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產(chǎn)品概述
Ham's F-12K培養(yǎng)基是Ham's F-12營養(yǎng)混合物的Kaighn's改進(jìn)型，在Ham's F-12的基礎(chǔ)上提高了氨基酸和丙酮酸的濃度，降低了葡萄糖的用量，并修改了鹽的成分和含量（Konigsbergs）。Ham's F-12K培養(yǎng)基最初設(shè)計(jì)用于培養(yǎng)原代人肝細(xì)胞以及分化的大鼠和雞的細(xì)胞。
本產(chǎn)品含有多類細(xì)胞培養(yǎng)所需的氨基酸、維生素、無機(jī)鹽等多種成分，但不含蛋白質(zhì)、脂類或任何生長因子，故此產(chǎn)品需搭配血清或無血清添加物使用。
成分說明
形態(tài) | 液體 |
濃度 | 1× |
規(guī)格 | 500mL |
PH | 7.2～7.4 |
L-谷氨酰胺 | 2mM |
NaHCO3 | 2500mg/L |
D-葡萄糖 | 1260mg/L |
HEPES緩沖劑 | 無 |
酚紅指示劑 | 3mg/L |
儲存條件 | 2～8℃，避光 |
運(yùn)輸條件 | 常溫 |
有效期 | 18個(gè)月 |
注意事項(xiàng)
1、本產(chǎn)品經(jīng)過濾除菌，使用時(shí)應(yīng)注意無菌操作，避免污染；
2、為保持本產(chǎn)品的最佳使用效果，請勿進(jìn)行凍融處理；
3、本產(chǎn)品僅用于科研或進(jìn)一步研究使用，不用于診斷和治療。
參考文獻(xiàn)
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Antioxidant Effects of Roasted Licorice in a Zebrafish Model and Its Mechanisms(2022/11/10)
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Downregulation of circ-RAPGEF5 inhibits colorectal cancer progression by reducing the expression of polypeptide N-acetylgalactosaminyltransferase 3 (GALNT3)(2024/05/22)
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Emodin Protects Against Acute Pancreatitis-Associated Lung Injury by Inhibiting NLPR3 Inflammasome Activation via Nrf2/HO-1 Signaling(2022/10/31)
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Hsa-miR-425-5p promotes tumor growth and metastasis by activating the CTNND1-mediated β-catenin pathway and EMT in colorectal cancer(2020/06/28)
作者：Dingsheng Liu, Hong Zhang, Mingming Cui
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DOI：10.1080/15384101.2020.1783058
影響因子 ：4.300
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Tanshinone IIA (TSIIA) represses the progression of non-small cell lung cancer by the circ_0020123/miR-1299/HMGB3 pathway(2022/12/31)
作者：Fei Sun, Xiaoli Yang, Wei Song
期刊：MOLECULAR AND CELLULAR BIOCHEMISTRY
DOI：10.1007/s11010-022-04646-3
影響因子 ：4.300
引用產(chǎn)品：164210 164210-50 CL-0016 CL-0167 PB180120 PM150110 PM150910
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YAP1 inhibits RSL3-induced castration-resistant prostate cancer cell ferroptosis by driving glutamine uptake and metabolism to GSH(2023/09/29)
作者：Xian Fu, Hongshen Wu, Changjiu Li
期刊：MOLECULAR AND CELLULAR BIOCHEMISTRY
DOI：10.1007/s11010-023-04847-4
影響因子 ：4.300
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Regulation of tumorigenesis and ferroptosis in non-small cell lung cancer by a novel BBOX1-AS1/miR-326/PROM2 axis(2023/08/28)
作者：Jinlu An, Jiang Shi, Chao Yang
期刊：MOLECULAR AND CELLULAR BIOCHEMISTRY
DOI：10.1007/s11010-023-04837-6
影響因子 ：4.300
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CircRNA OXCT1 promotes the malignant progression and glutamine metabolism of non-small cell lung cancer by absorbing miR-516b-5p and upregulating SLC1A5(2023/03/02)
作者：Hua Luo, Jianming Peng, Yuexi Yuan
期刊：CELL CYCLE
DOI：10.1080/15384101.2022.2071565
影響因子 ：4.300
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Circ_0025039 acts an oncogenic role in the progression of non-small cell lung cancer through miR-636-dependent regulation of CORO1C(2022/01/16)
作者：Lei Wang, Cimei Zeng, Zhongren Chen
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DOI：10.1007/s11010-021-04320-0
影響因子 ：4.300
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SPOCK2 and SPRED1 function downstream of EZH2 to impede the malignant progression of lung adenocarcinoma in vitro and in vivo(2023/01/11)
作者：Yang Liu, Xiaoxi Fan, Changrui Jiang
期刊：Human Cell
DOI：10.1007/s13577-023-00855-0
影響因子 ：4.300
-
Network pharmacology?based investigation of potential targets of triptonodiol acting on non-small-cell lung cancer(2023/11/28)
