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Hepa 1-6 (小鼠肝癌細(xì)胞) (STR鑒定正確)
貨號(hào)：CL-0105
規(guī)格：1×10?cells/T25培養(yǎng)瓶
價(jià)格： ￥1200
生長(zhǎng)培養(yǎng)基：DMEM（含丙酮酸鈉）＋10% FBS＋1% P/S
產(chǎn)品概述
| 名稱 | Hepa 1-6 (小鼠肝癌細(xì)胞) (STR鑒定正確) |
| 別稱 | HEPA 1-6; Hepa1-6 |
| 種屬 | 小鼠 |
| 生長(zhǎng)特性 | 貼壁細(xì)胞 |
| 細(xì)胞形態(tài) | 上皮細(xì)胞樣 |
| 凍存條件 | 凍存液：55% 基礎(chǔ)培養(yǎng)基+40%FBS+5%DMSO 溫度：液氮 |
| 培養(yǎng)方案A（默認(rèn)） |
生長(zhǎng)培養(yǎng)基:
培養(yǎng)條件:
氣相：空氣，95%；CO2，5%, 溫度：37℃
|
| 推薦傳代比例 | 1:3-1:4 |
| 推薦換液頻率 | 2-3次/周 |
| 背景描述 | Hepa 1-6細(xì)胞是C57/L小鼠中產(chǎn)生的BW7756小鼠肝癌的衍生株。 |
| 年齡（性別） | 雌性 |
| 組織來源 | 肝；肝癌 |
| 細(xì)胞類型 | 腫瘤細(xì)胞 |
| 腫瘤類型 | 肝膽癌細(xì)胞 |
| 生物安全等級(jí) | BSL-1 |
| 倍增時(shí)間 | ~24-30 hours |
| 基因表達(dá)情況 | albumin, alpha fetoprotein (AFP, alpha-fetoprotein); albumin; alpha 1 antitrypsin (alpha-1-antitrypsin); amylase |
| 保藏機(jī)構(gòu) | ATCC; CRL-1830 BCRC; 60051 DSMZ; ACC-175 ECACC; 92110305 |
STR鑒定
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STR位點(diǎn)信息
18-3 16,17 6-7 15 5-5 17 X-1 25 1-2 13 7-1 25.2 8-1 15 1-1 14,15,16 19-2 10,11 15-3 17,18,19 12-1 17 6-4 18,19 4-2 18.3,19.3 3-2 10 2-1 14 13-1 17.2
11-2 16 17-2 14 -
STR鑒定圖
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參考文獻(xiàn)
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Disruption of SIRT7 Increases the Efficacy of Checkpoint Inhibitor via MEF2D Regulation of Programmed Cell Death 1 Ligand 1 in Hepatocellular Carcinoma Cells(2019/10/31)
作者：Junyu Xiang, Ni Zhang, Juan Feng
期刊：Gastroenterology
DOI：10.1053/j.gastro.2019.10.025
影響因子 ：29.400
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Oncolytic adenovirus programmed by synthetic gene circuit for cancer immunotherapy(2019/10/22)
作者：Huiya Huang,Yiqi Liu, Weixi Liao
期刊：Nature Communications
DOI：10.1038/s41467-019-12794-2
影響因子 ：16.600
引用產(chǎn)品：CL-0105
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Suppression of Tumor or Host Intrinsic CMTM6 Drives Antitumor Cytotoxicity in a PD-L1–Independent Manner(2023/02/03)
作者：Yiru Long, Runqiu Chen, Xiaolu Yu
期刊：Cancer Immunology Research
DOI：10.1158/2326-6066.CIR-22-0439
影響因子 ：10.100
引用產(chǎn)品：CL-0005 CL-0007 CL-0019 CL-0071 CL-0105 CL-0129 CL-0140 CL-0196 CL-0246 CL-0319
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The spatial and single-cell analysis reveals remodeled immune microenvironment induced by synthetic oncolytic adenovirus treatment(2023/11/24)
作者：Gan Liu, Qifan Hu, Shuguang Peng
期刊：CANCER LETTERS
DOI：10.1016/j.canlet.2023.216485
影響因子 ：9.700
引用產(chǎn)品：CL-0105
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LncRNA CRNDE Drives the Progression of Hepatocellular Carcinoma by inducing the Immunosuppressive Niche(2024/01/01)
作者：Xianying Li, Shuhang Liang, Mingming Fei
期刊：International Journal of Biological Sciences
影響因子 ：9.200
引用產(chǎn)品：CL-0105
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Systemic Deficiency of GHR in Pigs leads to Hepatic Steatosis via Negative Regulation of AHR Signaling(2021/10/03)
作者：Qi Han, Huiling Chen, Likai Wang
期刊：International Journal of Biological Sciences
