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產(chǎn)品概述
| 名稱 | NCI-H1975 (人肺腺癌細(xì)胞) (STR鑒定正確) |
| 別稱 | H1975; H-1975 |
| 種屬 | 人 |
| 生長特性 | 貼壁細(xì)胞 |
| 細(xì)胞形態(tài) | 上皮細(xì)胞樣 |
| 凍存條件 | 凍存液：55% 基礎(chǔ)培養(yǎng)基+40%FBS+5%DMSO 溫度：液氮 |
| 培養(yǎng)方案A（默認(rèn)） |
培養(yǎng)條件:
氣相：空氣，95%；CO2，5%, 溫度：37℃
|
| 推薦傳代比例 | 1:3-1:4 |
| 推薦換液頻率 | 2-3次/周 |
| 背景描述 | NCI-H1975細(xì)胞是于1988年7月從一名女性(無抽煙史)非小細(xì)胞肺腺癌組織中分離得到的。 |
| 年齡（性別） | 女性 |
| 組織來源 | 器官：肺；疾?。合侔?；非小細(xì)胞肺癌 |
| 細(xì)胞類型 | 腫瘤細(xì)胞 |
| 腫瘤類型 | 肺癌細(xì)胞 |
| 生物安全等級 | BSL-1 |
| 倍增時間 | ~28-45 hours |
| 保藏機(jī)構(gòu) | ATCC; CRL-5908 |
STR鑒定
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STR位點(diǎn)信息
Amelogenin X CSF1PO 12 D2S1338 17 D3S1358 14,15 D5S818 11,12 D7S820 8,11 D8S1179 13,16 D13S317 10,13 D16S539 9,12 D18S51 13 D19S433 15,15.2 D21S11 28 FGA 21,24 PentaD 12,13 PentaE 12,16 TH01 7 TPOX 8,11 vWA 18 D6S1043 12 D12S391 17 D2S441 10,11 -
STR鑒定圖
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參考文獻(xiàn)
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High-throughput and proteome-wide discovery of endogenous biomolecular condensates(2024/03/18)
作者：Pengjie Li, Peng Chen, Fukang Qi
期刊：Nature Chemistry
DOI：10.1038/s41557-024-01485-1
影響因子 ：21.800
引用產(chǎn)品：CL-0298
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Highly Multiplexed, Efficient, and Automated Single-Cell MicroRNA Sequencing with Digital Microfluidics.(2023/11/28)
作者：Yingwen Chen, Xuanqun Wang, Xing Na
期刊：Small Methods
影響因子 ：12.400
引用產(chǎn)品：CL-0298
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Multivalent DNA Flowers for High-Performance Isolation, Detection, and Release of Tumor-Derived Extracellular Vesicles(2023/11/26)
作者：Yongan Ren, Ke Ge, Wei Lu
期刊：ACS Applied Materials & Interfaces
影響因子 ：9.500
引用產(chǎn)品：CL-0298
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Thioredoxin reductase 1 inhibitor shikonin promotes cell necroptosis via SecTRAPs generation and oxygen-coupled redox cycling(2021/12/30)
作者：Yue Zhang, Shibo Sun, Weiping Xu
期刊：Free Radical Biology And Medicine
DOI：10.1016/j.freeradbiomed.2021.12.314
影響因子 ：8.101
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Targeting TYK2 alleviates Rab27A-induced malignant progression of non-small cell lung cancer via disrupting IFNα-TYK2-STAT-HSPA5 axis(2024/03/23)
作者：Yuanyuan Zeng, Jian Zhao, Zhengyan Wu
期刊：npj Precision Oncology
DOI：10.1038/s41698-024-00574-1
影響因子 ：7.900
引用產(chǎn)品：CL-0298
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LncRNA CCAT2 promotes tumorigenesis by over-expressed Pokemon in non-small cell lung cancer(2017/01/12)
作者：Zhihong Zhao, Ju Wang, Shengfa Wang
期刊：Biomedicine & Pharmacotherapy
DOI：10.1016/j.biopha.2016.12.122
影響因子 ：7.500
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Plumbagin reduction by thioredoxin reductase 1 possesses synergy effects with GLUT1 inhibitor on KEAP1-mutant NSCLC cells(2021/12/23)
作者：Shibo Sun,?Yue Zhang,?Weiping Xu
期刊：Biomedicine & Pharmacotherapy
DOI：10.1016/j.biopha.2021.112546
影響因子 ：7.419
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Design, Synthesis, and Biological Evaluation of Proteolysis-Targeting Chimeras as Highly Selective and Efficient Degraders of Extracellular Signal-Regulated Kinase 5(2023/09/26)
作者：Pengming Pan, Tongtong Geng, Zhongtang Li
期刊：JOURNAL OF MEDICINAL CHEMISTRY
