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BT-549 (人乳腺管癌細(xì)胞) (STR鑒定正確)
貨號(hào)：CL-0041
規(guī)格：1×10?cells/T25培養(yǎng)瓶
價(jià)格： ￥1400
生長(zhǎng)培養(yǎng)基：RPMI-1640＋10% FBS＋10μg/mL Insulin＋1% P/S
產(chǎn)品概述
| 名稱 | BT-549 (人乳腺管癌細(xì)胞) (STR鑒定正確) |
| 別稱 | BT 549; BT.549; BT549 |
| 種屬 | 人 |
| 生長(zhǎng)特性 | 貼壁細(xì)胞 |
| 細(xì)胞形態(tài) | 上皮細(xì)胞樣 |
| 凍存條件 | 凍存液：55% 基礎(chǔ)培養(yǎng)基+40%FBS+5%DMSO 溫度：液氮 |
| 培養(yǎng)方案A（默認(rèn)） |
生長(zhǎng)培養(yǎng)基:
培養(yǎng)條件:
氣相：空氣，95%；CO2，5%, 溫度：37℃
|
| 推薦傳代比例 | 1:2-1:4 |
| 推薦換液頻率 | 2-3次/周 |
| 背景描述 | BT-549細(xì)胞的來源組織是一個(gè)乳頭狀侵入性導(dǎo)管瘤，7個(gè)局部淋巴結(jié)中3個(gè)已有轉(zhuǎn)移。由此組織建立的BT-549細(xì)胞是多態(tài)性的，包括上皮細(xì)胞樣組分和多核巨細(xì)胞。 |
| 年齡（性別） | 女性；72歲 |
| 組織來源 | 乳腺 |
| 細(xì)胞類型 | 腫瘤細(xì)胞 |
| 腫瘤類型 | 乳腺癌細(xì)胞 |
| 生物安全等級(jí) | BSL-1 |
| 倍增時(shí)間 | ~54-90 hours |
| 保藏機(jī)構(gòu) | ATCC; HTB-122 |
STR鑒定
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STR位點(diǎn)信息
Amelogenin X CSF1PO 10,12 D2S1338 17 D3S1358 18 D5S818 11 D7S820 9,10 D8S1179 14,16 D13S317 11 D16S539 8 D18S51 15 D19S433 15.2 D21S11 32.2 FGA 19 PentaD 13 PentaE 14 TH01 9.3 TPOX 8 vWA 15,18 D6S1043 11 D12S391 18,20 D2S441 11.3 -
STR鑒定圖
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參考文獻(xiàn)
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Elevated expression of the rhythm gene NFIL3 promotes the progression of TNBC by activating NF-κB signaling through suppression of NFKBIA transcription(2022/02/18)
作者：Weiwei Yang , Jing Li, Minghui Zhang
期刊：Journal Of Experimental & Clinical Cancer Research
DOI：10.1186/s13046-022-02260-1
影響因子 ：11.300
引用產(chǎn)品：CL-0016 CL-0041 CL-0097 CL-0101 CL-0114 CL-0184 CL-0215 CL-0525
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Development of a rare earth nanoprobe enables in vivo real-time detection of sentinel lymph node metastasis of breast cancer using NIR-IIb imaging(2023/08/04)
作者：Yuanyuan Zhu, Liang Song, Yongqu Zhang
期刊：CANCER RESEARCH
DOI：10.1158/0008-5472.CAN-22-3432
影響因子 ：11.200
引用產(chǎn)品：CL-0007 CL-0040 CL-0041 CL-0149 CL-0211 CL-0228 CL-0525
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PRMT5 reduces immunotherapy efficacy in triple-negative breast cancer by methylating KEAP1 and inhibiting ferroptosis(2023/06/01)
作者：Zhe Wang, Ruolei Li, Niuniu Ho
期刊：Journal for ImmunoTherapy of Cancer
影響因子 ：10.900
引用產(chǎn)品：CL-0007 CL-0041 CL-0093 CL-0149 CL-0211 CL-0228 CL-0525 CM-0007 CM-0041 CM-0093 CM-0149 CM-0211 CM-0228 CM-0525
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Phosphorylation of USP27X by GSK3β maintains the stability and oncogenic functions of CBX2(2023/11/29)
作者：Yushu Xing, Jirimu Ba-tu, Chongyang Dong
期刊：Cell Death & Disease
DOI：10.1038/s41419-023-06304-y
影響因子 ：9.000
引用產(chǎn)品：CL-0041
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Up-regulated circBACH2 contributes to cell proliferation, invasion, and migration of triple-negative breast cancer(2021/04/19)
作者：Xinxing Wang, Bingjian Xue, Yujie Zhang
期刊：Cell Death & Disease
DOI：10.1038/s41419-021-03684-x
影響因子 ：9.000
引用產(chǎn)品：CL-0040 CL-0041 CL-0149 CL-0150 CL-0152 CL-0290 CL-0525
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MCPIP1-mediated NFIC alternative splicing inhibits proliferation of triple-negative breast cancer via cyclin D1-Rb-E2F1 axis(2021/04/06)
作者：Fengxia Chen, Qingqing Wang, Xiaoyan Yu
期刊：Cell Death & Disease
DOI：10.1038/s41419-021-03661-4
影響因子 ：9.000
引用產(chǎn)品：CL-0005 CL-0041 CL-0114 CL-0150 CL-0290 CL-0525 PM150312B