作者：Feng Jin, Xiaochen Ni, Shilong Yu
期刊：EUROPEAN JOURNAL OF MEDICAL RESEARCH
DOI：10.1186/s40001-023-01453-4
影響因子 ：4.200
引用產(chǎn)品：PM150910
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MiR-377-3p inhibits atherosclerosis-associated vascular smooth muscle cell proliferation and migration via targeting neuropilin2(2020/6/26)
作者：Haijun Wang, Zheng Wei, Hulun Li
期刊：Bioscience Reports
影響因子 ：4.000
引用產(chǎn)品：PM150910
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RAB3D, upregulated by aryl hydrocarbon receptor (AhR), promotes the progression of prostate cancer by activating the PI3K/AKT signaling pathway(2022/09/24)
作者：Jingsong Yu, Haipeng Qi, Zheng Wang
期刊：CELL BIOLOGY INTERNATIONAL
影響因子 ：3.900
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Methyl-β-cyclodextrin suppresses the monocyte-endothelial adhesion triggered by lipopolysaccharide (LPS) or oxidized low-density lipoprotein (oxLDL)(2021/08/06)
作者：Guo Chen,?Yun Zhou,?Wendiao Zhang
期刊：Pharmaceutical Biology
DOI：10.1080/13880209.2021.1953540
影響因子 ：3.889
引用產(chǎn)品：PM150910
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PUM2 regulates the formation of thoracic aortic dissection through EFEMP1(2023/04/14)
作者：Kangkang Zhi, Renqi Yin, Hongbo Guo
期刊：EXPERIMENTAL CELL RESEARCH
DOI：10.1016/j.yexcr.2023.113602
影響因子 ：3.700
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PCSK9 inhibitor inclisiran for treating atherosclerosis via regulation of endothelial cell pyroptosis(2022/11/01)
作者：Ni Kong, Qin Xu, Wei Cui
期刊：Annals of Translational Medicine
影響因子 ：3.616
引用產(chǎn)品：PM150910
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Circ-SATB2 (hsa_circ_0008928) and miR-150-5p are regulators of TRIM66 in the regulation of NSCLC cell growth and metastasis of NSCLC cells via the ceRNA pathway(2023/12/12)
作者：Liangji Chen, Yuting Zhou, Hongbing Cheng
期刊：JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY
影響因子 ：3.600
引用產(chǎn)品：PM150910
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CircDUS2L (circ_0039908) promotes lung adenocarcinoma progression by upregulating PGAM1 by acting as a miR-590-5p molecular sponge(2023/07/01)
作者：Qing Tian, Ying Guo, Jinfeng Liu
期刊：JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY
影響因子 ：3.600
引用產(chǎn)品：CL-0005 CL-0016 CL-0668 PB180120 PM150110 PM150210 PM150910
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Hispidulin targets PTGS2 to improve cyclophosphamide-induced cystitis by suppressing NLRP3 inflammasome(2024/02/07)
作者：Songlin Liu, Shuhang Li, Yuping Dong
期刊：NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
DOI：10.1007/s00210-024-02987-y
影響因子 ：3.600
引用產(chǎn)品：PM150910
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Cytoprotective effects of C1s enzyme in macrophages in atherosclerosis mediated through the LRP5 and Wnt/β-catenin pathway(2024/01/12)
作者：Dong Yuan, Zhipeng Zheng, Cheng Shen
期刊：MOLECULAR IMMUNOLOGY
DOI：10.1016/j.molimm.2024.01.002
影響因子 ：3.600
引用產(chǎn)品：PM150910
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P2X7 receptor promotes migration and invasion of non-small cell lung cancer A549 cells through the PI3K/Akt pathways(2023/03/01)
作者：Xue Bai, Qianqian Li, Xiaoxiang Peng
期刊：Purinergic Signalling
DOI：10.1007/s11302-023-09928-z
影響因子 ：3.500
引用產(chǎn)品：PM150910
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Targeting CAMK2N1/CAMK2 inhibits invasion, migration and angiogenesis of non-small cell lung cancer by promoting autophagy and apoptosis via AKT/mTOR signaling pathway(2024/03/14)
作者：Qiang Wang, Chao Zhang, Hai Jiang
期刊：GENE
DOI：10.1016/j.gene.2024.148375
影響因子 ：3.500
引用產(chǎn)品：PM150910