DOI：10.1021/acs.jmedchem.3c00864
影響因子 ：7.300
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Erianin inhibits human lung cancer cell growth via PI3K/Akt/mTOR pathway in vitro and in vivo(2021/03/17)
作者：Huiqiong Zhang, Xiaofang Xie, Gangmin Li
期刊：Phytotherapy Research
DOI：10.1002/ptr.7154
影響因子 ：7.200
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Tumor-suppressive E3 ubiquitin ligase CHIP inhibits the PBK/ERK axis to repress stem cell properties and radioresistance in non-small cell lung cancer(2022/11/27)
作者：Tan, Bo, Zhang, Jingwei, Wang, Wen, Ma, Haibo, Yang, Yuanyuan
期刊：APOPTOSIS
DOI：10.1007/s10495-022-01789-y
影響因子 ：7.200
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Novel 4-anilinoquinazoline derivatives featuring an 1-adamantylmoiety as potent EGFR inhibitors with enhanced activity againstNSCLC cell lines(2016/01/26)
作者：Haiqing Yu, Yanxia Li, Yang Ge
期刊：European Journal of Medicinal Chemistry
DOI：DOI: 10.1016/j.ejmech.2016.01.045
影響因子 ：6.700
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Activation of Hypoxia Inducible Factor-1 Alpha-Mediated DNA Methylation Enzymes (DNMT3a and TET2) Under Hypoxic Conditions Regulates S100A6 Transcription to Promote Lung Cancer Cell Growth and Metastasis(2024/03/18)
作者：Tengfei Wang, Genbao Zhu, Bo Wang
期刊：ANTIOXIDANTS & REDOX SIGNALING
影響因子 ：6.600
引用產(chǎn)品：CL-0298
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Anticancer effect of covalent purine-containing EGFR TKI, ZZC4 and its mechanism of action through network pharmacology(2023/11/27)
作者：Mawusse K.I. Attiogbe, Hongyi Zhao
期刊：LIFE SCIENCES
影響因子 ：6.100
引用產(chǎn)品：CL-0298
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LncRNA CYP4A22-AS1 promotes the progression of lung adenocarcinoma through the miR-205-5p/EREG and miR-34c-5p/BCL-2 axes(2023/09/05)
作者：Liyao Dong, Lin Zhang, Xinyun Zhao
期刊：Cancer Cell International
DOI：10.1186/s12935-023-03036-z
影響因子 ：5.800
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Silencing ZIC2 abrogates tumorigenesis and anoikis resistance of non-small cell lung cancer cells by inhibiting Src/FAK signaling(2021/05/29)
作者：Aibin Liu, Huayan Xie, Ronggang Li
期刊：Molecular Therapy-Oncolytics
DOI：10.1016/j.omto.2021.05.008
影響因子 ：5.700
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Long noncoding RNA FBXL19‐AS1 induces tumor growth and metastasis by sponging miR‐203a‐3p in lung adenocarcinoma(2019/09/20)
作者：Liming Wang, Xin Zhang, Yang Liu
期刊：Journal of Cellular Physiology
影響因子 ：5.600
引用產(chǎn)品：CL-0298
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C1GALT1, Negatively Regulated by miR-181d-5p, Promotes Tumor Progression via Upregulating RAC1 in Lung Adenocarcinoma(2021/070/7)
作者：Xiaoxia Dong, Yongyu Liu, Xinzhou Deng
期刊：Frontiers in Cell and Developmental Biology
影響因子 ：5.500
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Prognostic Value of Genomic Instability of m 6 A-Related lncRNAs in Lung Adenocarcinoma(2022/03/03)
作者：Rui Li, JianPing Li, TingTing Liu
期刊：Frontiers in Cell and Developmental Biology
影響因子 ：5.500
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Inhibition effect of oxyepiberberine isolated from Coptis chinensis franch. On non-small cell lung cancer based on a network pharmacology approach and experimental validation(2021/6/1)
作者：Ying Zhang, Yunfeng Yao, Yingjie Fu
