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產(chǎn)品概述
名稱 | Jurkat, Clone E6-1 (人T淋巴細胞白血病細胞) (STR鑒定正確) |
別稱 | JurkatE6-1; Jurkat E6-1; Jurkat, Clone E6-1; Jurkat Clone E6-1; Jurkat (clone E6-1); JURKAT E-6.1; JURKAT E-61; Jurkat-E6; Jurkat E6; J.E6-1; E6-1 |
種屬 | 人 |
生長特性 | 懸浮細胞 |
細胞形態(tài) | 淋巴細胞樣 |
凍存條件 | 凍存液:55% 基礎(chǔ)培養(yǎng)基+40%FBS+5%DMSO 溫度:液氮 |
培養(yǎng)方案A(默認) |
培養(yǎng)條件:
氣相:空氣,95%;CO2,5%, 溫度:37℃
|
推薦傳代比例 | 3×10^5-5×10^5cells/mL |
推薦換液頻率 | 2-3次/周 |
注意事項 | 該細胞為懸浮細胞,請注意離心收集細胞懸液;請勿直接倒掉細胞培養(yǎng)液。 |
背景描述 | Jurkat, Clone E6-1細胞是Jurkat-FHCRC細胞株(Jurkat細胞株的衍生)的一個克隆。Jurkat, Clone E6-1細胞來源于一個14歲男孩的外周血,經(jīng)佛波酯和外源凝集素或抗T3單克隆抗體(兩種類型的誘導都需要)誘導后可產(chǎn)生大量IL-2。 |
年齡(性別) | 男性;14歲 |
組織來源 | T淋巴細胞;急性T細胞白血病 |
細胞類型 | 腫瘤細胞 |
腫瘤類型 | 白血病細胞 |
生物安全等級 | BSL-1 |
倍增時間 | ~24-48 hours |
受體表達情況 | T cell antigen receptor, expressed |
抗原表達情況 | CD3; Homo sapiens, expressed |
基因表達情況 | interleukin-2 (interleukin 2, IL-2), CD3; Homo sapiens, expressed |
保藏機構(gòu) | ATCC; TIB-152 BCRC; 60424 BCRJ; 0125 ECACC; 88042803 |
STR鑒定
-
STR位點信息
Amelogenin X,Y CSF1PO 11,12 D2S1338 19,23 D3S1358 15 D5S818 9 D7S820 8,12 D8S1179 13,14 D13S317 8,12 D16S539 11 D18S51 13,21 D19S433 14,15.2 D21S11 31.2,33.2 FGA 20,21 PentaD 11,13 PentaE 10,12 TH01 6,9.3 TPOX 8,10 vWA 18 D6S1043 11 D12S391 23 D2S441 14,15 -
STR鑒定圖
參考文獻
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Single-cell analysis of peripheral blood from high-altitude pulmonary hypertension patients identifies a distinct monocyte phenotype(2023/03/31)
作者:Xinhua Wu, Yangyang He, Zhangrong Chen
期刊:Nature Communications
DOI:10.1038/s41467-023-37527-4
影響因子 :16.600
-
Suppression of Tumor or Host Intrinsic CMTM6 Drives Antitumor Cytotoxicity in a PD-L1–Independent Manner(2023/02/03)
作者:Yiru Long, Runqiu Chen, Xiaolu Yu
期刊:Cancer Immunology Research
DOI:10.1158/2326-6066.CIR-22-0439
影響因子 :10.100
引用產(chǎn)品:CL-0005 CL-0007 CL-0019 CL-0071 CL-0105 CL-0129 CL-0140 CL-0196 CL-0246 CL-0319
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An IgD-Fc-Ig fusion protein restrains the activation of T and B cells by inhibiting IgD-IgDR-Lck signaling in rheumatoid arthritis(2021/04/16)
作者:Xiaoxi Hu, Aijun Zhang, Wenwen Pan
期刊:Acta Pharmacologica Sinica
DOI:10.1038/s41401-021-00665-w
影響因子 :8.200
引用產(chǎn)品:CL-0129
-
Identification of the regulatory role of lncRNA HCG18 in myasthenia gravis by integrated bioinformatics and experimental analyses(2021/11/18)
作者:Shuang Li, Xu Wang, Tianfeng Wang
期刊:Journal of Translational Medicine
DOI:10.1186/s12967-021-03138-0
影響因子 :7.400
引用產(chǎn)品:CL-0129
-
Expression of HSPA14 in patients with acute HIV-1 infection and its effect on HIV-1 replication(2023/02/09)