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Methylophiopogonanone?B of Radix Ophiopogonis protects cells from H2O2?induced apoptosis through the NADPH oxidase pathway in HUVECs(2019/8/29)
作者：Liling Wang, Yifeng Zhou, Yuchuan Qin
期刊：Molecular Medicine Reports
影響因子 ：3.400
-
Rosuvastatin protects against oxidized low?density lipoprotein?induced endothelial cell injury of atherosclerosis in?vitro(2018/11/19)
作者：Jianan Geng, Huali Xu, Xiaofeng Yu
期刊：Molecular Medicine Reports
影響因子 ：3.400
-
MiR-214-3p overexpression-triggered chondroitin polymerizing factor (CHPF) inhibition modulates the ferroptosis and metabolism in colon cancer(2024/01/08)
作者：Zhiyuan Yun, Di Wu, Xin Wang
期刊：KAOHSIUNG JOURNAL OF MEDICAL SCIENCES
影響因子 ：3.300
引用產(chǎn)品：PM150910
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IL-17A Promotes the Migration, Invasion and the EMT Process of Lung Cancer Accompanied by NLRP3 Activation(2022/10/30)
作者：Wenping Liu, Miaomiao Xin, Qing Li
期刊：Biomed Research International
影響因子 ：3.246
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Circ_0026359 induces HOXA9 to regulate gastric cancer malignant progression through miR-140-3p(2022/08/22)
作者：Shuirong Lu, Jinlai Lu, Lang Liu
期刊：Applied Biological Chemistry
DOI：10.1186/s13765-022-00726-6
影響因子 ：3.200
-
Hsa_circ_0032389 Enhances Proliferation and Migration in PDGF-BB-Induced Human Aortic Vascular Smooth Muscle Cells(2024/02/20)
作者：Haiyun Qian, Shengwei Ma, Qian Zhou
期刊：Cardiovascular Toxicology
DOI：10.1007/s12012-024-09833-w
影響因子 ：3.200
引用產(chǎn)品：PM150910
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pH-sensitive magnetic microcapsules for simultaneously controlled-releasing two drugs(2021/06/21)
作者：Liwen Tang, Ruiting Yang, Haifang Liu
期刊：International Journal of Polymeric Materials and Polymeric Biomaterials
DOI：10.1080/00914037.2021.1937161
影響因子 ：3.200
-
Concomitant drugs-loaded microcapsules of roxithromycin and theophylline with pH-sensitive controlled-releasing properties(2019/04/12)
作者：You Zhou, Bining Qiu, Xueqiong Yin
期刊：International Journal of Polymeric Materials and Polymeric Biomaterials
DOI：10.1080/00914037.2019.1596917
影響因子 ：3.200
-
Thimerosal, a competitive thioredoxin reductase 1 (TrxR1) inhibitor discovered via high-throughput screening(2023/02/07)
作者：Yicheng Ni, Zhongyuan Luo, Yixin Lv
期刊：BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
DOI：10.1016/j.bbrc.2023.02.014
影響因子 ：3.100
-
The New Role of HNF1A-NAS1/miR-214/INHBA Signaling Axis in Colorectal Cancer(2023/11/24)
作者：Xuan Zhang, Tao Wu, Rujia Qin
期刊：Frontiers in Bioscience-Landmark
影響因子 ：3.100
引用產(chǎn)品：PM150910
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Evaluation of hsa_circ_0000018/let-7f-5p/ FAM96A axis in lung adenocarcinoma progression(2023/11/23)
作者：Qi Li, Min Zhao, Dandan Hu
期刊：Cancer Biomarkers
影響因子 ：3.100
引用產(chǎn)品：PM150910
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Synthesis and evaluation of a 68Ga-labeled spermine derivative for tumor PET imaging(2024/04/26)
作者：Kaixin Qin, Dongmei Shi, Yuzhou Zheng
期刊：NUCLEAR MEDICINE AND BIOLOGY
DOI：10.1016/j.nucmedbio.2024.108915
影響因子 ：3.100
引用產(chǎn)品：PM150910
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Astragaloside IV regulates circ_0001615 and miR-873-5p/LASP1 axis to suppress colorectal cancer cell progression(2024/01/04)
作者：Pengfei Kong, Xuemei Tang, Fang Liu
期刊：Chemical Biology & Drug Design
影響因子 ：3.000
引用產(chǎn)品：PM150910
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Fatty acid metabolism-related molecular subtypes and a novel model for predicting prognosis in bladder cancer patients(2024/01/05)
作者：Wenting Su, Jiayin Chen, Jiangbo Sun
期刊：JOURNAL OF BIOSCIENCES
DOI：10.1007/s12038-023-00383-x
影響因子 ：2.900
引用產(chǎn)品：PM150910