期刊：Journal Of Ethnopharmacology
影響因子 ：5.400
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Structurally Diverse Diterpenes from the South China Sea Soft Coral Sarcophyton trocheliophorum(2023/01/20)
作者：Yuting Song, Dandan Yu, Mingzhi Su
期刊：Marine Drugs
影響因子 ：5.400
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SLCO4A1, as a novel prognostic biomarker of non?small cell lung cancer, promotes cell proliferation and migration(2024/01/23)
作者：Shihao Li, Zihao Li, Lan Huang
期刊：INTERNATIONAL JOURNAL OF ONCOLOGY
影響因子 ：5.200
引用產(chǎn)品：CL-0298
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Exosomal Delivery of FTO Confers Gefitinib Resistance to Recipient Cells through ABCC10 Regulation in an m6A-dependent Manner(2021/02/09)
作者：Peng Xiao, Yukang Liu, Wei Han
期刊：Molecular Cancer Research
DOI：10.1158/1541-7786.MCR-20-0541
影響因子 ：5.200
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Guided Isolation of An Uncommon Cembranoid Orthoester, Sarcotortin A, and Three Skeletal Diverse Terpenoids from the Hainan Soft Coral Sarcophyton tortuosum Based on Molecular Networking Strategy(2022/12/23)
作者：Zihui Chen, Dandan Yu, Cong Li
期刊：CHEMISTRY-A EUROPEAN JOURNAL
影響因子 ：5.020
引用產(chǎn)品：CL-0298
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lncRNA CERS6-AS1 upregulates the expression of ANLN by sponging miR-424-5p to promote the progression and drug resistance of lung adenocarcinoma(2023/12/01)
作者：Zhuo Ting, Zuotao Wu, Chuyi Yang
期刊：Non-coding RNA Research
DOI：10.1016/j.ncrna.2023.11.013
影響因子 ：5.000
引用產(chǎn)品：CL-0298
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GPR37-centered ceRNA network contributes to metastatic potential in lung adenocarcinoma: Evidence from high-throughput sequencing(2023/11/16)
作者：Chuanhui Chen, Mengzhi Wan, Xiong Peng
期刊：Translational Oncology
DOI：10.1016/j.tranon.2023.101819
影響因子 ：5.000
引用產(chǎn)品：CL-0298
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Long non-coding RNA FAM83A antisense RNA 1 (lncRNA FAM83A-AS1) targets microRNA-141-3p to regulate lung adenocarcinoma cell proliferation, migration, invasion, and epithelial-mesenchymal transition progression(2022/02/14)
作者：Hongyu Huang, Chuyi Yang, Qichen Zhang
期刊：Bioengineered
DOI：10.1080/21655979.2022.2037871
影響因子 ：4.900
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GRIN2D knockdown suppresses the progression of lung adenocarcinoma by regulating the E2F signalling pathway(2023/04/19)
作者：Zhitao Chen, Yanhui Song, Peipei Li
期刊：CELLULAR SIGNALLING
DOI：10.1016/j.cellsig.2023.110685
影響因子 ：4.800
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Comprehensive analysis of cuproptosis and copper homeostasis genotyping and related immune land scape in lung adenocarcinoma(2023/10/02)
作者：Dayuan Luo, Xiang Wang, Wei Feng
期刊：Scientific Reports
DOI：10.1038/s41598-023-43795-3
影響因子 ：4.600
引用產(chǎn)品：CL-0298
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IMP4 Silencing Inhibits the Malignancy of Lung Adenocarcinoma via ERK Pathway(2022/10/22)
作者：Ruzhen Li, Zhaohui Han, Wei Ma
期刊：Journal of Oncology
影響因子 ：4.501
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DNA repair/recombination protein 54L promotes the progression of lung adenocarcinoma by activating mTORC1 pathway(2022/12/01)
作者：Changjiang Liu, Wei Ren, Zhixin Zhang
期刊：Human Cell
DOI：10.1007/s13577-022-00832-z