作者:Mingyuan Bi, Wen Kang, Yongtao Sun
期刊:Frontiers in Immunology
DOI:10.3389/fimmu.2023.1123600
影響因子 :7.300
-
Therapeutic exosomal vaccine for enhanced cancer immunotherapy by mediating tumor microenvironment( 2021/12/17)
作者:Fangfang Lv, Huifang Liu, Gaoqian Zhao
期刊:iScience
DOI:10.1016/j.isci.2021.103639
影響因子 :5.800
引用產(chǎn)品:CL-0129
-
Upregulation of IL-37 in epithelial cells: A potential new mechanism of T cell inhibition induced by tacrolimus(2023/09/09)
作者:Zhangci Su, Jingyi Lu, Zihang Ling
期刊:BIOCHEMICAL PHARMACOLOGY
影響因子 :5.800
引用產(chǎn)品:CL-0129
-
ASCT2-mediated glutamine uptake promotes Th1 differentiation via ROS-EGR1-PAC1 pathway in oral lichen planus(2023/08/25)
作者:Wei Li, Zihang Ling, Jinmei Wang
期刊:BIOCHEMICAL PHARMACOLOGY
影響因子 :5.800
引用產(chǎn)品:CL-0129
-
ASCT2-mediated glutamine uptake of epithelial cells facilitates CCL5-induced T cell infiltration via ROS-STAT3 pathway in oral lichen planus(2023/04/26)
作者:Jingyi Lu, Zhangci Su, Wei Li
期刊:INTERNATIONAL IMMUNOPHARMACOLOGY
DOI:10.1016/j.intimp.2023.110216
影響因子 :5.600
引用產(chǎn)品:CL-0129
-
Cosmc transfection decreases malignant behavior of Tn+ cells and enhances sensitivity to apoptosis when induced by Apo2L/TRAIL via alteration of O-glycan structure(2021/10/13)
作者:Ruisong Ding, Xingyou Hu, Wen Hu
期刊:Aging-US
影響因子 :5.200
-
CXCL9, 10, 11/CXCR3 Axis Contributes to the Progress of Primary Sjogren’s Syndrome by Activating GRK2 to Promote T Lymphocyte Migration(2023/02/18)
作者:Jing Zhang, Xiao Zhang, Xingjie Shi
期刊:INFLAMMATION
DOI:10.1007/s10753-023-01791-9
影響因子 :5.100
引用產(chǎn)品:CL-0129
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Glyoxalase 1 inhibitor BBGC suppresses the progression of chronic lymphocytic leukemia and promotes the efficacy of Palbociclib(2023/02/02)
作者:Jiameng Tang, Jialing Zhong, Zheng Yang
期刊:BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
DOI:10.1016/j.bbrc.2023.01.034
影響因子 :3.100
引用產(chǎn)品:CL-0129
-
MicroRNA?155?5p affects regulatory T cell activation and immunosuppressive function by targeting BCL10 in myasthenia gravis(2023/11/09)
作者:Jing Sun, Mengjiao Sun, Xiaoling Li
期刊:Experimental and Therapeutic Medicine
影響因子 :2.700
引用產(chǎn)品:CL-0129
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Circ_0000745 regulates NOTCH1-mediated cell proliferation and apoptosis in pediatric T-cell acute lymphoblastic leukemia through adsorbing miR-193b-3p(2021/11/09)
作者:Huanhuan Feng, Fei Li, Ping Tang
期刊:Hematology
DOI:10.1080/16078454.2021.1997197
影響因子 :1.900
引用產(chǎn)品:164210 164210-50 CL-0058 CL-0129 CP-H158 PB180120 PM150110
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