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A novel nuclear localization region in SIPA1 determines protein nuclear distribution and epirubicin-sensitivity of breast cancer cells(2021/03/19)
作者：Ying Ma, Jun Weng, Ning Wang
期刊：International Journal Of Biological Macromolecules
DOI：10.1016/j.ijbiomac.2021.03.101
影響因子 ：8.200
引用產(chǎn)品：CL-0041
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A novel transcription factor SIPA1: identification and verification in triple-negative breast cancer(2023/07/27)
作者：Lijuan Guo, Wanjun Zhang, Xue Zhang
期刊：ONCOGENE
DOI：10.1038/s41388-023-02787-3
影響因子 ：8.000
引用產(chǎn)品：CL-0041
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Vertical pathway inhibition of receptor tyrosine kinases and BAD with synergistic efficacy in triple negative breast cancer(2024/01/10)
作者：Yanqin Tan, Hui Guo, Shuwei Zhang
期刊：npj Precision Oncology
DOI：10.1038/s41698-023-00489-3
影響因子 ：7.900
引用產(chǎn)品：CL-0041
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Calycosin inhibits triple-negative breast cancer cells progression through down-regulation of the novel estrogen receptor-α splice variant ER-α30-mediated PI3K/AKT signaling pathway(2023/06/14)
作者：Yuhong Li, Shuying Hu, Yueqi Chen
期刊：PHYTOMEDICINE
DOI：10.1016/j.phymed.2023.154924
影響因子 ：7.900
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DEPDC1B-mediated USP5 deubiquitination of β-catenin promotes breast cancer metastasis by activating the wnt/β-catenin pathway(2023/08/29)
作者：Qingqing Wang, Fengxia Chen, Ningning Yang
期刊：AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
DOI：10.1152/ajpcell.00249.2023
影響因子 ：5.500
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Jiawei Yanghe Decoction suppresses breast cancer by regulating immune responses via JAK2/STAT3 signaling pathway(2023/03/17)
作者：Yanting You, Xiaomei Chen, Xiaohu Chen
期刊：JOURNAL OF ETHNOPHARMACOLOGY
影響因子 ：5.400
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Circular RNA circ-ERBB2 Elevates the Warburg Effect and Facilitates Triple-Negative Breast Cancer Growth by the MicroRNA 136-5p/Pyruvate Dehydrogenase Kinase 4 Axis | Molecular and Cellular Biology(2021/09/24)
作者：Yihong Huang, Shuo Zheng, Ying Lin, Liming Kea
期刊：Molecular And Cellular Biology
影響因子 ：5.300
引用產(chǎn)品：164210 CL-0041 CL-0150 CL-0152 CL-0290 CL-0525 PB180120 PM150110 PM151010
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Circular RNA circ-ERBB2 Elevates the Warburg Effect and Facilitates Triple-Negative Breast Cancer Growth by the MicroRNA 136-5p/Pyruvate Dehydrogenase Kinase 4 Axis(2023/03/03)
作者：Yihong Huang, Shuo Zheng, Ying Lin
期刊：MOLECULAR AND CELLULAR BIOLOGY
影響因子 ：5.300
引用產(chǎn)品：CL-0041
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The Curcumin Analog EF24 Inhibits Proliferation and Invasion of Triple-Negative Breast Cancer Cells by Targeting the Long Noncoding RNA HCG11/Sp1 Axis(2023/02/27)
作者：Yin Duan, Huiling Chen, Min Ling
期刊：MOLECULAR AND CELLULAR BIOLOGY
影響因子 ：5.300
引用產(chǎn)品：CL-0041
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The curcumin analog EF24 inhibits proliferation and invasion of triple-negative breast cancer cells by targeting the lncRNA HCG11/Sp1 axis | Molecular and Cellular Biology(2021/11/15)
作者：Yin Duan, Huiling Chen, Min Ling
期刊：Molecular And Cellular Biology
影響因子 ：5.300
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Constructing a novel prognostic model for triple-negative breast cancer based on genes associated with vasculogenic mimicry(2024/05/08)