影響因子 ：4.374
引用產(chǎn)品：CL-0298
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LncRNA surfactant associated 1 activates large tumor suppressor kinase 1/Yes-associated protein pathway via modulating hypoxic exosome-delivered miR-4766–5p to inhibit lung adenocarcinoma metastasis(2022/10/22)
作者：Weiqiang Zhang, Miaochun Bai, Keqiang Liu
期刊：INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
DOI：10.1016/j.biocel.2022.106317
影響因子 ：4.000
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Integrated analysis of purine metabolism assists in predicting prognosis and treatment decisions for patients with lung adenocarcinoma(2024/04/04)
作者：Tingting Zhang, Ruhua Chen, Xiangyu Su
期刊：Heliyon
DOI：10.1016/j.heliyon.2024.e29290
影響因子 ：4.000
引用產(chǎn)品：CL-0298
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SLC7A5 is a lung adenocarcinoma-specific prognostic biomarker and participates in forming immunosuppressive tumor microenvironment(2022/10/02)
作者：Yong Liu, Guoyuan Ma, Jichang Liu
期刊：Heliyon
DOI：10.1016/j.heliyon.2022.e10866
影響因子 ：4.000
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Identification of ALG3 as a potential prognostic biomarker in lung adenocarcinoma(2023/07/08)
作者：Yinjiao Yuan, BaoCheng Xie, Dongbo Guo
期刊：Heliyon
DOI：10.1016/j.heliyon.2023.e18065
影響因子 ：4.000
引用產(chǎn)品：CL-0298
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Comprehensive Analysis of a Novel Immune-Related Gene Signature in Lung Adenocarcinoma(2022/10/19)
作者：Hongxiang Feng, Chaoyang Liang, Yuhui Shi
期刊：Journal of Clinical Medicine
影響因子 ：3.900
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Lactate dehydrogenase D serves as a novel biomarker for prognosis and immune infiltration in lung adenocarcinoma(2023/08/16)
作者：Yu Zhang, Tianyi Zhang, Yingdong Zhao
期刊：BMC CANCER
DOI：10.1186/s12885-023-11221-6
影響因子 ：3.800
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TMED3 exerts a protumor function in non-small cell lung cancer by enhancing the Wnt/β-catenin pathway via regulation of AKT(2021/11/7)
作者：Danjie Zhang, Liangzhang Sun, Jin Zhang
期刊：Toxicology And Applied Pharmacology
DOI：10.1016/j.taap.2021.115793
影響因子 ：3.800
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RNA editing enzyme adenosine deaminases acting on RNA 1 deficiency increases the sensitivity of non-small cell lung cancer cells to anlotinib by regulating CX3CR1-fractalkine expression(2021/07/28)
作者：Min Wu, Mengmeng Jin, Xiaohui Cao
期刊：Drug Development Research
影響因子 ：3.800
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Comprehensive analysis of an immune infiltrate-related competitive endogenous RNA network reveals potential prognostic biomarkers for non-small cell lung cancer(2021/12/02)
作者：Caizhi Yang, Leihao Hu, Zhongyu Huang
期刊：PLoS One
DOI：10.1371/journal.pone.0260720
影響因子 ：3.700
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SLC6A8 is involved in the progression of non-small cell lung cancer through the Notch signaling pathway(2020/10/27)
作者：Yan Feng, Xiangyu Guo, Huaping Tang
期刊：Annals of Translational Medicine
影響因子 ：3.616
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Multi-omics analysis of expression profile and prognostic values of connexin family in LUAD(2023/07/17)
作者：Peng Jiang, Xingfa Huo, Bowen Dong
期刊：JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
