075
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Effect of transmembrane protein 100 on prostate cancer progression by regulating SCNN1D through the FAK/PI3K/AKT pathway(2022/11/11)
作者：Zehua Ye, Yuqi Xia, Lei Li
期刊：Translational Oncology
DOI：10.1016/j.tranon.2022.101578
影響因子 ：4.803
引用產(chǎn)品：CL-0075
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YTHDF2 protein stabilization by the deubiquitinase OTUB1 promotes prostate cancer cell proliferation via PRSS8 mRNA degradation(2024/03/09)
作者：Xuefeng Zhao, Suli Lv, Neng Li
期刊：JOURNAL OF BIOLOGICAL CHEMISTRY
影響因子 ：4.800
引用產(chǎn)品：CL-0075
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Comprehensiveness cuproptosis related genes study for prognosis and medication sensitiveness across cancers, and validation in prostate cancer(2024/04/26)
作者：Longfei Yang, Yifan Tang, Yuwei Zhang
期刊：Scientific Reports
DOI：10.1038/s41598-024-57303-8
影響因子 ：4.600
引用產(chǎn)品：CL-0075
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A pan-cancer analysis of DDR1 in prognostic signature and tumor immunity, drug resistance(2023/04/08)
作者：Longfei Yang, Yuwei Zhang, Yifan Tang
期刊：Scientific Reports
DOI：10.1038/s41598-023-27975-9
影響因子 ：4.600
引用產(chǎn)品：CL-0002 CL-0010 CL-0052 CL-0075 CL-0109 CL-0185 CL-0222 CL-0227 CM-H019 PM150110 PM150210 PM150910
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USF1-mediated ALKBH5 stabilizes FLII mRNA in an m6A-YTHDF2-dependent manner to repress glycolytic activity in prostate adenocarcinoma(2023/07/26)
作者：Dewang Fu, Qingyue Si, Chenxi Yu
期刊：MOLECULAR CARCINOGENESIS
DOI：10.1002/mc.23609
影響因子 ：4.600
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YAP1 inhibits RSL3-induced castration-resistant prostate cancer cell ferroptosis by driving glutamine uptake and metabolism to GSH(2023/09/29)
作者：Xian Fu, Hongshen Wu, Changjiu Li
期刊：MOLECULAR AND CELLULAR BIOCHEMISTRY
DOI：10.1007/s11010-023-04847-4
影響因子 ：4.300
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Meta-biosensor with High Q-factor Based on Wet Etching for Terahertz Detection(2024/02/27)
作者：Xueer Chen, Longfang Ye, Daquan Yu
期刊：IEEE SENSORS JOURNAL
影響因子 ：4.300
引用產(chǎn)品：CL-0075
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Epigenetic-related Gene-based Prognostic Model Construction and Validation in Prostate Adenocarcinoma(2024/05/08)
作者：Youyou Li, Chao Li, Longxiang Wu
期刊：Heliyon
DOI：10.1016/j.heliyon.2024.e30941
影響因子 ：4.000
引用產(chǎn)品：CL-0075
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PLA inhibits TNF-α-induced PANoptosis of prostate cancer cells through metabolic reprogramming(2024/02/24)
作者：Yinghui Hao, Fangmei Xie, Jieyi He
期刊：INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
DOI：10.1016/j.biocel.2024.106554
影響因子 ：4.000
引用產(chǎn)品：CL-0075
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Identification of evodiamine as a suppressor of prostate cancer progression by reducing AR transcriptional activity via targeting Src(2021/10/28)
作者：Pei Cheng,?Xiaofan Zhang,?Xiaofu Wang
期刊：Endocrine
DOI：10.1007/s12020-021-02907-7
影響因子 ：3.925
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Analyzing roles of small nucleolar RNA host gene 25 from clinical, molecular target and tumor formation in prostate cancer(2023/06/10)
作者：Zelin Liu, Shuai Ke, Qinghua Wang
期刊：EXPERIMENTAL CELL RESEARCH
DOI：10.1016/j.yexcr.2023.113686
影響因子 ：3.700
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A cuproptosis-related LncRNA signature: Integrated analysis associated with biochemical recurrence and immune landscape in prostate cancer(2023/02/24)
作者：Lei Ren, Xu Yang, Weifeng Wang
期刊：Frontiers in Genetics
DOI：10.3389/fgene.2023.1096783
影響因子 ：3.700
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Crafting a Personalized Prognostic Model for Malignant Prostate Cancer Patients Using Risk Gene Signatures Discovered through TCGA-PRAD Mining, Machine Learning, and Single-Cell RNA-Sequencing(2023/06/07)
作者：Feng Lyu, Xianshu Gao, Mingwei Ma
期刊：Diagnostics
DOI：10.3390/diagnostics13121997
影響因子 ：3.600
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A Prognostic Model for Prostate Cancer Patients Based on Two DNA Damage Response Mutation-Related Immune Genes(2023/08/22)
作者：Jian Wang, Li Jiang, Zhenhua Shang
期刊：CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS
影響因子 ：3.400
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PEI, a new transfection method, augments the inhibitory effect of RBM5 on prostate cancer(2024/02/21)
作者：Xijia Zhou, Yingshu Cao, Ranwei Li
期刊：BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
DOI：10.1016/j.bbrc.2024.149703
影響因子 ：3.100
引用產(chǎn)品：CL-0075
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Silencing of lncRNA MALAT1 inhibits cell cycle progression via androgen receptor signaling in prostate cancer cells(2019/1/7)
作者：Xiaofan Dai, Lingyun Liu, Zuowen Liang
期刊：Pathology Research And Practice
影響因子 ：2.800
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GPX2 predicts recurrence-free survival and triggers the Wnt/β-catenin/EMT pathway in prostate cancer(2022/10/25)
作者：Ming Yang, Xudong Zhu, Yang Shen
期刊：PeerJ
影響因子 ：2.700
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Exploring the role of differentially expressed metabolic genes and their mechanisms in bone metastatic prostate cancer(2023/04/12)
作者：Qingfu Zhang, Peng Zhang, Zhongting Zhao
期刊：PeerJ
影響因子 ：2.700
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Circ_0044516 Enriches the Level of SARM1 as a miR-330-5p Sponge to Regulate Cell Malignant Behaviors and Tumorigenesis of Prostate Cancer(2022/01/07)
作者：Yan Wu
期刊：Biochemical Genetics
DOI：10.1007/s10528-021-10160-w
影響因子 ：2.400
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TRPM2-L Participates in the Interleukin-6 Pathway to Enhance Tumor Growth in Prostate Cancer by Hypoxia-Inducible Factor-1α(2023/11/10)
作者：Kai Cheng, Qingmei Jia, Christopher Batbatan
期刊：JOURNAL OF INTERFERON AND CYTOKINE RESEARCH
影響因子 ：2.300
引用產(chǎn)品：CL-0075
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Hispidulin inhibits proliferation, migration, and invasion by promoting autophagy via regulation of PPARγ activation in prostate cancer cells and xenograft models(2020/12/15)
作者：Yuanyuan Wang, Shanqi Guo, Yingjie Jia
期刊：Bioscience Biotechnology and Biochemistry
影響因子 ：1.600
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Inhibitory function of CDK12i combined with WEE1i on castration-resistant prostate cancer cells in?vitro and in?vivo(2023/08/08)
作者：Zheng Qin, Dongze Liu, Yueyao Zhang
期刊：Oncologie
DOI：10.1515/oncologie-2023-0233
影響因子 ：0.900
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