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Expression pattern, tumor immune landscape, and prognostic value of N7?methylguanosine regulators in bladder urothelial carcinoma(2023/03/10)
作者：Chi Zhang, Jiangnan Xia, Simiao Zhang
期刊：Oncology Letters
影響因子 ：2.900
引用產(chǎn)品：PM150910
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CircRNA PRH1-PRR4 stimulates RAB3D to regulate the malignant progression of NSCLC by sponging miR-877-5p(2022/01/25)
作者：Jun Ma, Quanxing Li, Yuling Li
期刊：Thoracic Cancer
影響因子 ：2.900
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Modulation of Vascular Smooth Muscle Cell Multiplication, Apoptosis, and Inflammatory Damage by miR-21 in Coronary Heart Disease(2021/11/27)
作者：Wei Liu, Yilin Li, Dongming Zhao
期刊：Computational and Mathematical Methods in Medicine
影響因子 ：2.809
引用產(chǎn)品：PM150910
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Metformin attenuates TGF-β1-induced pulmonary fibrosis through inhibition of transglutaminase 2 and subsequent TGF-β pathways(2020/06/03)
作者：Yubo Wang, Caiyu Lin, Rui Han
期刊：3 BIOTECH
DOI：10.1007/s13205-020-02278-2
影響因子 ：2.800
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Silencing of lncRNA MALAT1 inhibits cell cycle progression via androgen receptor signaling in prostate cancer cells(2019/1/7)
作者：Xiaofan Dai, Lingyun Liu, Zuowen Liang
期刊：Pathology Research And Practice
影響因子 ：2.800
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Transcription factor E2F3 activates CDC25B to regulate DNA damage and promote mitoxantrone resistance in stomach adenocarcinoma(2024/01/09)
作者：Xiaoming Pan, Chaobo Xu, Guoxiong Cheng
期刊：MOLECULAR BIOLOGY REPORTS
DOI：10.1007/s11033-023-08933-0
影響因子 ：2.800
引用產(chǎn)品：PM150910
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LncRNA RP11-521C20.3 Inhibits Cigarette Smoke Extract-Induced Apoptosis in A549 Cells by Targeting BMF Signaling(2023/04/21)
作者：Yong Zhong, Chuntao Li, Yaling Xiang
期刊：International Journal of Chronic Obstructive Pulmonary Disease
影響因子 ：2.800
引用產(chǎn)品：PM150910
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PKNOX2 suppresses lung cancer cell proliferation by inhibiting the PI3K/AKT/mTOR axis(2023/03/28)
作者：Minglei Song, Nan Zhang, Fumin Cao
期刊：Experimental and Therapeutic Medicine
影響因子 ：2.700
引用產(chǎn)品：PM150910
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Circ_0007422 Knockdown Inhibits Tumor Property and Immune Escape of Colorectal Cancer by Decreasing PDL1 Expression in a miR-1256-Dependent Manner(2024/01/22)
作者：Dian Yin, Li Yang, Xiu Feng
期刊：MOLECULAR BIOTECHNOLOGY
DOI：10.1007/s12033-023-01040-2
影響因子 ：2.600
引用產(chǎn)品：PM150910
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Resveratrol Inhibits Colorectal Cancer Cell Tumor Property by Activating the miR-769-5p/MSI1 Pathway(2024/05/21)
作者：Hongchang Liu, Liangliang Zhang, Liangliang Hao
期刊：MOLECULAR BIOTECHNOLOGY
DOI：10.1007/s12033-024-01167-w
影響因子 ：2.600
引用產(chǎn)品：PM150910
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Exosomal circKDM4A Induces CUL4B to Promote Prostate Cancer Cell Malignancy in a miR-338-3p-Dependent Manner(2022/08/05)
作者：Guangyi Huang, Zeping Jiang, Wuan Zhu
期刊：BIOCHEMICAL GENETICS
DOI：10.1007/s10528-022-10251-2
影響因子 ：2.400
引用產(chǎn)品：PM150910
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Circular RNA Circ_0005962 Contributes to Lung Adenocarcinoma Cell Proliferation and Stem Cell Formation Through Sponging of miR-3611 and Modulating CYP24A1 Expression(2022/12/21)
作者：Wenjing Lu, Zhigao Yu, Jun Liu
期刊：BIOCHEMICAL GENETICS
DOI：10.1007/s10528-022-10312-6
影響因子 ：2.400
引用產(chǎn)品：164210-50 CL-0016 CL-0094 CL-0298 CM-0016 CM-0094 CM-0298 PB180120 PM150110 PM150210 PM150910