影響因子 ：9.200
引用產(chǎn)品：CL-0105
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Mitochondrial respiratory chain dysfunction mediated by ROS is a primary point of fluoride-induced damage in Hepa1-6 cells(2019/10/07)
作者：Hongwei Wang, Yan Zhang, Panpan Tan
期刊：Environmental Pollution
DOI：10.1016/j.envpol.2019.113359
影響因子 ：8.900
引用產(chǎn)品：CL-0105
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Visualization system based on hierarchical targeting for diagnosis and treatment of hepatocellular carcinoma(2022/08/22)
作者：Shasha Shi, Huipu Li, Xi Zheng
期刊：Materials Today Bio
DOI：10.1016/j.mtbio.2022.100398
影響因子 ：8.200
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Improved anti-hepatocellular carcinoma effect by enhanced Co-delivery of Tim-3 siRNA and sorafenib via multiple pH triggered drug-eluting nanoparticles(2022/07/06)
作者：Chenghua Song, Jia Zhang, Ruichao Wen
期刊：Materials Today Bio
DOI：10.1016/j.mtbio.2022.100350
影響因子 ：8.200
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Synergistic Effects of Nanoscale CaO2 Combined with PD-1 Inhibitors in the Treatment of Hepatocellular Carcinoma: A Promising Combination(2023/01/04)
作者：Yingliang Wang, Shuguang Ju, Huimin Zhou
期刊：International Journal of Nanomedicine
影響因子 ：8.000
引用產(chǎn)品：CL-0105
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Sono-Immunotherapy Mediated Controllable Composite Nano Fluorescent Probes Reprogram the Immune Microenvironment of Hepatocellular Carcinoma(2023/10/25)
作者：Yichi Chen, Bolin Wu, Haitao Shang
期刊：International Journal of Nanomedicine
影響因子 ：8.000
引用產(chǎn)品：CL-0105
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NME4 mediates metabolic reprogramming and promotes nonalcoholic fatty liver disease progression(2023/12/14)
作者：Shaofang Xie,Lei Yuan,Yue Sui
期刊：EMBO REPORTS
DOI：10.1038/s44319-023-00012-6
影響因子 ：7.700
引用產(chǎn)品：CL-0105
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Tumor cell density dependent IL-8 secretion induces the fluctuation of tregs/CD8?+?T cells infiltration in hepatocellular carcinoma: one prompt for the existence of density checkpoint(2023/03/17)
作者：Mengchao Yan, Jia Yao, Yan Lin
期刊：Journal of Translational Medicine
DOI：10.1186/s12967-023-04060-3
影響因子 ：7.400
引用產(chǎn)品：CL-0105
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Protein-Gold Nanoclusters Loaded with Ferrous Ions for Inducing Ferroptosis of Hepatoma Cells(2023/04/05)
作者：Chunyan Jiang, Xin Liu, Zhenhua Li
期刊：Advanced Materials Technologies
影響因子 ：6.800
引用產(chǎn)品：CL-0105
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Oncogenic β-catenin-driven liver cancer is susceptible to methotrexate-mediated disruption of nucleotide synthesis(2023/08/23)
作者：Fangming Liu, Yuting Wu, Baohui Zhang
期刊：CHINESE MEDICAL JOURNAL
DOI：10.1097/CM9.0000000000002816
影響因子 ：6.100
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Lack of Mof reduces acute liver injury by enhancing transcriptional activation of Igf1(2021/2/26)
作者：Meng Wang, Haoyu Liu, Xu Zhang
期刊：Journal Of Cellular Physiology
影響因子 ：5.600
引用產(chǎn)品：CL-0105