DOI：10.1007/s00432-023-05075-5
影響因子 ：3.600
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Circ_0006324 regulates cell proliferation, cell-cycle progression, apoptosis, and glycolysis of non-small cell lung cancer cells through miR-496/TRIM59 axis(2023/08/07)
作者：Tao Wang, Xu Zhu, Kai Wang
期刊：JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY
影響因子 ：3.600
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Silencing of circ_0088036 inhibits growth and invasion of lung adenocarcinoma through miR-203/SP1 axis(2024/03/27)
作者：Xiuhua Liu, Yan Feng, Linna Wang
期刊：JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY
影響因子 ：3.600
引用產(chǎn)品：CL-0298
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Intelligent Genetic Decoding System Based on Nucleic Acid Isothermal Amplification for Non-Small Cell Lung Cancer Diagnosis(2023/03/12)
作者：Xiaonan Liu, Jiaxing Zhang, Kai Hua
期刊：Micromachines
影響因子 ：3.400
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Hydrogen Peroxide-Inducible PROTACs for Targeted Protein Degradation in Cancer Cells(2023/07/18)
作者：Dehao Yu, Heli Fan, Zhili Zhou
期刊：CHEMBIOCHEM
影響因子 ：3.200
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METTL3 promotes non-small cell lung cancer (NSCLC) cell proliferation and colony formation in a m6A-YTHDF1 dependent way(2022/08/25)
作者：Xuejun Dou, Zhiyuan Wang, Weiqiang Lu
期刊：BMC Pulmonary Medicine
DOI：10.1186/s12890-022-02119-3
影響因子 ：3.100
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IGF2BP1 enhances the stability of SIK2 mRNA through m6A modification to promote non-small cell lung cancer progression(2023/10/12)
作者：Yan Xu, Li Xu, Yi Kong
期刊：BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
DOI：10.1016/j.bbrc.2023.10.045
影響因子 ：3.100
引用產(chǎn)品：CL-0298
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Mechanisms analysis for Formononetin counteracted-Osimertinib resistance in non-small cell lung cancer cells: From the insight into the gene transcriptional level(2023/12/28)
作者：Runyang Yin, Jing Gao, Yang Liu
期刊：Chemical Biology & Drug Design
影響因子 ：3.000
引用產(chǎn)品：CL-0298
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Budding uninhibited by benzimidazoles 1 overexpression is associated with poor prognosis and malignant phenotype: A promising therapeutic target for lung adenocarcinoma(2023/02/24)
作者：Rui Chen, Zhiping Wang, Tianzhu Lu
期刊：Thoracic Cancer
影響因子 ：2.900
引用產(chǎn)品：CL-0016 CL-0161 CL-0165 CL-0166 CL-0298 CL-0668 CM-0161
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Mechanism of Key Ingredient of Astragalus membranaceus on Lung Adenocarcinoma via PI3K/AKT Signaling Clarified by Utilizing Network Pharmacology Approach and Experimental Validation(2022/08/31)
作者：Yuanchun Wang, Jianrong Hui, Gang Xiao
期刊：Chinese Journal of Integrative Medicine
影響因子 ：2.900
引用產(chǎn)品：CL-0298
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MNX1 facilitates the malignant progress of lung adenocarcinoma through transcriptionally upregulating CCDC34(2023/06/13)
作者：Junhua Wu, Chongmei Yue, Weiguo Xu
期刊：Oncology Letters
影響因子 ：2.900
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Calponin 3 suppresses proliferation, migration and invasion of non?small cell lung cancer cells(2021/7/1)
作者：Chenglin Yang, Shiping Zhu, Weifeng Feng
期刊：Oncology Letters
影響因子 ：2.900
