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Saos-2 (人成骨肉瘤細(xì)胞) (STR鑒定正確)
貨號(hào)：CL-0202
規(guī)格：1×10?cells/T25培養(yǎng)瓶
價(jià)格： ￥1600
生長(zhǎng)培養(yǎng)基：McCoy’s 5A＋15% FBS＋1% P/S
產(chǎn)品概述
| 名稱 | Saos-2 (人成骨肉瘤細(xì)胞) (STR鑒定正確) |
| 別稱 | SAOS-2; Saos-2; SAOS 2; Saos 2; Saos2; SaOs2; SAOS2; Sarcoma OSteogenic-2; SaOS; SAOS |
| 種屬 | 人 |
| 生長(zhǎng)特性 | 貼壁細(xì)胞 |
| 細(xì)胞形態(tài) | 上皮細(xì)胞樣 |
| 凍存條件 | 凍存液：55% 基礎(chǔ)培養(yǎng)基+40%FBS+5%DMSO 溫度：液氮 |
| 培養(yǎng)方案A（默認(rèn)） |
生長(zhǎng)培養(yǎng)基:
培養(yǎng)條件:
氣相：空氣，95%；CO2，5%, 溫度：37℃
|
| 推薦傳代比例 | 1:2-1:3 |
| 推薦換液頻率 | 2-3次/周 |
| 背景描述 | Saos-2細(xì)胞是由J·Fogh和G·Trempe分離和鑒定的眾多人腫瘤細(xì)胞系中的一種。該病人曾經(jīng)多種藥物治療，包括RTG、methotrexate、adriamycin vincristine、cytoxan和aramycin-C。Saos-2細(xì)胞在免疫抑制小鼠中不致瘤，但在半固體培養(yǎng)基中形成集落。 |
| 年齡（性別） | 女性；11歲 |
| 組織來源 | 骨；骨肉瘤 |
| 細(xì)胞類型 | 腫瘤細(xì)胞 |
| 腫瘤類型 | 肉瘤細(xì)胞 |
| 生物安全等級(jí) | BSL-1 |
| 倍增時(shí)間 | ~48 hours |
| 致瘤性 | No, The cells were not tumorigenic in immunosuppressed mice, but did form colonies in semisolid medium. |
| 受體表達(dá)情況 | epidermal growth factor (EGF); transforming growth factor beta (Type 1 and Type 2) |
| 抗原表達(dá)情況 | Blood Type B, Rh+; HLA A2, A3, Bw16, Bw47 |
| 保藏機(jī)構(gòu) | ATCC; CRL-7939ATCC; HTB-85 DSMZ; ACC-243 ECACC; 89050205 |
STR鑒定
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STR位點(diǎn)信息
Amelogenin X CSF1PO 10 D2S1338 18 D3S1358 18 D5S818 12 D7S820 8,10 D8S1179 10,12 D13S317 12,13 D16S539 12,13 D18S51 15 D19S433 13 D21S11 28,30 FGA 22,25 PentaD 11,12 PentaE 14,19 TH01 6,9 TPOX 8 vWA 18 D6S1043 11,14 D12S391 20 D2S441 10,14 -
STR鑒定圖
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參考文獻(xiàn)
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MACF1 promotes osteoblast differentiation by sequestering repressors in cytoplasm(2021/03/04)
作者：Lifang Hu, Chong Yin, Dong Chen
期刊：cell death and differentiation
DOI：10.1038/s41418-021-00744-9
影響因子 ：12.400
引用產(chǎn)品：CL-0202
-
Bone-targeting exosome nanoparticles activate Keap1 / Nrf2 / GPX4 signaling pathway to induce ferroptosis in osteosarcoma cells(2023/09/30)
作者：Wenkai Chen, Zongguang Li, Naichun Yu
期刊：JOURNAL OF NANOBIOTECHNOLOGY
DOI：10.1186/s12951-023-02129-1
影響因子 ：10.200
-
Single-Atom Cu Nanozyme-Loaded Bone Scaffolds for Ferroptosis-Synergized Mild Photothermal Therapy in Osteosarcoma Treatment(2024/02/29)
作者：Zuyun Yan, Xin Wu, Wei Tan
期刊：Advanced Healthcare Materials
影響因子 ：10.000
引用產(chǎn)品：CL-0202
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Developing a Versatile Multiscale Therapeutic Platform for Osteosarcoma Synergistic Photothermo-Chemotherapy with Effective Osteogenicity and Antibacterial Capability(2022/09/20)
作者：Yunlong Ma, Lan Jiang, Jie Hu
期刊：ACS Applied Materials & Interfaces
影響因子 ：9.500
引用產(chǎn)品：CL-0202
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Single-cell and spatial transcriptomics reveal metastasis mechanism and microenvironment remodeling of lymph node in osteosarcoma(2024/05/17)
作者：Yun Liu, Mingwei He, Haijun Tang
期刊：BMC Medicine
DOI：10.1186/s12916-024-03319-w
影響因子 ：9.300
引用產(chǎn)品：CL-0202