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Parathyroid hormone alleviates non-alcoholic liver steatosis via activating the hepatic cAMP/PKA/CREB pathway.(2022/08/17)
作者：Xu Feng, Ye Xiao, Qi Guo
期刊：Frontiers in Endocrinology
影響因子 ：5.200
引用產(chǎn)品：CL-0105
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Astaxanthin Augmented the Anti-Hepatocellular Carcinoma Efficacy of Sorafenib Through the Inhibition of the JAK2/STAT3 Signaling Pathway and Mitigation of Hypoxia within the Tumor Microenvironment(2023/12/07)
作者：Pengfei Ren, Qingjuan Tang, Xinjia He
期刊：MOLECULAR NUTRITION & FOOD RESEARCH
影響因子 ：5.200
引用產(chǎn)品：CL-0105
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Multi-omics study on the molecular mechanism of anlotinib in regulating tumor metabolism(2024/05/09)
作者：Yu Lu, Xuedan Han, Hongwei Zhang
期刊：EUROPEAN JOURNAL OF PHARMACOLOGY
DOI：10.1016/j.ejphar.2024.176639
影響因子 ：5.000
引用產(chǎn)品：CL-0105
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Hepatic Symbiotic Bacterium L. reuteri FLRE5K1 Inhibits the Development and Progression of Hepatocellular Carcinoma via Activating the IFN-γ/CXCL10/CXCR3 Pathway(2023/06/08)
作者：Nan Zhang, Shuiwen Ye, Xinlu Wang
期刊：Probiotics and Antimicrobial Proteins
DOI：10.1007/s12602-023-10098-y
影響因子 ：4.900
引用產(chǎn)品：CL-0105
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Insulin-like growth factor binding protein 3 gene of golden pompano (TroIGFBP3) promotes antimicrobial immune defense(2020/04/08)
作者：Yang Chen, Yongcan Zhou, Xiaoyu Yang
期刊：Fish & Shellfish Immunology
影響因子 ：4.700
引用產(chǎn)品：CL-0105
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TroTNFSF6, a tumor necrosis factor ligand superfamily member, promotes antibacterial immune response of golden pompano, Trachinotus ovatus(2022/12/11)
作者：Chunsheng Liu, Lu Wang, Xiaojuan Chen
期刊：Fish & Shellfish Immunology
影響因子 ：4.700
引用產(chǎn)品：CL-0105
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Decoding the complexity of on-target integration: characterizing DNA insertions at the CRISPR-Cas9 targeted locus using nanopore sequencing(2024/02/17)
作者：Juanjuan Zhao, Xinyu Sun, Saining Tian
期刊：BMC GENOMICS
DOI：10.1186/s12864-024-10050-6
影響因子 ：4.400
引用產(chǎn)品：CL-0105
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Microwave ablation combined with anti-PD-1 therapy enhances systemic antitumor immunity in a multitumor murine model of Hepa1-6(2022/02/06)
作者：Songjiang Huang, Tongqiang Li, Yang Chen
期刊：International Journal Of Hyperthermia
DOI：10.1080/02656736.2022.2032406
影響因子 ：3.100
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A Comparative Study of Antitumor Immunity Induced by Radiofrequency Microwave and Cryoablation in Hepatocellular Carcinoma(2023/10/27)
作者：Kai Zhang, Ming liu, Lin Cong
期刊：APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
DOI：10.1007/s12010-023-04760-y
影響因子 ：3.000
引用產(chǎn)品：CL-0105
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產(chǎn)品資料
識(shí)別碼示意圖
![P3/NSI/1-Ag4-1 [NS-1] (小鼠骨髓瘤細(xì)胞) (種屬鑒定正確)](/Public/upfile/pic/xbx/CL-0409-1.jpg)
娜胡文君.png "邱國(guó)娜/胡文君")
.png "梅文強(qiáng)")