作者：Yu Ren, Luyi Feng, Zhihua Tan
期刊：Aging-US
影響因子 ：5.200
引用產(chǎn)品：CL-0041
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Knockdown of circular RNA septin 9 inhibits the malignant progression of breast cancer by reducing the expression of solute carrier family 1 member 5 in a microRNA-149-5p-dependent manner(2021/10/27)
作者：Jianjun Wang, Kunxian Yang, Junyu Cao
期刊：Bioengineered
DOI：10.1080/21655979.2021.2000731
影響因子 ：4.900
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Extracellular vesicles released by hypoxia-induced tumor-associated fibroblasts impart chemoresistance to breast cancer cells via long noncoding RNA H19 delivery(2024/01/10)
作者：Shuang Tao, Jian Wang, Fang Li
期刊：FASEB JOURNAL
影響因子 ：4.800
引用產(chǎn)品：CL-0041
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Baicalein promotes KDM4E to induce BICD1 and inhibit triple-negative breast cancer progression by blocking PAR1 signaling(2024/04/12)
作者：Yun Dong, Gaojian He, Kun Chen
期刊：MOLECULAR CARCINOGENESIS
DOI：10.1002/mc.23724
影響因子 ：4.600
引用產(chǎn)品：CL-0041
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Immunogenic cell death-related classification reveals prognosis and effectiveness of immunotherapy in breast cancer(2024/01/23)
作者：Lei Zhu, Yanmei Wu, Haichun Zhao
期刊：Scientific Reports
DOI：10.1038/s41598-024-52353-4
影響因子 ：4.600
引用產(chǎn)品：CL-0041
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Neutrophil extracellular trap-associated risk index for predicting outcomes and response to Wnt signaling inhibitors in triple-negative breast cancer(2024/02/20)
作者：Zhidong Huang, Jinhui Wang, Bo Sun
期刊：Scientific Reports
DOI：10.1038/s41598-024-54888-y
影響因子 ：4.600
引用產(chǎn)品：CL-0041
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Low-dose aspirin can inhibit exosomal release induced by radiotherapy in breast cancer and attenuate its inhibitory effect on NK cell proliferation(2023/07/01)
作者：Li Wang, Zaoxiu Hu, Ceshi Chen
期刊：Cancer Medicine
影響因子 ：4.000
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The inhibition of centromere protein K causes anticancer effects in breast carcinoma via effects on the FAK/PI3K/AKT/mTOR pathway(2022/09/09)
作者：Jiao Yu, Kai Wang, Sanhu Yang
期刊：TOXICOLOGY AND APPLIED PHARMACOLOGY
DOI：10.1016/j.taap.2022.116232
影響因子 ：3.800
引用產(chǎn)品：CL-0041 CL-0114 CL-0149 CL-0228 CL-0324 CL-0525 PM150110 PM150312 PM150411
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LncRNA AFAP1-AS1 Knockdown Represses Cell Proliferation, Migration, and Induced Apoptosis in Breast Cancer by Downregulating SEPT2 Via Sponging miR-497-5p(2022/10/12)
作者：Bo Cai, Xichao Wang, Qingao Bu
期刊：CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS
影響因子 ：3.632
引用產(chǎn)品：CL-0041
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circKLHL24 Blocks Breast Cancer Development by Regulating the miR-1204/ALX4 Network(2022/10/12)
作者：Guangming Yi, Dan Wang, Jianjun Han
期刊：CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS
影響因子 ：3.632
引用產(chǎn)品：CL-0041
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The combined effect and mechanism of antiangiogenic drugs and PD-L1 inhibitor on cell apoptosis in triple negative breast cancer(2023/01/31)
作者：Jing Li, Dianbao Zhang, Zhiwei Liu
期刊：Annals of Translational Medicine
影響因子 ：3.616
引用產(chǎn)品：CL-0041
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MiR‐96‐5p promotes breast cancer migration by activating MEK/ERK signaling(2020/02/02)