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lncRNA MELTF-AS1 facilitates osteosarcoma metastasis by modulating MMP14 expression(2021/08/26)
作者：Lei Ding, Taiyuan Liu, Yuan Qu
期刊：Molecular Therapy-Nucleic Acids
DOI：10.1016/j.omtn.2021.08.022
影響因子 ：8.800
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Comprehensive analysis of a glycolysis and cholesterol synthesis-related genes signature for predicting prognosis and immune landscape in osteosarcoma(2022/12/23)
作者：Fangxing Xu, Jinglong Yan, Zhibin Peng
期刊：Frontiers in Immunology
DOI：10.3389/fimmu.2022.1096009
影響因子 ：8.786
引用產(chǎn)品：CL-0202
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Osteoporotic bone loss from excess iron accumulation is driven by NOX4-triggered ferroptosis in osteoblasts(2023/02/03)
作者：Hui Zhang, Aifei Wang, Guangfei Li
期刊：FREE RADICAL BIOLOGY AND MEDICINE
DOI：10.1016/j.freeradbiomed.2023.01.026
影響因子 ：7.400
引用產(chǎn)品：CL-0202
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Exploring the immune microenvironment of osteosarcoma through T cell exhaustion-associated gene expression: a study on prognosis prediction(2023/12/15)
作者：Junchao Zhu, Jinghong Yuan, Shahrzad Arya
期刊：Frontiers in Immunology
DOI：10.3389/fimmu.2023.1265098
影響因子 ：7.300
引用產(chǎn)品：CL-0202
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Multi-omics analysis reveals cuproptosis and mitochondria-based signature for assessing prognosis and immune landscape in osteosarcoma(2024/01/05)
作者：Chenguang Jia, Mei Liu, Liming Yao
期刊：Frontiers in Immunology
DOI：10.3389/fimmu.2023.1280945
影響因子 ：7.300
引用產(chǎn)品：CL-0202
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CKB affects human osteosarcoma progression by regulating the p53 pathway(2022/10/15)
作者：Fengxin Zhou, Xinli Dou, Chenguang Li
期刊：American Journal of Cancer Research
DOI：PMID:36381321
影響因子 ：5.942
引用產(chǎn)品：CL-0202
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Sirt1 modulates H3 phosphorylation and facilitates osteosarcoma cell autophagy(2019/08/07)
作者：Hongliang Ying, Boda Ying, Jinrui Zhang
期刊：Artificial Cells Nanomedicine and Biotechnology
DOI：10.1080/21691401.2019.1648280
影響因子 ：5.800
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Quantitative phosphoproteomic analysis reveals chemoresistance-related proteins and signaling pathways induced by rhIL-6 in human osteosarcoma cells(2021/10/30)
作者：Rui Zhang, Huan Wang, Erliang Li
期刊：Cancer Cell International
DOI：10.1186/s12935-021-02286-z
影響因子 ：5.800
引用產(chǎn)品：CL-0202
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ADAM10 promotes cell growth, migration, and invasion in osteosarcoma via regulating E-cadherin/β-catenin signaling pathway and is regulated by miR-122-5p(2020/03/30)
作者：Quan Yuan, Honghao Yu, Jianhua Chen
期刊：Cancer Cell International
DOI：10.1186/s12935-020-01174-2
影響因子 ：5.800
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A1BG-AS1 promotes the biological functions of osteosarcoma cells via regulating the microRNA-148a-3p/USP22 axis and stabilizing the expression of SIRT1 through deubiquitinase function(2023/10/03)
作者：Xiuxin Han, Mengfan Yin, Chen Gong
期刊：EXPERT OPINION ON THERAPEUTIC TARGETS
DOI：10.1080/14728222.2023.2263908