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Anti-tumor cembrane diterpenoids from the South China Sea soft coral Lobophytum sp.(2023/02/28)
作者：Fan Yang, Yuting Song, Dandan Yu
期刊：CHEMISTRY & BIODIVERSITY
影響因子 ：2.900
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Long noncoding RNA LINC00968 inhibits proliferation, migration and invasion of lung adenocarcinoma through targeting miR-22-5p/CDC14A axis(2021/09/14)
作者：Chao Wu, Xuzhao Bian, Liyuan Zhang
期刊：3 BIOTECH
DOI：10.1007/s13205-021-02981-8
影響因子 ：2.893
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Knockdown of lncRNA MIR503HG suppresses proliferation and promotes apoptosis of non-small cell lung cancer cells by regulating miR-489-3p and miR-625-5p(2020/01/10)
作者：Runa Dao, Muli Wudu, Linping Hui
期刊：Pathology Research and Practice
影響因子 ：2.800
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LncRNA PCAT6 promotes proliferation, migration, invasion, and epithelial-mesenchymal transition of lung adenocarcinoma cell by targeting miR-545-3p(2023/02/14)
作者：Chuyi Yang, Hongyu Huang, Yongpeng Li
期刊：MOLECULAR BIOLOGY REPORTS
DOI：10.1007/s11033-023-08259-x
影響因子 ：2.800
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Anticancer roles of let?7f?1?3p in non?small cell lung cancer via direct targeting of integrin β1(2021/9/16)
作者：Yanan Yang, Yuanrong Liu,Ning Xie
期刊：Experimental and Therapeutic Medicine
影響因子 ：2.700
引用產(chǎn)品：CL-0298
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Dysregulated expression of microRNA involved in resistance to osimertinib in EGFR mutant non-small cell lung cancer cells(2023/04/24)
作者：Dianbao Zhang, Yukun Yang, Yixin Kang
期刊：Journal of Thoracic Disease
影響因子 ：2.500
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CircSFMBT2 Plays an Oncogenic Role in Lung Adenocarcinoma Depending on the miR-1305/SALL4 Axis(2023/12/21)
作者：Xuan Zhao, Xiaojing Xing, Yongkai Wu
期刊：BIOCHEMICAL GENETICS
DOI：10.1007/s10528-023-10611-6
影響因子 ：2.400
引用產(chǎn)品：CL-0298
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Circular RNA Circ_0005962 Contributes to Lung Adenocarcinoma Cell Proliferation and Stem Cell Formation Through Sponging of miR-3611 and Modulating CYP24A1 Expression(2022/12/21)
作者：Wenjing Lu, Zhigao Yu, Jun Liu
期刊：BIOCHEMICAL GENETICS
DOI：10.1007/s10528-022-10312-6
影響因子 ：2.400
引用產(chǎn)品：164210-50 CL-0016 CL-0094 CL-0298 CM-0016 CM-0094 CM-0298 PB180120 PM150110 PM150210 PM150910
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Hsa_circ_0080608 Attenuates Lung Cancer Progression by Functioning as a Competitive Endogenous RNA to Regulate the miR-661/ADRA1A Pathway(2023/10/11)
作者：Chengbo Ren, Ling Cui, Ruibiao Li
期刊：HORMONE AND METABOLIC RESEARCH
影響因子 ：2.200
引用產(chǎn)品：CL-0298
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PSMD12 promotes non-small cell lung cancer progression through activating the Nrf2/TrxR1 pathway(2024/01/19)
作者：Junqi Lv, Shengmao Ma, Xiaowen Wang
期刊：Genes & Genomics
DOI：10.1007/s13258-023-01484-5
影響因子 ：2.100
引用產(chǎn)品：CL-0298
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USF1-CHCHD4 axis promotes lung adenocarcinoma progression partially via activating the MYC pathway(2022/12/08)
作者：Yuhui Zhou, Yunxia Zhao, Wei Ma
期刊：Discover Oncology
DOI：10.1007/s12672-022-00600-3
影響因子 ：0.000
引用產(chǎn)品：CL-0298
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