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Vitamin B6 ameliorates acute pancreatitis by suppressing the caspase3 signaling pathway(2024/05/02)
作者：Heling Xu, Hongqin Yue, Haijue Ge
期刊：BMC GASTROENTEROLOGY
DOI：10.1186/s12876-024-03248-1
影響因子 ：2.400
引用產(chǎn)品：PM150910
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Depletion of circPDSS1 inhibits ITGA11 production to confer cisplatin sensitivity through miR-515-5p in gastric cancer(2022/12/09)
作者：Yongsen Wang, Shuting Tang, Lingling Li
期刊：JOURNAL OF CHEMOTHERAPY
DOI：10.1080/1120009X.2022.2151702
影響因子 ：2.385
引用產(chǎn)品：PM150910
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Anti-cancer effects of Coix seed extract through KCTD9-mediated ubiquitination of TOP2A in lung adenocarcinoma(2024/02/20)
作者：Jiuyang Jiang, Xue Li, Chun Zhang
期刊：Cell Division
DOI：10.1186/s13008-024-00112-2
影響因子 ：2.300
引用產(chǎn)品：PM150910
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Anlotinib Inhibits Cisplatin Resistance in Non-Small-Cell Lung Cancer Cells by Inhibiting MCL-1 Expression via MET/STAT3/Akt Pathway(2024/03/04)
作者：Lile Wang, Lu Xu, Shuhua Han
期刊：Canadian Respiratory Journal
影響因子 ：2.200
引用產(chǎn)品：PM150910
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Bioactive components and the molecular mechanism of Shengxian Decoction against lung adenocarcinoma based on network pharmacology and molecular docking(2023/12/15)
作者：Ruijiao Yuan, Kejuan Li, Qi Li
期刊：American Journal of Translational Research
DOI：PMID:38186989
影響因子 ：2.200
引用產(chǎn)品：PM150910
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Circular RNA circSDHC (hsa_circ_0015004) regulates tumor growth and angiogenesis via regulating centrosomal protein 55 expression in renal cell carcinoma(2022/10/01)
作者：Long Pei, Chunhui Dong, Yanchao Wang
期刊：HISTOLOGY AND HISTOPATHOLOGY
影響因子 ：2.130
引用產(chǎn)品：PM150910
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Involvement of ZDHHC9 in lung adenocarcinoma: regulation of PD-L1 stability via palmitoylation(2023/03/31)
作者：Zhe Li, Da Jiang, Fengling Liu
期刊：IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL
DOI：10.1007/s11626-023-00755-5
影響因子 ：2.100
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Targeting Thbs1 reduces bladder remodeling caused by partial bladder outlet obstruction via the FGFR3/p-FGFR3 pathway(2023/12/18)
作者：Jun Long, Yafei Yang, Jin Yang
期刊：NEUROUROLOGY AND URODYNAMICS
影響因子 ：2.000
引用產(chǎn)品：PM150910
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Circ_0079530 stimulates THBS2 to promote the malignant progression of non-small cell lung cancer by sponging miR-584-5p(2023/06/01)
作者：Kun Fang, Yibin Deng, Ping Yang
期刊：HISTOLOGY AND HISTOPATHOLOGY
影響因子 ：2.000
引用產(chǎn)品：PM150910
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Higher expression of pseudouridine synthase 7 promotes non-small cell lung cancer progression and suggests a poor prognosis(2023/07/07)
作者：Guihong Zhang, Yongde Zhu, Yonghuang Tan
期刊：Journal of Cardiothoracic Surgery
DOI：10.1186/s13019-023-02332-z
影響因子 ：1.600
引用產(chǎn)品：PM150910
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GATA2/FGF21 Axis Regulates the Effects of High Glucose on the Apoptosis, Autophagy and Oxidative Stress of Human Umbilical Vein Endothelial Cell via PI3K/AKT/mTOR Pathway(2022/03/01)
作者：Jinyan Zheng, Xiaojiang Ma, Yimeng Zhou
期刊：Annals Of Clinical And Laboratory Science
DOI：PMID:35414507
影響因子 ：0.800
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circRNA LDLRAD3 Enhances the Malignant Behaviors of NSCLC Cells via the miR-20a-5p-SLC7A5 Axis Activating the mTORC1 Signaling Pathway(2022/01/06)
作者：Yu Li, Guangle Qin, Jinyun Du
期刊：Journal of Healthcare Engineering
影響因子 ：0.000
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