影響因子 ：5.800
引用產(chǎn)品：CL-0202
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Soy isoflavones induces mitophagy to inhibit the progression of osteosarcoma by blocking the AKT/mTOR signaling pathway(2024/01/08)
作者：Ziang Zheng, Xinghan Zhao, Bo Yuan
期刊：MOLECULAR MEDICINE
DOI：10.1186/s10020-024-00778-y
影響因子 ：5.700
引用產(chǎn)品：CL-0202
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Circular RNA hsa_circ_001350 contributes to osteosarcoma progression by regulating microRNA-578/CCR4-NOT transcription complex and subunit 7/Wnt signaling(2023/06/15)
作者：Rujin Xu, Xingyuan Ci, Fang He
期刊：American Journal of Cancer Research
DOI：PMID:37424831
影響因子 ：5.300
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Antitumor Effect of miR-1294/Pyruvate Kinase M2 Signaling Cascade in Osteosarcoma Cells(2020/2/21)
作者：Quan Yuan, Honghao Yu, Jianhua Chen
期刊：OncoTargets and Therapy
影響因子 ：4.000
引用產(chǎn)品：CL-0202
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Down-regulation of PRR11 affects the proliferation, migration and invasion of osteosarcoma by inhibiting the Wnt/β-catenin pathway(2021/09/13)
作者：Ke Li,?Hongtao Yu,?Chunbing Zhao
期刊：Journal of Cancer
影響因子 ：3.900
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Schisandrin B Inhibits Cell Viability and Migration, and Induces Cell Apoptosis by circ_0009112/miR-708-5p Axis Through PI3K/AKT Pathway in Osteosarcoma(2021/12/22)
作者：Bing Wang, Xiaowei Wang, Xing Tong
期刊：Frontiers in Genetics
影響因子 ：3.700
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hsa_circ_0020378 regulating miR-339-3p/COL1A1 promotes osteosarcoma progression(2023/11/18)
作者：Liang Liu, Wenze Huang
期刊：CANCER BIOLOGY & THERAPY
DOI：10.1080/15384047.2023.2274120
影響因子 ：3.600
引用產(chǎn)品：CL-0202
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DEPDC1 and KIF4A synergistically inhibit the malignant biological behavior of osteosarcoma cells through Hippo signaling pathway(2023/02/27)
作者：Mingming Yang, Hang Zhang, Shichang Gao
期刊：Journal of Orthopaedic Surgery and Research
DOI：10.1186/s13018-023-03572-4
影響因子 ：2.600
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Exosomal miR-331-3p derived from chemoresistant osteosarcoma cells induces chemoresistance through autophagy(2023/11/22)
作者：Chenyang Meng, Yun Yang, Wei Feng
期刊：Journal of Orthopaedic Surgery and Research
DOI：10.1186/s13018-023-04338-8
影響因子 ：2.600
引用產(chǎn)品：CL-0202
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Ginsenoside Rg3 inhibits osteosarcoma progression by reducing circ_0003074 expression in a miR-516b-5p/KPNA4-dependent manner(2021/12/20)
作者：Tehasi Wang, Chengguang Zhang, Shuren Wang
期刊：Journal of Orthopaedic Surgery and Research
DOI：10.1186/s13018-021-02868-7
影響因子 ：2.600
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circATP2A2 promotes osteosarcoma progression by upregulating MYH9(2021/11/22)
作者：Xin Cao, Xianfeng Meng, Peng Fu
期刊：Open Medicine
影響因子 ：2.100
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產(chǎn)品資料
識(shí)別碼示意圖
![LS 174T [LS174T] (人結(jié)腸腺癌細(xì)胞) (STR鑒定正確)](/Public/upfile/pic/xbx/CL-0145-1.jpg)
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