作者：Weiyan Qin, Shichun Feng, Yongqiang Sun
期刊：Journal Of Gene Medicine
DOI：10.1002/jgm.3188
影響因子 ：3.500
引用產(chǎn)品：CL-0041
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LncRNA AFAP1-AS1 Knockdown Represses Cell Proliferation, Migration, and Induced Apoptosis in Breast Cancer by Downregulating SEPT2 Via Sponging miR-497-5p(2020/09/21)
作者：Bo Cai, Xichao Wang, Qingao Bu
期刊：Cancer Biother And Radiopharm
影響因子 ：3.400
引用產(chǎn)品：CL-0041
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TTK inhibition activates STING signal and promotes anti-PD1 immunotherapy in breast cancer(2023/12/18)
作者：Xiang Hu, Guangmei Li, Sisi Li
期刊：BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
DOI：10.1016/j.bbrc.2023.149388
影響因子 ：3.100
引用產(chǎn)品：CL-0041
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Metadherin inhibits chemosensitivity of triple-negative breast cancer to paclitaxel via activation of AKT/GSK-3β signaling pathway(2023/12/13)
作者：Yan Chang, Huiqin Jia, Bin Xu
期刊：Chemical Biology & Drug Design
影響因子 ：3.000
引用產(chǎn)品：CL-0041
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Identification of TFR2 as a novel ferroptosis?related gene that serves an important role in prognosis and progression of triple?negative breast cancer(2023/12/05)
作者：Yan Yang, Jie Du, Yunfei Huang
期刊：Oncology Letters
影響因子 ：2.900
引用產(chǎn)品：CL-0041
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p53 downregulates PD-L1 expression via miR-34a to inhibit the growth of triple-negative breast cancer cells: a potential clinical immunotherapeutic target(2022/11/09)
作者：Deng, Siyu, Wang, Mengna, Wang, Chenglong, Zeng, Yan, Qin, Xue, Tan, Yiwen, Liang, Bing, Cao, Youde
期刊：MOLECULAR BIOLOGY REPORTS
DOI：10.1007/s11033-022-08047-z
影響因子 ：2.800
引用產(chǎn)品：CL-0041
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Calcium-sensing Receptor, a Potential Biomarker Revealed by Large-scale Public Databases and Experimental Verification in Metastatic Breast Cancer(2024/05/23)
作者：Wanlin Xie, Huimin Xu, Yangyang Cheng
期刊：TECHNOLOGY IN CANCER RESEARCH & TREATMENT
影響因子 ：2.800
引用產(chǎn)品：CL-0041
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DNAJB4 suppresses breast cancer progression and promotes tumor immunity by regulating the Hippo signaling pathway(2023/08/07)
作者：Yanru Chen, Jingjia Li, Lulan Pu
期刊：Discover Oncology
DOI：10.1007/s12672-023-00762-8
影響因子 ：2.200
引用產(chǎn)品：CL-0041
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Hsa_circ_0069094 positively regulates the expression of oncogenic ZNF217 by competitively targeting miR-758–3p to promote the development of breast cancer(2022/11/08)
作者：Huaqing Ou, Jialing Li, Qinhua Lv, Decai Feng
期刊：Reproductive Biology
DOI：10.1016/j.repbio.2022.100708
影響因子 ：2.100
引用產(chǎn)品：CL-0041 CL-0150 CL-0525 PM150110 PM150210 PM151010
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FEZF2 inhibits the growth of triple-negative breast cancer cells through EZH2/PD-L1 and enhances anti-tumor immunity in vivo(2023/06/19)
作者：Wenyu Li, Hu Liu, Wenjuan Li
期刊：Molecular & Cellular Toxicology
DOI：10.1007/s13273-023-00368-9
影響因子 ：1.700
引用產(chǎn)品：164215 CL-0041 CL-0525 PB180120 PM150110 PM150210 PM150312
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SIPA1 enhances SMAD2/3 expression to maintain stem cell features in breast cancer cells(2020/11/24)
作者：Ning Wang, Jun Weng, Jing Xia
期刊：Stem Cell Research
影響因子 ：1.200
引用產(chǎn)品：CL-0041
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